ETHYL 5-CHLOROTHIOPHENE-2-CARBOXYLATE
- Product Name
- ETHYL 5-CHLOROTHIOPHENE-2-CARBOXYLATE
- CAS No.
- 5751-82-6
- Chemical Name
- ETHYL 5-CHLOROTHIOPHENE-2-CARBOXYLATE
- Synonyms
- RARECHEM AL BI 0303;Rivaroxaban impurity P2-O;Ethyl 5-chlorothiophene-2-carboxlate;Ethyl 5-chloro-2-thiophenecarboxylate;2- chlorinethiophene -5-ethyl forMate;ETHYL 5-CHLOROTHIOPHENE-2-CARBOXYLATE;Ethyl5-Chlorothiophene-2-carboxylate>Ethyl 5-chlorothiophene-2-carboxylate, 98+%;5-chloro-2-thiophenecarboxylic acid ethyl ester;5-Chlorothiophene-2-carboxylic acid ethyl ester
- CBNumber
- CB1127142
- Molecular Formula
- C7H7ClO2S
- Formula Weight
- 190.65
- MOL File
- 5751-82-6.mol
ETHYL 5-CHLOROTHIOPHENE-2-CARBOXYLATE Property
- Boiling point:
- 70-71°C 1mm
- Density
- 1.312±0.06 g/cm3(Predicted)
- refractive index
- 1.5380
- Flash point:
- 70-71°C/1mm
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- form
- clear liquid
- color
- Colorless to Light yellow
- BRN
- 128707
- CAS DataBase Reference
- 5751-82-6
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- E1112
- Product name
- Ethyl 5-Chlorothiophene-2-carboxylate
- Purity
- >98.0%(GC)
- Packaging
- 1g
- Price
- $26
- Updated
- 2025/07/31
- Product number
- E1112
- Product name
- Ethyl 5-Chlorothiophene-2-carboxylate
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $85
- Updated
- 2025/07/31
- Product number
- E903593
- Product name
- Ethyl 5-Chlorothiophene-2-carboxylate
- Packaging
- 250mg
- Price
- $55
- Updated
- 2021/12/16
- Product number
- E903593
- Product name
- Ethyl 5-Chlorothiophene-2-carboxylate
- Packaging
- 1g
- Price
- $75
- Updated
- 2021/12/16
- Product number
- 45001
- Product name
- Ethyl5-Chlorothiophene-2-carboxylate,≥98%(GC)
- Purity
- ≥98%(GC)
- Packaging
- 1G
- Price
- $36.7
- Updated
- 2021/12/16
ETHYL 5-CHLOROTHIOPHENE-2-CARBOXYLATE Chemical Properties,Usage,Production
Chemical Properties
Colorless to light yellow liquid
Synthesis
24065-33-6
64-17-5
5751-82-6
Concentrated sulfuric acid (15 mL) was slowly added to a stirring solution of 5-chlorothiophene-2-carboxylic acid (15 g, 0.0925 mol) in ethanol (300 mL) at room temperature. The reaction mixture was stirred continuously under anhydrous conditions for 16 hours. Upon completion of the reaction, the reaction mixture was concentrated by distillation under reduced pressure. The concentrate was diluted with ethyl acetate (300 mL) and the organic layer was subsequently washed sequentially with water (3 x 100 mL), saturated sodium bicarbonate solution (3 x 100 mL) and saturated saline (100 mL). The organic layer was dried over anhydrous sodium sulfate and concentrated under reduced pressure to give ethyl 5-chlorothiophene-2-carboxylate (14 g, 80% yield) as a colorless liquid.
References
[1] Patent: WO2015/18534, 2015, A1. Location in patent: Page/Page column 39
[2] Journal of the American Chemical Society, 1954, vol. 76, p. 5131
[3] Journal of the American Chemical Society, 1954, vol. 76, p. 5131
[4] Chemistry - A European Journal, 2016, vol. 22, # 1, p. 211 - 221
ETHYL 5-CHLOROTHIOPHENE-2-CARBOXYLATE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from ETHYL 5-CHLOROTHIOPHENE-2-CARBOXYLATE manufacturers
- Product
- ETHYL 5-CHLOROTHIOPHENE-2-CARBOXYLATE 5751-82-6
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20 mt
- Release date
- 2024-12-10
- Product
- ETHYL 5-CHLOROTHIOPHENE-2-CARBOXYLATE 5751-82-6
- Price
- US $3.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2019-07-09