nimbolide

Product Name: nimbolide
CAS No.: 25990-37-8
Chemical Name: nimbolide
Synonyms: nimbolide;NSC 309909;Nimbolide (25 mg);Nimbolide, CyclinA and ERK1/2 inhibitor;(17R)-7α,15β:21,23-Diepoxy-6α-hydroxy-4,8-dimethyl-1-oxo-11-methoxycarbonyl-18,24-dinor-11,12-seco-5α-chola-2,13,20,22-tetrene-4α-carboxylic acid γ-lactone;methyl [(2aR,5aR,6S,6aR,8R,9aR,10aS,10bR,10cR)-8-furan-3-yl-2a,5a,6a,7-tetramethyl-2,5-dioxo-2a,5a,6,6a,8,9,9a,10a,10b,10c-decahydro-2H,5H-cyclopenta[d]naphtho[2,3-b:1,8-b''c'']difuran-6-yl]acetate;2H,5H-Cyclopenta[d']naphtho[1,8-bc:2,3-b']difuran-6-acetic acid, 8-(3-furanyl)-2a,5a,6,6a,8,9,9a,10a,10b,10c-decahydro-2a,5a,6a,7-tetramethyl-2,5-dioxo-, methyl ester, (2aR,5aR,6S,6aR,8R,9aR,10aS,10bR,10cR)-
CBNumber: CB11328652
Molecular Formula: C27H30O7
Formula Weight: 466.52
MOL File: 25990-37-8.mol

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nimbolide Property

Melting point:: >223°C (dec.)
Boiling point:: 608.6±55.0 °C(Predicted)
Density: 1.32±0.1 g/cm3(Predicted)
storage temp.: Hygroscopic, -20°C Freezer, Under Inert Atmosphere
solubility: Chloroform, Ethyl Acetate
form: powder
color: Light Beige to Yellow

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Safety

RTECS: GY2370000
Toxicity: hamster,LD50,intraperitoneal,> 500mg/kg (500mg/kg),Toxicology Letters. Vol. 30, Pg. 159, 1986.

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Warning
Hazard statements: H302Harmful if swallowed

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SMB00586
Product name: Nimbolide
Purity: from Azadirachta indica, ≥98%
Packaging: 5mg
Price: $493
Updated: 2024/03/01

Cayman Chemical

Product number: 19230
Product name: Nimbolide
Purity: ≥97%
Packaging: 5mg
Price: $251
Updated: 2024/03/01

Cayman Chemical

Product number: 19230
Product name: Nimbolide
Purity: ≥97%
Packaging: 25mg
Price: $1058
Updated: 2024/03/01

Tocris

Product number: 7289
Product name: Nimbolide
Purity: ≥97%(HPLC)
Packaging: 25
Price: $1029
Updated: 2021/12/16

Usbiological

Product number: N2567-38
Product name: Nimbolide
Packaging: 5mg
Price: $440
Updated: 2021/12/16

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nimbolide Chemical Properties,Usage,Production

Chemical Properties

Light Beige Solid

Uses

Nimbolide, a natural triterpenoid present in the edible parts of the neem tree (Azadirachta indica), was found to be growth-inhibitory in human colon carcinoma HT-29 cells. Nimbolide treatment of cells at 2.5 - 10 μM resulted in moderate to very strong growth inhibition.

storage

Store at -20°C

nimbolide Preparation Products And Raw materials

Raw materials

Preparation Products

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nimbolide Suppliers

Canada 2 CHINA 72 India 2 United Kingdom 1 United States 7 Global 84

Wuhan Acumen Bio-Technology Co.,ltd

Tel: 027-027-16602739303 16602739303
Email: 673003916@qq.com
Country: China
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J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
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Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32321
Advantage: 50

ChemStrong Scientific Co.,Ltd

Tel: 0755-0755-66853366 13670046396
Fax: 0755-28363542
Email: sales@chem-strong.com
Country: China
ProdList: 18070
Advantage: 56

Finetech Industry Limited

Tel: 027-87465837 19945049750
Fax: 027-8777-2287
Email: sales@finetechnology-ind.com
Country: China
ProdList: 9648
Advantage: 58

Hangzhou J&H Chemical Co., Ltd.

Tel: 0571-+86-571-87396432
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Email: sales@jhechem.com
Country: China
ProdList: 11578
Advantage: 59

Wuhan ChemFaces Biochemical Co., Ltd.

Tel: 18607101326 15172504745
Fax: +86-27-84254680
Email: aileen@chemfaces.com
Country: China
ProdList: 6905
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Shanghai Synchem Pharma Co., ltd

Tel: 21-619849051-1 18521059765
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Country: China
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Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
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Advantage: 58

Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 18892239720
Fax: 010-60605840
Email: psaitong@jm-bio.com
Country: China
ProdList: 12306
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25990-37-8, nimbolideRelated Search:

5,7-Dihydrox -4'-methoxyisoflavone Indacaterol INDACONITINE 4-Hexanolide Toosendanin (CIS)-8-METHYLNON-6-ENOIC ACID AZELAIC ACID MONOMETHYL ESTER nimbolide 4-ACETYL-4-METHYLHEPTANEDIOIC ACID 4-HYDROXYMETHYL-4-METHYL-CYCLOHEX-2-ENONE

nimbolide

(17R)-7α,15β:21,23-Diepoxy-6α-hydroxy-4,8-dimethyl-1-oxo-11-methoxycarbonyl-18,24-dinor-11,12-seco-5α-chola-2,13,20,22-tetrene-4α-carboxylic acid γ-lactone

NSC 309909

2H,5H-Cyclopenta[d']naphtho[1,8-bc:2,3-b']difuran-6-acetic acid, 8-(3-furanyl)-2a,5a,6,6a,8,9,9a,10a,10b,10c-decahydro-2a,5a,6a,7-tetramethyl-2,5-dioxo-, methyl ester, (2aR,5aR,6S,6aR,8R,9aR,10aS,10bR,10cR)-

methyl [(2aR,5aR,6S,6aR,8R,9aR,10aS,10bR,10cR)-8-furan-3-yl-2a,5a,6a,7-tetramethyl-2,5-dioxo-2a,5a,6,6a,8,9,9a,10a,10b,10c-decahydro-2H,5H-cyclopenta[d]naphtho[2,3-b:1,8-b''c'']difuran-6-yl]acetate

Nimbolide (25 mg)

Nimbolide, CyclinA and ERK1/2 inhibitor

25990-37-8

C27H30O72

Heterocycles

Intermediates & Fine Chemicals

Pharmaceuticals