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Protoporphyrin IX dimethyl ester

Product Name
Protoporphyrin IX dimethyl ester
CAS No.
5522-66-7
Chemical Name
Protoporphyrin IX dimethyl ester
Synonyms
Protoporphyrin dimethyl;dimethyl protoporphyrin IX;Protoporphyrin IX diMethyl es;Protoporphyrin IX dimethyl ester;Dimethylprotoporphyrin IX dimethyl ester;Protoporphyrin IX dimethyl ester, ≥95%(HPLC);Protoporphyrin IX dimethyl ester ~90% (HPLC);PROTOPORPHYRIN IX DIMETHYL ESTER FROM*OX HEMIN;dimethyl 8,13-divinyl-3,7,12,17-tetramethyl-21h,23h-porphine-2,18-dipropionate;dimethyl 3,8,13,17-tetramethyl-7,12-divinyl-21H,23H-porphine-2,18-dipropionate
CBNumber
CB9497515
Molecular Formula
C36H38N4O4
Formula Weight
590.71
MOL File
5522-66-7.mol
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Protoporphyrin IX dimethyl ester Property

Melting point:
225-228 °C(lit.)
Boiling point:
1017.0±65.0 °C(Predicted)
Density 
1.220±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,2-8°C
solubility 
DMSO: soluble
form 
crystal
color 
purple
BRN 
381574
Stability:
Light Sensitive
InChIKey
WASRLAPXOHTNAX-MFBGAUBSSA-N
SMILES
C(C1=C(C2=CC3=NC(=CC4=C(C=C)C(C)=C(N4)C=C4C(C)=C(CCC(=O)OC)C(=N4)C=C1N2)C(C)=C3C=C)C)CC(=O)OC |c:7,t:3,18,32|
EPA Substance Registry System
21H,23H-Porphine-2,18-dipropanoic acid, 7,12-diethenyl-3,8,13,17-tetramethyl-, dimethyl ester (5522-66-7)
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Safety

WGK Germany 
3
8-10-23
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H303May be harmfulif swallowed

H320Causes eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
09626
Product name
Protoporphyrin IX dimethyl ester
Purity
~90% (HPLC)
Packaging
100mg
Price
$187.15
Updated
2025/07/31
TCI Chemical
Product number
D6148
Product name
Protoporphyrin IX Dimethyl Ester
Packaging
100MG
Price
$183
Updated
2025/07/31
Strem Chemicals
Product number
07-1850
Product name
Protoporphyrin IX, dimethyl ester
Packaging
100mg
Price
$87
Updated
2024/03/01
Strem Chemicals
Product number
07-1850
Product name
Protoporphyrin IX, dimethyl ester
Packaging
500mg
Price
$308
Updated
2024/03/01
TRC
Product number
P838900
Product name
Protoporphyrin IX dimethyl ester
Packaging
100mg
Price
$65
Updated
2021/12/16
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Protoporphyrin IX dimethyl ester Chemical Properties,Usage,Production

Chemical Properties

Protoporphyrin IX dimethyl ester is a dark purple powder. Solubility: soluble in DMSO, acetone, and chloroform.

Uses

Protoporphyrin IX Dimethyl Ester is a derivative of Protoporphyrin IX (P839138), which is an important precursor to biologically essential prosthetic groups such as heme, cytochrome c, and chlorophylls.

Definition

ChEBI: Dimethylprotoporphyrin IX dimethyl ester is a member of porphyrins.

Purification Methods

The crude dimethyl ester (1g) in CHCl3 (200 mL) is mixed with pet ether (b 70-90o, 600mL), and any porphyrin (m > 260o) which is insoluble in this mixture is filtered off. The filtrate is passed through a column of CaCO3 [from CaCO3 (130g) which is kept overnight in a mixture of CHCl3/pet ether (b 70-90o, 1:3), and the slurry is poured into a glass tube (2.5 x 26cm) to form the column]. After all the filtrate is applied, the column is eluted with a solution of CHCl3/pet ether (b 70-90o, 1:3). All the coloured eluates are collected, evaporated at room temperature in a vacuum to give a residue (0.8g), m 208-211o. The residue (0.8g) in CHCl3 (66mL) is heated briefly to its boiling point, then boiling MeOH (198mL) is added immediately to it. The mixture is allowed to cool to room temperature, refrigerated for 2days and the solid is filtered off. The solid is washed on the filter funnel with CHCl3/MeOH (1:9, 50mL) and dried at 50o/vacuum (yield 0.62-0.66g). It can also be recrystallised by dissolving in as little hot dry *C6H6 as possible and left overnight at 20o, m 228-230o. It has also been purified by dissolving (0.4g) in CHCl3 (33mL) by boiling for a few minutes, then diluting with boiling MeOH (100mL) and refrigerating for 2days. The crystals are collected, washed with CHCl3/MeOH (1:9) and dried at 50o in a vacuum (yield 0.3g). The UV has max at 631, 576, 541, 506 and 407nm in CHCl3 and 601, 556 and 406nm in 25% HCl. [Ramsey Biochemical Preparations 3 39 1953, Beilstein 26 III/IV 3052.]

