2-BROMO-4-FLUORO-6-NITROANILINE

Product Name: 2-BROMO-4-FLUORO-6-NITROANILINE
CAS No.: 10472-88-5
Chemical Name: 2-BROMO-4-FLUORO-6-NITROANILINE
Synonyms: SKL366;2-BROMO-4-FLUORO-6-NITROANILINE;2-Bromo-4-fluoro-6-nitroaniline98%;2-Bromo-4-fluoro-6-nitroaniline 98%;2-bromo-4-fluoro-6-nitrobenzenamine;2-Bromo-4-fluoro-6-nitroaniline, 97%;2-Amino-3-bromo-5-fluoronitrobenzene;BenzenaMine, 2-broMo-4-fluoro-6-nitro-;2-Bromo-4-fluoro-6-nitroaniline,tech.90%;Benzenebutanoicacid,7-fluoro-α,γ-dioxo-,ethylester
CBNumber: CB7159910
Molecular Formula: C6H4BrFN2O2
Formula Weight: 235.01
MOL File: 10472-88-5.mol

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2-BROMO-4-FLUORO-6-NITROANILINE Property

Melting point:: 70-72°C
Boiling point:: 313.9±37.0 °C(Predicted)
Density: 1.896±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
form: Powder
pka: -2.32±0.25(Predicted)
color: Orange
InChI: InChI=1S/C6H4BrFN2O2/c7-4-1-3(8)2-5(6(4)9)10(11)12/h1-2H,9H2
InChIKey: HCYDUPDSEDHSQB-UHFFFAOYSA-N
SMILES: C1(N)=C([N+]([O-])=O)C=C(F)C=C1Br

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Safety

Hazard Codes: T
HazardClass: 6.1
HS Code: 2921420090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TCI Chemical

Product number: B4872
Product name: 2-Bromo-4-fluoro-6-nitroaniline
Purity: >98.0%(GC)
Packaging: 1g
Price: $118
Updated: 2025/07/31

TRC

Product number: B679175
Product name: 2-Bromo-4-fluoro-6-nitroaniline
Packaging: 250mg
Price: $45
Updated: 2021/12/16

ChemScene

Product number: CS-W001097
Product name: 2-Bromo-4-fluoro-6-nitroaniline
Packaging: 5g
Price: $40
Updated: 2021/12/16

AK Scientific

Product number: X8725
Product name: 2-Bromo-4-fluoro-6-nitroaniline
Packaging: 1g
Price: $70
Updated: 2021/12/16

Matrix Scientific

Product number: 081208
Product name: 2-Bromo-4-fluoro-6-nitroaniline
Purity: 97%
Packaging: 1g
Price: $76
Updated: 2021/12/16

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2-BROMO-4-FLUORO-6-NITROANILINE Chemical Properties,Usage,Production

Chemical Properties

off-white powder

Uses

2-Bromo-4-fluoro-6-nitroaniline is used as pharmaceutical intermediate.

Synthesis

364-78-3

10472-88-5

The general procedure for the synthesis of 2-bromo-4-fluoro-6-nitroaniline from 4-fluoro-2-nitroaniline is as follows: 1. 4-fluoro-2-nitroaniline (10.0 g, 42.55 mmol) was dissolved in dichloromethane (DCM) to prepare a mixture. 2. a mixture of bromine (Br2, 9.9 ml, 130 mmol) in dichloromethane (110 mL, pre-cooled to 0 °C) and acetic acid (HOAc, 75 mL) was slowly added dropwise at 0 °C, with the rate of dropwise acceleration being controlled to keep the internal reaction temperature below 10 °C. 3. After titration, the reaction mixture was stirred at room temperature overnight. 4. The reaction mixture was poured into water (500 mL) to separate the organic phase. 5. The pH of the aqueous phase was adjusted to about 7 with ammonium hydroxide (NH4OH) and then the aqueous phase was extracted with dichloromethane (DCM, 100 mL x 3). 6. The organic extracts were combined, dried with magnesium sulfate (MgSO4), filtered and concentrated in vacuum to give 2-bromo-4-fluoro-6-nitroaniline as a yellow solid (14 g, 93% yield). Mass spectrum (ESI): m/z = 233 [M-1].

