Methyl vanillate

Product Name: Methyl vanillate
CAS No.: 3943-74-6
Chemical Name: Methyl vanillate
Synonyms: 62-65oC;Methylevanillate;METHYL VANILLATE;MethylVanillate>TIMTEC-BB SBB008281;RARECHEM AL BF 0101;Eugenol Impurity 26;Methyl vanillate 99%;Vanillic acid methyl;Methyl vanillic acid
CBNumber: CB1138142
Molecular Formula: C9H10O4
Formula Weight: 182.17
MOL File: 3943-74-6.mol

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Methyl vanillate Property

Melting point:: 64-67 °C (lit.)
Boiling point:: 285-287 °C (lit.)
Density: 1.2481 (rough estimate)
refractive index: 1.4500 (estimate)
Flash point:: 285-287°C
storage temp.: Sealed in dry,Room Temperature
solubility: Soluble in chloroform and methanol.
form: Powder and Granules
pka: 8.36±0.18(Predicted)
color: Pale yellow to beige
Odor: at 100.00 %. warm spicy vanilla guaiacol phenolic carnation
Odor Type: vanilla
biological source: synthetic
BRN: 1369113
InChIKey: BVWTXUYLKBHMOX-UHFFFAOYSA-N
LogP: 2.231 (est)
CAS DataBase Reference: 3943-74-6(CAS DataBase Reference)
NIST Chemistry Reference: Benzoic acid, 4-hydroxy-3-methoxy-, methyl ester(3943-74-6)
EPA Substance Registry System: Benzoic acid, 4-hydroxy-3-methoxy-, methyl ester (3943-74-6)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36-24/25
WGK Germany: 3
RTECS: DH2430000
TSCA: Yes
HS Code: 29189900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 138126
Product name: Methyl vanillate
Purity: 99%
Packaging: 25g
Price: $122.55
Updated: 2025/07/31

Sigma-Aldrich

Product number: 138126
Product name: Methyl vanillate
Purity: 99%
Packaging: 100g
Price: $490
Updated: 2025/07/31

TCI Chemical

Product number: M1738
Product name: Methyl Vanillate
Purity: >98.0%(GC)
Packaging: 5g
Price: $31
Updated: 2025/07/31

TCI Chemical

Product number: M1738
Product name: Methyl Vanillate
Purity: >98.0%(GC)
Packaging: 25g
Price: $100
Updated: 2025/07/31

TRC

Product number: M338490
Product name: Methyl Vanillate
Packaging: 250g
Price: $645
Updated: 2021/12/16

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Methyl vanillate Chemical Properties,Usage,Production

Chemical Properties

pale yellow to beige powder and granules

Uses

Methyl vanillate is used to investigate the volatile compounds of heather honeys from Calluna vulgaris and Erica arborea.

Uses

Methyl Vanillate maintains antimicrobial properties due to the phenylpropanoid moiety in the structure.

Definition

ChEBI: Methyl vanillate is a benzoate ester that is the methyl ester of vanillic acid. It has a role as an antioxidant and a plant metabolite. It is a benzoate ester, a member of phenols and an aromatic ether. It is functionally related to a vanillic acid.

General Description

Methyl vanillate is a volatile compound present in cloudberries (Rubus Chamaemorus.). Methyl vanillate can be synthesized from vanillic acid. Methyl vanillate has been identified in foods such as cow's milk and beer.

Biological Activity

Methyl vanillate, one of the ingredients in Hovenia dulcis Thunb, is a Wnt/β-catenin pathway activator. A benzoate ester that is the methyl ester of vanillic acid. It has a role as an antioxidant and a plant metabolite.

References

[1] PU-HYEON CHA. Hovenia dulcis Thunb extract and its ingredient methyl vanillate activate Wnt/β-catenin pathway and increase bone mass in growing or ovariectomized mice.[J]. PLoS ONE, 2014: e85546. DOI:10.1371/journal.pone.0085546.
[2] ADRIANO DE SOUZA PESSOA . The dimerization of methyl vanillate improves its effect against breast cancer cells via pro-oxidant effect[J]. Chemico-Biological Interactions, 2022, 361: Article 109962. DOI:10.1016/j.cbi.2022.109962.
[3] CHRONG-SHYUA CHU P. D R C Liao. A formal synthesis of (+/-)-reserpine from methyl vanillate[J]. Chemical Communications, 1996, 1 1: 1537-1538. DOI:10.1039/CC9960001537.
[4] JUAN TIAN. Ethyl acetate as a co-solvent and sacrificial ester in the aluminum triiodide promoted chemoselective demethylation of methyl vanillate[J]. Tetrahedron Letters, 2017, 58 36: Pages 3522-3524. DOI:10.1016/j.tetlet.2017.07.089.