Protoporphyrin IX dimethyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

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Protoporphyrin IX dimethyl ester Suppliers

Shanghai Xianhui Pharmaceutical Co., Ltd.
Tel
13564796979
Fax
86 21 67792654
Email
shxh2006@aliyun.com
Country
China
ProdList
32
Advantage
62
Chengdu Aslee Biopharmaceuticals, Inc
Tel
028-85305008 02885305008
Fax
4000210878-186
Email
2306208234@qq.com
Country
China
ProdList
1006
Advantage
50
Hangzhou FuRun Pharmaceutical Technology Co., Ltd
Tel
15658004993
Email
1900830611@qq.com
Country
China
ProdList
980
Advantage
58
NewCan Biotech Limited
Tel
+86-0571-86912261 +86-15658003402
Fax
311113
Email
sales@newcanbio.com
Country
China
ProdList
1391
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J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
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76
Chembest Research Laboratories Limited
Tel
+86-21-20908456
Fax
021-58180499
Email
sales@BioChemBest.com
Country
China
ProdList
6003
Advantage
61
Shandong Xiya Chemical Co., Ltd
Tel
4009903999 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18729
Advantage
57
Dalian Meilun Biotech Co., Ltd.
Tel
0411-62910999 13889544652
Email
sales@meilune.com
Country
China
ProdList
4747
Advantage
58
ShangHai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847 13636370518
Fax
021-55068248
Email
shyysw007@163.com
Country
China
ProdList
4999
Advantage
60
T&W GROUP
Tel
021-61551611 13296011611
Fax
+86 21-50676805
Email
contact@trustwe.com
Country
China
ProdList
9895
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View Lastest Price from Protoporphyrin IX dimethyl ester manufacturers

Hebei Chuanghai Biotechnology Co., Ltd
Product
Protoporphyrin IX dimethyl ester 5522-66-7
Price
US $10.00/KG
Min. Order
100KG
Purity
99%
Supply Ability
100 mt
Release date
2024-11-25
Shaanxi Dideu New Materials Co. Ltd
Product
Protoporphyrin IX dimethyl ester 5522-66-7
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
95.0%
Supply Ability
10000KGS
Release date
2024-11-11
Hebei Chuanghai Biotechnology Co,.LTD
Product
Protoporphyrin IX dimethyl ester 5522-66-7
Price
US $1.90/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 ton
Release date
2024-08-05

5522-66-7, Protoporphyrin IX dimethyl esterRelated Search:


  • Protoporphyrin IX dimethyl ester, ≥95%(HPLC)
  • methyl 3-[8,13-di(ethenyl)-18-(3-methoxy-3-oxo-propyl)-3,7,12,17-tetramethyl-22,23-dihydroporphyrin-2-yl]propanoate
  • methyl 3-[8,13-di(ethenyl)-18-(3-methoxy-3-oxopropyl)-3,7,12,17-tetramethyl-22,23-dihydroporphyrin-2-yl]propanoate
  • Protoporphyrin IX diMethyl es
  • 21H,23H-Porphine-2,18-dipropanoicacid, 7,12-diethenyl-3,8,13,17-tetraMethyl-, 2,18-diMethyl ester
  • ProtoporphyrinIX dimethyl ester,Dimethyl 8,13-divinyl-3,7,12,17-tetramethyl-21H,23H-porphine-2,18-dipropionate, Ooporpyhrin dimethyl ester
  • dimethyl 8,13-divinyl-3,7,12,17-tetramethyl-21h,23h-porphine-2,18-dipropionate
  • 7,12-diethenyl-3,8,13,17-tetramethyl-21H,23H-Porphine-2,18-dipropanoic acid- 2,18-dimethyl ester
  • Dimethylprotoporphyrin IX dimethyl ester
  • dimethyl protoporphyrin IX
  • Ooporpyhrin dimethyl ester, Dimethyl 8,13-divinyl-3,7,12,17-tetramethyl-21H,23H-porphine-2,18-dipropionate
  • 3,8,13,17-Tetramethyl-7,12-diethenyl-21H,23H-porphyrin-2,18-dipropionic acid dimethyl ester
  • 7,12-Diethenyl-3,8,13,17-tetramethyl-21H,23H-porphyrin-2,18-bis(propionic acid methyl) ester
  • Protoporphyrin dimethyl
  • 3-[18-(3-keto-3-methoxy-propyl)-3,7,12,17-tetramethyl-8,13-divinyl-22,23-dihydroporphin-2-yl]propionic acid methyl ester
  • dimethyl 3,8,13,17-tetramethyl-7,12-divinyl-21H,23H-porphine-2,18-dipropionate
  • PROTOPORPHYRIN IX DIMETHYL ESTER FROM*OX HEMIN
  • Protoporphyrin IX dimethyl ester
  • Protoporphyrin IX dimethyl ester ~90% (HPLC)
  • Dimethyl 3,3'-(3,8,13,17-tetramethyl-7,12-divinylporphyrin-2,18-diyl)dipropionate
  • 2,18-Dimethyl 7,12-diethenyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropanoate
  • 5522-66-7
  • porphine (porphyrin) ligand