References

[1] Patent: US5606063, 1997, A
[2] Patent: WO2013/26914, 2013, A1. Location in patent: Page/Page column 118
[3] Patent: CN108218887, 2018, A. Location in patent: Paragraph 0094; 0097; 0098; 0099
[4] Journal of Antibiotics, 1994, vol. 47, # 12, p. 1456 - 1465
[5] Patent: US2006/229289, 2006, A1. Location in patent: Page/Page column 25

2-BROMO-4-FLUORO-6-NITROANILINE Preparation Products And Raw materials

Raw materials

Preparation Products

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2-BROMO-4-FLUORO-6-NITROANILINE Suppliers

Americas 1 CHINA 101 Europe 1 France 1 Germany 4 India 8 Italy 1 Japan 1 The Netherlands 1 United Kingdom 10 United States 27 Global 156

Shanghai Harvest Chemical Industrial Co., Ltd.

Tel: 021-31038972,31038973 17321035817
Fax: +86-21-51385350
Email: sales@harvest-chem.com
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Shanghai Sphchem Co., Ltd.

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J & K SCIENTIFIC LTD.

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Shijiazhuang Sdyano Fine Chemical Co., Ltd.

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Wuhan Chemwish Technology Co., Ltd

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Capot Chemical Co., Ltd

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JinYan Chemicals(ShangHai) Co.,Ltd.

Tel: 13817811078
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Shanghai Sinch Parmaceuticals Tech. Co. Ltd.

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View Lastest Price from 2-BROMO-4-FLUORO-6-NITROANILINE manufacturers

Henan Fengda Chemical Co., Ltd

Product: 2-BROMO-4-FLUORO-6-NITROANILINE 10472-88-5
Price: US $100.00-1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2023-12-26

Qiuxian Baitai New Material Co., LTD

Product: 2-Bromo-4-fluoro-6-n 10472-88-5
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 500ton/Month
Release date: 2021-07-29

Shaanxi Dideu Medichem Co. Ltd

Product: 2-Bromo-4-fluoro-6-nitroaniline 10472-88-5
Price: US $0.00-0.00/Kg
Min. Order: 1KG
Purity: 99.0%
Supply Ability: 100 tons
Release date: 2020-01-10

10472-88-5, 2-BROMO-4-FLUORO-6-NITROANILINERelated Search:

2-Bromo-6-fluoro-4-nitroaniline 4-BROMO-2-FLUORO-6-NITROANILINE 4-BROMO-2-FLUORO-5-NITROANILINE 4-Bromo-5-fluoro-2-nitroaniline 4-BROMO-3-FLUORO-2-NITROANILINE 2-BROMO-6-NITROANILINE 2-BROMO-4-FLUORO-6-NITROANILINE 3-Bromo-1,2-diaminobenzene 1-Bromo-3-fluoro-5-nitrobenzene

2-Bromo-4-fluoro-6-nitroaniline 98%

2-Bromo-4-fluoro-6-nitroaniline98%

2-BROMO-4-FLUORO-6-NITROANILINE

BenzenaMine, 2-broMo-4-fluoro-6-nitro-

2-bromo-4-fluoro-6-nitrobenzenamine

2-Amino-3-bromo-5-fluoronitrobenzene

2-Bromo-4-fluoro-6-nitroaniline,tech.90%

2-BROMO-4-FLUORO-6-NITROANILINE ISO 9001：2015 REACH

SKL366

Benzenebutanoicacid,7-fluoro-α,γ-dioxo-,ethylester

2-Bromo-4-fluoro-6-nitroaniline, 97%

10472-88-5

C6H4BrFN2O2

C6H4BrN2O2

Amines

Phenyls & Phenyl-Het