PROPYL LAURATE

PROPYL LAURATE Property

Melting point:

4.2°C (estimate)

Boiling point:

285.23°C (estimate)

Density 

0.86 g/mL at 25 °C(lit.)

refractive index 

1.4335

storage temp. 

Sealed in dry,Room Temperature

solubility 

Chloroform (Slightly), Methanol (Slightly)

form 

Oil

color 

Colourless

LogP

6.110

CAS DataBase Reference

3681-78-5

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

PROPYL LAURATE Chemical Properties,Usage,Production

Uses

Propyl dodecanoate is an ester product.

Synthesis

The general procedure for the synthesis of propyl dodecanoate from n-propanol and vinyl laurate is as follows: enzymatic synthesis in a 50 mL high pressure reactor. The reactor was equipped with a pressure reading controller and a JASCO-PU-2080-CO2 plus regulator. First, a predetermined amount of vinyl laurate was added to the reactor, followed by a predetermined amount of n-propanol. Next, a fixed amount of PVA/CHI lipase was added to initiate the reaction, followed by sealing the reactor and assembling it into an SC-CO2 high pressure reaction system. Liquid SC-CO2 was pumped into the reactor at a flow rate of 3.5 mL/min. The reaction was carried out for a predetermined time at a specific pressure (MPa) and temperature (°C) set by the RSM software. Upon completion of the reaction, the SC-CO2 pressure was slowly released through a 50°C thermostatic limiter to allow the residual material inside the reactor to flow out with the CO2. The reaction products were subsequently analyzed by Perkin-Elmer Clarus-400 gas chromatography (GC) equipped with a flame ionization detector (FID) and a capillary column.The oven temperature program for the GC was to maintain an initial temperature of 90 °C for 4 min, and then increase the temperature at a rate of 10 °C/min to 240 °C. The GC was then operated at a constant temperature of 50 °C, and the temperature was increased by a Shimadzu QC. In addition, the products were further confirmed by gas chromatography-mass spectrometry (GC-MS) on a Shimadzu QP-2010 instrument.

References

[1] Process Biochemistry, 2015, vol. 50, # 8, p. 1224 - 1236