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VICENIN

Product Name
VICENIN
CAS No.
23666-13-9
Chemical Name
VICENIN
Synonyms
Vicenin-2;Apigenin 6,8-di-C-glucoside;Apigenin 6,8-C-diglucoside;Vicenin-II;Vicenin II-RM;Glucosylapigenin;Apigenin 6,8-diglucoside;Vicenin 2, 10 mM in DMSO;6,8-Di-C-β-D-glucopyranosylapigenin;Apigenin 6,8-C-di-β-D-glucopyranoside
CBNumber
CB11431064
Molecular Formula
C27H30O15
Formula Weight
594.52
MOL File
23666-13-9.mol
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VICENIN Property

Melting point:
>250 °C (decomp)
Boiling point:
974.7±65.0 °C(Predicted)
Density 
1.758±0.06 g/cm3(Predicted)
storage temp. 
Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility 
Methanol (Slightly, Heated, Sonicated), DMSO (Slightly)
pka
5.68±0.40(Predicted)
form 
Solid
color 
Light Yellow to Yellow
Water Solubility 
sparingly soluble in water
Stability:
Hygroscopic
InChIKey
FIAAVMJLAGNUKW-YFDIWHCFNA-N
SMILES
OC[C@H]1O[C@@H](C2=C(O)C([C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)=C4C(C(C=C(C5=CC=C(O)C=C5)O4)=O)=C2O)[C@H](O)[C@@H](O)[C@@H]1O
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Safety

WGK Germany 
3
Storage Class
11 - Combustible Solids
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PHL83000
Product name
Vicenin II
Purity
phyproof? Reference Substance
Packaging
10MG
Price
$690
Updated
2026/03/19
Sigma-Aldrich
Product number
03980585
Product name
Vicenin 2
Purity
primary pharmaceutical reference standard
Packaging
10mg
Price
$998
Updated
2026/03/19
TRC
Product number
V757028
Product name
Vicenin 2
Packaging
0.5mg
Price
$50
Updated
2021/12/16
Usbiological
Product number
301103
Product name
Vicenin-II
Packaging
10mg
Price
$490
Updated
2021/12/16
Biosynth Carbosynth
Product number
FV74184
Product name
Vicenin 2
Packaging
25mg
Price
$500
Updated
2021/12/16
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VICENIN Chemical Properties,Usage,Production

Chemical Properties

White crystalline powder, soluble in organic solvents such as methanol, ethanol, and DMSO, derived from Desmodium sibiricum.

Uses

Vicenin 2 (CAS# 23666-13-9) is a biologically active compound extracted from Hypericum salsugineum and displays significant anti-cancer effects on breast carcinoma cell lines.

Definition

ChEBI: Isovitexin 8-C-beta-glucoside is a C-glycosyl compound that is isovitexin in which the hydrogen at position 8 is replaced by a beta-D-glucosyl residue. It has a role as a metabolite. It is a trihydroxyflavone and a C-glycosyl compound. It is functionally related to an isovitexin.

Synthesis

A method for simultaneous isolation of schaftoside, vicenin-2, and ecdysterone from Sagina japonica:
1. Ethanol extraction, followed by solvent partitioning to obtain an n-butanol extract.
2. The extract is fractionated on an AB-8 macroporous resin column, eluting with 50% ethanol to enrich the target compounds.
3. The enriched fraction is separated on an ODS reversed-phase column, yielding three preliminary fractions.
4. Impure vicenin-2 and schaftoside are further purified separately on silica gel columns.

in vivo

Vicenin 2 (50 mg/kg; orally administration; for 7 days) effectively reduces the MPO activity, attenuates the expression of pro-inflammatory cytokines and key inflammatory markers, in DSS-induced colitis mice[3].

Animal Model:Male C57BL/6J mice (25 g) treated with Dextran sulfate sodium (DSS)[3]
Dosage:50 mg/kg
Administration:Orally administration; for 7 days
Result:Effectively suppressed DSS-induced colitis by attenuating expressions of key inflammatory mediators.

