8-Chloro-3-iodoimidazo[1,2-a]pyrazine
- Product Name
- 8-Chloro-3-iodoimidazo[1,2-a]pyrazine
- CAS No.
- 1049677-32-8
- Chemical Name
- 8-Chloro-3-iodoimidazo[1,2-a]pyrazine
- Synonyms
- 8-Chloro-3-iodoimidazo[1,2-a]pyrazine;Imidazo[1,2-a]pyrazine, 8-chloro-3-iodo-
- CBNumber
- CB11482006
- Molecular Formula
- C6H3ClIN3
- Formula Weight
- 279.47
- MOL File
- 1049677-32-8.mol
8-Chloro-3-iodoimidazo[1,2-a]pyrazine Property
- Density
- 2.34
Safety
- HS Code
- 2933998090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- OR321319
- Product name
- 8-Chloro-3-iodoimidazo[1,2-a]pyrazine
- Purity
- 97%
- Packaging
- 250mg
- Price
- $56
- Updated
- 2021/12/16
- Product number
- 3H32-M-0G
- Product name
- 8-Chloro-3-iodoimidazo[1,2-a]pyrazine
- Purity
- 97%
- Packaging
- 250mg
- Price
- $157
- Updated
- 2021/12/16
- Product number
- HCH0043750
- Product name
- 8-CHLORO-3-IODOIMIDAZO[1,2-A]PYRAZINE
- Purity
- 95.00%
- Packaging
- 0.25G
- Price
- $380
- Updated
- 2021/12/16
- Product number
- OR321319
- Product name
- 8-Chloro-3-iodoimidazo[1,2-a]pyrazine
- Packaging
- 1g
- Price
- $445
- Updated
- 2021/12/16
- Product number
- 3H32-M-0G
- Product name
- 8-Chloro-3-iodoimidazo[1,2-a]pyrazine
- Purity
- 97%
- Packaging
- 1g
- Price
- $527
- Updated
- 2021/12/16
8-Chloro-3-iodoimidazo[1,2-a]pyrazine Chemical Properties,Usage,Production
Chemical Properties
off-white solid
Biological Activity
8-Chloro-3-iodoimidazo[1,2-a]pyrazine has demonstrated broad-spectrum antibacterial activity at low concentration levels against both gram-positive and gram-negative bacteria. Its antimicrobial potency can be increased by structural modifications.
Synthesis
8-chloroimidazo[1,2-a]pyrazine (5.2 g, 33.9 mmol) and N-iodo-succinimide (NIS) (8 g, 35.6 mmol) were combined with DMF (34 ml). The reaction mixture was stirred at RT for 48 h. After that, the water was added to the suspension, and the solid was filtered, washed with water and MeOH, and dried under HV to afford 8-Chloro-3-iodoimidazo[1,2-a]pyrazine (7.17 g, 25.6 mmol, 75.8% yield).