Methyl vanillate Preparation Products And Raw materials

Raw materials

Preparation Products

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Methyl vanillate Suppliers

Americas 1 Belgium 2 Canada 1 China 326 Europe 3 Germany 7 Hungary 1 India 19 Japan 3 Slovakia 1 South Korea 1 Switzerland 3 Ukraine 1 United Kingdom 15 United States 45 USA 1 Global 430

Shandong Hydrocarbon Bio-Chemical Co. LTD

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J & K SCIENTIFIC LTD.

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PharmaBlock Sciences (Nanjing),Inc.

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Meryer (Shanghai) Chemical Technology Co., Ltd.

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INTATRADE GmbH

Tel: +49 3493/605464
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Country: Germany
ProdList: 3572
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View Lastest Price from Methyl vanillate manufacturers

Hebei Chuanghai Biotechnology Co., Ltd

Product: Methyl vanillate 3943-74-6
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-11-29

Hebei Zhuanglai Chemical Trading Co Ltd

Product: Methyl vanillate 3943-74-6
Price: US $55.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20 tons
Release date: 2024-11-21

Hebei Chuanghai Biotechnology Co,.LTD

Product: Methyl vanillate 3943-74-6
Price: US $5.00-2.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10000kg
Release date: 2024-08-21

3943-74-6, Methyl vanillateRelated Search:

4-Methoxybenzoic acid POLY(METHYL ACRYLATE) Salicylic acid Acetonitrile 3-Hydroxybenzoic acid METHYL LAURATE FATTY ACID METHYL ESTER MIX C8-C22 Basic Violet 1 Methyl cinnamate METHYL OCTADEDANOATE Kresoxim-methyl Methanol Methyl benzoate Methyl acrylate Methyl dihydrojasmonate 4-Hydroxybenzoic acid Methyl methoxyacetate Dimethyl oxalate

Methyl vanillate 99%

4-Hydroxy-3-methoxybenzoic Acid Methyl Ester Methyl 4-Hydroxy-3-methoxybenzoate Vanillic Acid Methyl Ester

4-HYDROXY-3-METHOXYBENZOIC ACID METHYL ESTER

Methylevanillate

METHYL 4-HYDROXY-3-METHOXYBENZOATE

METHYL VANILLATE

METHYL 3-METHOXY-4-HYDROXYBENZOATE

RARECHEM AL BF 0101

TIMTEC-BB SBB008281

3-Methoxy-4-hydroxybenzoic acid methyl ester

Vanillic acid methyl

Methyl vanillate, 99% 25GR

Methyl vanillate, 99% 5GR

Vanillic Acid Methyl Ester Methyl 4-Hydroxy-3-methoxybenzoate 4-Hydroxy-3-methoxybenzoic Acid Methyl Ester

Methyl vanillate SynonyMs Methyl 4-hydroxy-3-Methoxybenzoate

VANILLIC ACID METHYL ESTER

METHYL VANILLATE (CARNALINE)

METHYL VANILLATE 99+%

4-Hydroxy-3-methoxybenzoic acid methyl ester (methyl vanillate)

4-hydroxy-3-methoxy-benzoicacimethylester

Benzoicacid,4-hydroxy-3-methoxy-,methylester

Methyl ester of 4-hydroxy-3-methoxybenzoic acid

Methyl4-hydroxy-3-mehtoxybenzoate

4-HYDROXY-3-METHOXYBENZOIC ACID METHYL ESTER 98%

methylvanillate,methyl4-hydroxy-3-methoxybenzoate

62-65oC

4-hydroxy-3-methoxy Methy Benzoate

Vanillic acid, methyl este

MethylVanillate&gt

Eugenol Impurity 26

Factory Supply Hot Sale High Quality Methyl vanillate CAS 3943-74-6

Methyl vanillic acid

3943-74-6

HOC6H3OCH3CO2CH3

Esters

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C8 to C9

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FINE Chemical & INTERMEDIATES

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C8 to C9

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