4-N-PROPOXYBENZALDEHYDE
- Product Name
- 4-N-PROPOXYBENZALDEHYDE
- CAS No.
- 5736-85-6
- Chemical Name
- 4-N-PROPOXYBENZALDEHYDE
- Synonyms
- NSC 32509;NSC 406729;WLN: VHR DO3;ASISCHEM V31873;AKOS BBS-00003252;TIMTEC-BB SBB008225;Propoxybenzaldehyde;4-propoxy-benzaldehyd;OTAVA-BB BB7020401736;P-PROPOXYBENZALDEHYDE
- CBNumber
- CB1126589
- Molecular Formula
- C10H12O2
- Formula Weight
- 164.2
- MOL File
- 5736-85-6.mol
4-N-PROPOXYBENZALDEHYDE Property
- Melting point:
- 268 °C
- Boiling point:
- 129-130 °C/10 mmHg (lit.)
- Density
- 1.039 g/mL at 25 °C (lit.)
- refractive index
- n20/D 1.546(lit.)
- Flash point:
- >230 °F
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- form
- clear liquid
- color
- Colorless to Light orange to Yellow
- Specific Gravity
- 1.06
- Sensitive
- Air Sensitive
- BRN
- 743408
- InChI
- InChI=1S/C10H12O2/c1-2-7-12-10-5-3-9(8-11)4-6-10/h3-6,8H,2,7H2,1H3
- InChIKey
- FGXZWMCBNMMYPL-UHFFFAOYSA-N
- SMILES
- C(=O)C1=CC=C(OCCC)C=C1
- CAS DataBase Reference
- 5736-85-6(CAS DataBase Reference)
- EPA Substance Registry System
- Benzaldehyde, 4-propoxy- (5736-85-6)
Safety
- Hazard Codes
- Xn,Xi
- Risk Statements
- 20/21/22-36/37/38
- Safety Statements
- 26-27-36/37/39
- WGK Germany
- 3
- RTECS
- CU7700000
- TSCA
- T
- HazardClass
- IRRITANT
- HS Code
- 29124990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 333638
- Product name
- 4-Propoxybenzaldehyde
- Purity
- 97%
- Packaging
- 5g
- Price
- $42.1
- Updated
- 2023/01/07
- Product number
- P0182
- Product name
- 4-Propoxybenzaldehyde
- Purity
- >97.0%(GC)
- Packaging
- 25mL
- Price
- $56
- Updated
- 2025/07/31
- Product number
- B524813
- Product name
- 4-propoxybenzaldehyde
- Packaging
- 2.5mg
- Price
- $75
- Updated
- 2021/12/16
- Product number
- 038303
- Product name
- 4-Propoxybenzaldehyde
- Packaging
- 500mg
- Price
- $76
- Updated
- 2021/12/16
- Product number
- J54113
- Product name
- 4-Propoxybenzaldehyde
- Packaging
- 25g
- Price
- $49
- Updated
- 2021/12/16
4-N-PROPOXYBENZALDEHYDE Chemical Properties,Usage,Production
Chemical Properties
White liquid
Uses
4-Propoxybenzaldehyde was used in the preparation of (2S,4S,5R)-(±)-2-(4-propoxyphenyl)-3,4-dimethyl-5-phenyl-1,3-oxazolidine via condensation with 1-ephedrine.
General Description
Kinetic constants for the inhibition of the diphenolase activity of mushroom tyrosinase by 4-propoxybenzaldehyde was evaluated.
Synthesis
123-08-0
106-94-5
5736-85-6
Step C: Synthesis of 3-chloro-4-propoxybenzaldehyde: A mixture of 4-hydroxybenzaldehyde (0.5 g, 4.1 mmol), 1-bromopropane (0.3 ml), and K2CO3 (0.69 g, 5 mmol) in anhydrous DMF (5 ml) was stirred and refluxed for 1 hour. After completion of the reaction, it was diluted to 100 ml with EtOAc and washed with H2O. The organic layer was separated, dried with MgSO4 and filtered. The filtrate was evaporated to dryness to give 4-propoxybenzaldehyde (0.55 g, 82.3%) as a yellow oil.1H-NMR (CDCl3) δ: 1.0 (t, 3H, J=7.41Hz); 1.7-2.0 (m, 2H); 3.95 (t, 2H, J=6.57Hz); 6.95 (d, 2H, J=8.73Hz); 8.00 (d, 2H, J=8.76Hz). To a stirred solution of 4-propoxybenzaldehyde (0.5 g, 3.07 mmol) in anhydrous DMF (3 ml) was added N-chlorosuccinimide (NCS, 0.5 g, 3.73 mmol) and the mixture was stirred at room temperature overnight. After completion of the reaction, it was diluted to 100 ml with EtOAc and washed with NaHCO3 solution (100 ml). The organic layer was separated, dried with MgSO4 and filtered. The filtrate was evaporated to dryness to give the crude product 3-chloro-4-propoxybenzaldehyde (0.59 g; 97%) as a light yellow oil.1H-NMR (CDCl3) δ: 9.81 (s, 1H); 7.87 (d, 1H, J=2.01 Hz); 7.71 (dd, 1H, J=2.02-8.47Hz); 6.98 (d, 1H, J= 8.47 Hz); 1.82-1.91 (m, 2H); 4.1 (t, 2H, J=6.3 Hz); 1.1 (t, 3H, J=7.4 Hz).
References
[1] Chemical Communications, 2013, vol. 49, # 54, p. 6042 - 6044
[2] Macromolecules, 2012, vol. 45, # 17, p. 6840 - 6849,10
[3] Patent: WO2010/42998, 2010, A1. Location in patent: Page/Page column 117; 118
[4] Patent: WO2014/63199, 2014, A1. Location in patent: Page/Page column 69
[5] Molecular Crystals and Liquid Crystals (1969-1991), 1988, vol. 154, p. 267 - 276
4-N-PROPOXYBENZALDEHYDE Preparation Products And Raw materials
Raw materials
Preparation Products
4-N-PROPOXYBENZALDEHYDE Suppliers
- Tel
- --
- Fax
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- y.barysheva@ukrorgsynth.com
- Country
- Ukraine
- ProdList
- 6230
- Advantage
- 38
- Tel
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- north.america@otavachemicals.com
- Country
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View Lastest Price from 4-N-PROPOXYBENZALDEHYDE manufacturers
- Product
- 4-Propoxybenzaldehyde 5736-85-6
- Price
- US $0.00-0.00/g
- Min. Order
- 10mg
- Purity
- 99%HPLC
- Supply Ability
- 2000tons
- Release date
- 2020-01-15
- Product
- 4-N-PROPOXYBENZALDEHYDE 5736-85-6
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-08-11
- Product
- 4-N-PROPOXYBENZALDEHYDE 5736-85-6
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 200kg
- Release date
- 2020-01-09