2-[4-(4-Aminophenyl)piperazin-1-yl]ethan-1-ol
- Product Name
- 2-[4-(4-Aminophenyl)piperazin-1-yl]ethan-1-ol
- CAS No.
- 5521-39-1
- Chemical Name
- 2-[4-(4-Aminophenyl)piperazin-1-yl]ethan-1-ol
- Synonyms
- AKOS BB1150;VITAS-BB TBB005536;OTAVA-BB 7020694390;2-(4-(4-Aminophenyl);1-Piperazineethanol, 4-(4-aminophenyl)-;4-[4-(2-Hydroxyethyl)piperazin-1-yl]aniline;2-[4-(4-Aminophenyl)piperazin-1-yl]ethan-1-ol;4-[4-(2-Hydroxyethyl)piperazin-1-yl]aniline 97%
- CBNumber
- CB11262901
- Molecular Formula
- C12H19N3O
- Formula Weight
- 221.3
- MOL File
- 5521-39-1.mol
2-[4-(4-Aminophenyl)piperazin-1-yl]ethan-1-ol Property
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- Appearance
- Brown to black Solid
Safety
- HazardClass
- IRRITANT
- HS Code
- 2933599590
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- A639580
- Product name
- 2-(4-(4-Aminophenyl)piperazin-1-yl)ethanol
- Packaging
- 50mg
- Price
- $110
- Updated
- 2021/12/16
- Product number
- 051264
- Product name
- 2-[4-(4-Aminophenyl)-1-piperazinyl]-1-ethanol
- Packaging
- 500mg
- Price
- $250
- Updated
- 2021/12/16
- Product number
- 020754
- Product name
- 2-[4-(4-Amino-phenyl)-piperazin-1-yl]-ethanol dihydrochloride
- Packaging
- 1g
- Price
- $308
- Updated
- 2021/12/16
- Product number
- 051264
- Product name
- 2-[4-(4-Aminophenyl)-1-piperazinyl]-1-ethanol
- Packaging
- 1g
- Price
- $400
- Updated
- 2021/12/16
- Product number
- CHM0002732
- Product name
- 2-[4-(4-AMINO-PHENYL)-PIPERAZIN-1-YL]ETHANOL
- Purity
- 95.00%
- Packaging
- 500MG
- Price
- $777.32
- Updated
- 2021/12/16
2-[4-(4-Aminophenyl)piperazin-1-yl]ethan-1-ol Chemical Properties,Usage,Production
Synthesis
5521-38-0
5521-39-1
2-[4-(4-nitrophenyl)piperazin-1-yl]ethanol (3.6 g, 14.3 mmol) was used as a starting material and dissolved in methanol (40 mL). To this solution was added palladium/carbon catalyst (700 mg) and the reaction mixture was stirred at 0 °C overnight. After completion of the reaction, the catalyst was removed by filtration and the filtrate was concentrated to afford the target product 2-[4-(4-aminophenyl)piperazin-1-yl]ethanol (2.8 g, 88% yield) as a yellow solid.
References
[1] Patent: WO2015/27222, 2015, A2. Location in patent: Paragraph 0323
[2] Patent: WO2012/59932, 2012, A1. Location in patent: Page/Page column 113
[3] Journal of Medicinal Chemistry, 2005, vol. 48, # 7, p. 2371 - 2387
[4] Patent: US2004/87575, 2004, A1
[5] Patent: US2003/13708, 2003, A1
2-[4-(4-Aminophenyl)piperazin-1-yl]ethan-1-ol Preparation Products And Raw materials
Raw materials
Preparation Products
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