Apigenin-D5
- Product Name
- Apigenin-D5
- CAS No.
- 263711-74-6
- Chemical Name
- Apigenin-D5
- Synonyms
- Apigenin-D5;Apigenin-d5 (Major);Pelargidenon 1449-d5;[3,6,8,35d5]-Apigenin;4',5,7-Trihydroxyflavone-d5;5,7-Dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one-d5;4H-1-Benzopyran-4-one-3,6,8-d3, 5,7-dihydroxy-2-(4-hydroxyphenyl-3,5-d2)-;3,6,8-trideuterio-2-(3,5-dideuterio-4-hydroxyphenyl)-5,7-dihydroxychromen-4-one
- CBNumber
- CB71121213
- Molecular Formula
- C15H5D5O5
- Formula Weight
- 0
- MOL File
- 263711-74-6.mol
Apigenin-D5 Property
- Melting point:
- 345-350°C
- storage temp.
- -20°C Freezer
- solubility
- DMSO (Slightly), Ethanol (Slightly, Heated), Methanol (Slightly)
- form
- Solid
- color
- Pale Yellow to Yellow
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 22106
- Product name
- Apigenin-d5
- Purity
- ≥99% deuterated forms (d1-d5); ≤1% d0
- Packaging
- 500μg
- Price
- $145
- Updated
- 2024/03/01
- Product number
- 22106
- Product name
- Apigenin-d5
- Purity
- ≥99% deuterated forms (d1-d5); ≤1% d0
- Packaging
- 1mg
- Price
- $276
- Updated
- 2024/03/01
- Product number
- 002799
- Product name
- Apigenin-d5
- Packaging
- 1mg
- Price
- $425
- Updated
- 2021/12/16
- Product number
- A726502
- Product name
- Apigenin-d5(Major)
- Packaging
- 10mg
- Price
- $1155
- Updated
- 2021/12/16
- Product number
- A726502
- Product name
- Apigenin-d5(Major)
- Packaging
- 1mg
- Price
- $145
- Updated
- 2021/12/16
Apigenin-D5 Chemical Properties,Usage,Production
Description
Apigenin-d5 is an internal standard for the quantificaiton of apigenin by GC- or LC-MS. Apigenin is a flavonoid compound found in many fruits and vegetables that selectively inhibits casein kinase 2 (CK2). Apigenin inhibits CK2 activity in the renal cortex with an IC50 value of 30 μM to improve renal function in a rat model of glomerulonephritis. CK2 inhibition by 20 μM apigenin decreases the degradation of IκBα and down-regulates NF-κB levels in WEHI-231 cells. Apigenin, at 5 μM, is a potent inhibitor of the synthesis of the inflammatory mediators nitric oxide and prostaglandin E2, reducing inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) expression by 56% and 64%, respectively, in the macrophage cell line J774A.1.
Chemical Properties
Pale Yellow Crystalline Solid
Uses
The labelled aglucon of apiin and of apigenin-7-glucoside
Apigenin-D5 Preparation Products And Raw materials
Raw materials
Preparation Products
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