VICENIN Preparation Products And Raw materials

Raw materials

Preparation Products

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VICENIN Suppliers

China 164 India 2 United Kingdom 2 United States 13 USA 1 Global 182
Jiangxi Baicaoyuan Biotechnology Co. , Ltd.
Tel
0791-82165230 17707911324
Email
1459265273@qq.com
Country
China
ProdList
1387
Advantage
58
Chengdu Nakeli Biotechnology Co., Ltd.
Tel
028-61983833 19138982515
Fax
3265827856
Email
3265827856@qq.com
Country
China
ProdList
1581
Advantage
58
Dalian Meilun Biotech Co., Ltd.
Tel
0411-62910999 13889544652
Email
sales@meilune.com
Country
China
ProdList
4790
Advantage
58
ShangHai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847 13636370518
Fax
021-55068248
Email
shyysw007@163.com
Country
China
ProdList
5000
Advantage
60
Chengdu Biopurify Phytochemicals Ltd.
Tel
+86-028-82633397 18982077548
Fax
+86-28-82633165
Email
cwb1@biopurify.cn
Country
China
ProdList
2376
Advantage
60
Shanghai Winherb Medical Technology Co., Ltd.
Tel
17301719108 13341702378
Fax
QQ：190129269
Email
winherb@126.com
Country
China
ProdList
1245
Advantage
58
UHN Shanghai Research & Development Co., Ltd.
Tel
021-58958002 18930822973
Fax
+86 (21) 5895-8628
Email
sales@uhnshanghai.com
Country
China
ProdList
998
Advantage
58
Shanghai Tauto Biotech Co., Ltd.
Tel
021-51320588
Fax
0086-21-51320502
Email
tauto@tautobiotech.com
Country
China
ProdList
3988
Advantage
66
TargetMol Chemicals Inc.
Tel
021-021-33632979 15002134094
Fax
021-33632979
Email
marketing@targetmol.com
Country
China
ProdList
8000
Advantage
58
Cheng Du Pufeide Biotechnology Co., Ltd.
Tel
028-82610909 13388174823
Fax
8171-1798
Email
scglp@glp-china.com
Country
China
ProdList
1064
Advantage
58
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View Lastest Price from VICENIN manufacturers

Shanghai Standard Technology Co., Ltd.
Product
Vicenin-2 23666-13-9
Price
US $0.00/mg
Min. Order
20mg
Purity
≥98%(HPLC)
Supply Ability
10 g
Release date
2020-03-18

23666-13-9, VICENINRelated Search:

4',5-DIHYDROXY-7-METHOXYFLAVONE GARDENIN B MOSLOFLAVONE APIGENIN-6-ARABINOSIDE-8-GLUCOSIDE MEDICAGOL Naringenin PONCIRIN APIGENIN-6-GLUCOSIDE-8-ARABINOSIDE 6-beta-D-Glucopyranosyl-8-beta-D-xylopyranosylapigenin Quercetin-7-O-β-D-glucopyranoside Naringenin 7-O-β-D-Glucuronide (Mixture of Diastereomers) 2-(3,4-Dihydroxyphenyl)-8-(2-O-beta-L-galactopyranosyl-beta-D-glucopyranosyl)-5,7-dihydroxy-4H-1-Benzopyran-4-one hydroxygenkwanin Xylitol Apigenin Apigenin 7-glucoside Apigenin-D5 APIGENIN-7-GLUCURONIDE

  • 2-(4-Hydroxyphenyl)-5,7-dihydroxy-6,8-bis(β-D-glucopyranosyl)-4H-1-benzopyran-4-one
  • 6,8-Di(β-D-glucopyranosyl)-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
  • Apigenin 6,8-C-diglucoside
  • 5,7-Dihydroxy-2-(4-hydroxyphenyl)-6,8-bis[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]chromen-4-one
  • Vicenin-2
  • Vicenin-II
  • 4H-1-Benzopyran-4-one,6,8-di-b-D-glucopyranosyl-5,7-dihydroxy-2-(4-hydroxyphenyl)-
  • 6,8-Di-C-β-D-glucopyranosylapigenin
  • Apigenin 6,8-C-di-β-D-glucopyranoside
  • Apigenin 6,8-diglucoside
  • Apigenin 6,8-di-C-glucoside (Vicenin-2)
  • 4H-1-Benzopyran-4-one, 6,8-di-β-D-glucopyranosyl-5,7-dihydroxy-2-(4-hydroxyphenyl)-
  • Apigenin 6,8-di-C-glucoside
  • Glucosylapigenin
  • 5,7-Dihydroxy-2-(4-hydroxyphenyl)-6,8-bis((2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)-4H-chromen-4-one
  • Vicenin II-RM
  • Vicenin 2, 10 mM in DMSO
  • 23666-13-9