ChemicalBook > CAS DataBase List > Apigenin-D5

Apigenin-D5

Product Name
Apigenin-D5
CAS No.
263711-74-6
Chemical Name
Apigenin-D5
Synonyms
Apigenin-D5;Apigenin-d5 (Major);Pelargidenon 1449-d5;[3,6,8,35d5]-Apigenin;4',5,7-Trihydroxyflavone-d5;5,7-Dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one-d5;4H-1-Benzopyran-4-one-3,6,8-d3, 5,7-dihydroxy-2-(4-hydroxyphenyl-3,5-d2)-;3,6,8-trideuterio-2-(3,5-dideuterio-4-hydroxyphenyl)-5,7-dihydroxychromen-4-one
CBNumber
CB71121213
Molecular Formula
C15H5D5O5
Formula Weight
0
MOL File
263711-74-6.mol
More
Less

Apigenin-D5 Property

Melting point:
345-350°C
storage temp. 
-20°C Freezer
solubility 
DMSO (Slightly), Ethanol (Slightly, Heated), Methanol (Slightly)
form 
Solid
color 
Pale Yellow to Yellow
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

More
Less

N-Bromosuccinimide Price

Cayman Chemical
Product number
22106
Product name
Apigenin-d5
Purity
≥99% deuterated forms (d1-d5); ≤1% d0
Packaging
500μg
Price
$145
Updated
2024/03/01
Cayman Chemical
Product number
22106
Product name
Apigenin-d5
Purity
≥99% deuterated forms (d1-d5); ≤1% d0
Packaging
1mg
Price
$276
Updated
2024/03/01
Usbiological
Product number
002799
Product name
Apigenin-d5
Packaging
1mg
Price
$425
Updated
2021/12/16
TRC
Product number
A726502
Product name
Apigenin-d5(Major)
Packaging
10mg
Price
$1155
Updated
2021/12/16
TRC
Product number
A726502
Product name
Apigenin-d5(Major)
Packaging
1mg
Price
$145
Updated
2021/12/16
More
Less

Apigenin-D5 Chemical Properties,Usage,Production

Description

Apigenin-d5 is an internal standard for the quantificaiton of apigenin by GC- or LC-MS. Apigenin is a flavonoid compound found in many fruits and vegetables that selectively inhibits casein kinase 2 (CK2). Apigenin inhibits CK2 activity in the renal cortex with an IC50 value of 30 μM to improve renal function in a rat model of glomerulonephritis. CK2 inhibition by 20 μM apigenin decreases the degradation of IκBα and down-regulates NF-κB levels in WEHI-231 cells. Apigenin, at 5 μM, is a potent inhibitor of the synthesis of the inflammatory mediators nitric oxide and prostaglandin E2, reducing inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) expression by 56% and 64%, respectively, in the macrophage cell line J774A.1.

Chemical Properties

Pale Yellow Crystalline Solid

Uses

The labelled aglucon of apiin and of apigenin-7-glucoside

Apigenin-D5 Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

Apigenin-D5 Suppliers

Toronto Research Chemicals
Tel
--
Fax
--
Email
info@trc-canada.com
Country
Canada
ProdList
6038
Advantage
71

263711-74-6, Apigenin-D5Related Search:


  • Apigenin-D5
  • [3,6,8,35d5]-Apigenin
  • 4',5,7-Trihydroxyflavone-d5
  • 5,7-Dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one-d5
  • Pelargidenon 1449-d5
  • Apigenin-d5 (Major)
  • 3,6,8-trideuterio-2-(3,5-dideuterio-4-hydroxyphenyl)-5,7-dihydroxychromen-4-one
  • 4H-1-Benzopyran-4-one-3,6,8-d3, 5,7-dihydroxy-2-(4-hydroxyphenyl-3,5-d2)-
  • 263711-74-6
  • C15H5D5O5
  • Isotope Labelled Compounds
  • Inhibitors
  • Isotope Labeled Compounds