BOC-2-ABZ-OH
- Product Name
- BOC-2-ABZ-OH
- CAS No.
- 68790-38-5
- Chemical Name
- BOC-2-ABZ-OH
- Synonyms
- BOC-ABZ-OH;BOC-ANT-OH;BOC-2-ABZ-OH;RARECHEM EM WB 0010;BOC-ANTHRANILIC ACID;BOC-AMINOBENZOIC ACID;N-BOC-ANTHRANILIC ACID;BOC-2-ABZ-OH USP/EP/BP;BOC-2-AMINOBENZOIC ACID;Boc-2-Abz-OH >=98.0% (T)
- CBNumber
- CB1150405
- Molecular Formula
- C12H15NO4
- Formula Weight
- 237.25
- MOL File
- 68790-38-5.mol
BOC-2-ABZ-OH Property
- Melting point:
- 153-156 °C (dec.)
- Boiling point:
- 328.6±25.0 °C(Predicted)
- Density
- 1.242±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,2-8°C
- pka
- 3.67±0.36(Predicted)
- Appearance
- White to off-white Solid
- BRN
- 2848891
- CAS DataBase Reference
- 68790-38-5
Safety
- Safety Statements
- 22-24/25
- WGK Germany
- 3
- HazardClass
- IRRITANT
- HS Code
- 29242990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H225Highly Flammable liquid and vapour
H302Harmful if swallowed
H315Causes skin irritation
H317May cause an allergic skin reaction
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 15297
- Product name
- Boc-2-Abz-OH
- Purity
- ≥98.0% (T)
- Packaging
- 10g
- Price
- $274
- Updated
- 2025/07/31
- Product number
- 264959
- Product name
- Boc-2-aminobenzoic acid
- Packaging
- 5g
- Price
- $366
- Updated
- 2021/12/16
- Product number
- B630025
- Product name
- BOC-2-ABZ-OH
- Packaging
- 50mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- FB48234
- Product name
- Boc-2-aminobenzoic acid
- Packaging
- 5G
- Price
- $83.6
- Updated
- 2021/12/16
- Product number
- 0626AC
- Product name
- Boc-2-aminobenzoicacid
- Packaging
- 5g
- Price
- $97
- Updated
- 2021/12/16
BOC-2-ABZ-OH Chemical Properties,Usage,Production
Chemical Properties
Beige powder
Uses
peptide synthesis
reaction suitability
reaction type: Boc solid-phase peptide synthesis
Synthesis
24424-99-5
118-92-3
68790-38-5
GENERAL STEPS: A mixed solution of o-aminobenzoic acid (25.0 g, 182 mmol, 1.0 eq.) and 1:1 THF:H2O (364 mL, 0.5 M) was added to a 1 L round bottom flask. The resulting non-homogeneous mixture was adjusted to pH 10 by dropwise addition of 2N NaOH aqueous solution. di-tert-butyl dicarbonate (43.7 g, 200 mmol, 1.1 eq.) was added to the reaction system, and the resulting homogeneous solution was stirred overnight at room temperature. Upon completion of the reaction, THF was removed by rotary evaporation.Subsequently, the remaining aqueous solution was adjusted to pH 4 by dropwise addition of 15% aqueous citric acid to the remaining aqueous solution so that 2-(N-tert-butoxycarbonylamino)benzoic acid precipitated as a white crystalline solid. The product was collected by vacuum filtration and dried in a vacuum oven to give a white crystalline solid (36.0 g, 88% yield).
References
[1] Chemistry Letters, 2010, vol. 39, # 11, p. 1127 - 1129
[2] Tetrahedron Letters, 2010, vol. 51, # 29, p. 3855 - 3858
[3] Tetrahedron Letters, 2006, vol. 47, # 38, p. 6739 - 6742
[4] Patent: WO2008/79719, 2008, A1. Location in patent: Page/Page column 51-52
[5] Patent: WO2007/120339, 2007, A1. Location in patent: Page/Page column 41-42
BOC-2-ABZ-OH Preparation Products And Raw materials
Raw materials
Preparation Products
BOC-2-ABZ-OH Suppliers
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View Lastest Price from BOC-2-ABZ-OH manufacturers
- Product
- Butyphthalide impurity 77 68790-38-5
- Price
- US $0.00-0.00/mg
- Min. Order
- 10mg
- Purity
- 0.98
- Supply Ability
- 5g
- Release date
- 2024-05-24
- Product
- BOC-2-ABZ-OH 68790-38-5
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20kg
- Release date
- 2018-08-14
- Product
- BOC-2-ABZ-OH 68790-38-5
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 1000KG
- Release date
- 2018-08-15