BOC-4-ABZ-OH

Product Name: BOC-4-ABZ-OH
CAS No.: 66493-39-8
Chemical Name: BOC-4-ABZ-OH
Synonyms: BOC-PABA;AKOS 90574;Boc-PABA-OH;BOC-4-ABZ-OH;BOC-P-ABZ-OH;RARECHEM EM WB 0012;N-Boc-4-aminobenzoic;BOC-4-ABZ-OH USP/EP/BP;BOC-4-AMINOBENZOIC ACID;BOC-P-AMINOBENZOIC ACID
CBNumber: CB3291568
Molecular Formula: C12H15NO4
Formula Weight: 237.25
MOL File: 66493-39-8.mol

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BOC-4-ABZ-OH Property

Melting point:: ~200 °C (dec.)
Boiling point:: 336.2±25.0 °C(Predicted)
Density: 1.242±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,2-8°C
solubility: soluble in Methanol
form: Powder
pka: 4.33±0.10(Predicted)
color: Beige
BRN: 2115614

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Safety

Risk Statements: 36/37/38
Safety Statements: 22-24/25
WGK Germany: 3
HazardClass: IRRITANT
HS Code: 29242990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 15299
Product name: Boc-4-Abz-OH
Purity: ≥98.0% (T)
Packaging: 5g
Price: $106
Updated: 2023/01/07

Sigma-Aldrich

Product number: 15299
Product name: Boc-4-Abz-OH
Purity: ≥98.0% (T)
Packaging: 50g
Price: $732
Updated: 2023/01/07

TCI Chemical

Product number: B3898
Product name: 4-(tert-Butoxycarbonylamino)benzoic Acid
Purity: >98.0%(HPLC)(T)
Packaging: 5g
Price: $33
Updated: 2025/07/31

TCI Chemical

Product number: B3898
Product name: 4-(tert-Butoxycarbonylamino)benzoic Acid
Purity: >98.0%(HPLC)(T)
Packaging: 25g
Price: $105
Updated: 2025/07/31

TRC

Product number: B690840
Product name: 4-(N-tert-Butoxycarbonyl)aminobenzoicAcid
Packaging: 5G
Price: $70
Updated: 2021/12/16

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BOC-4-ABZ-OH Chemical Properties,Usage,Production

Chemical Properties

Light brown powder

Uses

4-(N-tert-Butoxycarbonyl)aminobenzoic Acid is the tert-Butyloxycarbonyl group protected derivative of 4-Aminobenzoic Acid (A591500), an widely distributed B complex factor in nature.

reaction suitability

reaction type: Boc solid-phase peptide synthesis

Synthesis

24424-99-5

150-13-0

66493-39-8

General procedure for the synthesis of 4-(N-tert-butoxycarbonylamino)benzoic acid from di-tert-butyl dicarbonate and p-aminobenzoic acid: sodium hydroxide (1.46 g, 36.5 mmol) was added to a mixture of dioxane (70 mL) and water (35 mL) of 4-aminobenzoic acid (5.00 g, 36.5 mmol), followed by di-tert-butyl dicarbonate (11.9 g, 54.8 mmol). The reaction mixture was stirred at room temperature for 24 hours. Upon completion of the reaction, the solvent was removed by rotary evaporation and aqueous 3N hydrochloric acid was added slowly and dropwise to the residue to adjust the pH to 3. The precipitate precipitated was collected by filtration, washed with water and dried to afford the target product 4-(N-tert-butoxycarbonylamino)benzoic acid (8.28 g, 96% yield) as a white solid.

References

[1] Journal of Medicinal Chemistry, 2001, vol. 44, # 3, p. 441 - 452
[2] Journal of Catalysis, 2016, vol. 340, p. 344 - 353
[3] Tetrahedron Letters, 2003, vol. 44, # 37, p. 7103 - 7106
[4] Synthesis, 2005, # 7, p. 1061 - 1068
[5] Chemistry - A European Journal, 2003, vol. 9, # 2, p. 557 - 560

BOC-4-ABZ-OH Preparation Products And Raw materials

Raw materials

Preparation Products

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BOC-4-ABZ-OH Suppliers

Americas 1 Belgium 1 Canada 1 China 134 Europe 1 France 2 Germany 7 India 6 Japan 4 Switzerland 1 The Netherlands 1 Ukraine 1 United Kingdom 8 United States 31 Global 199

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
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Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006356688 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
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Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30123
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TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24529
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Energy Chemical

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Fax: 021-58436166
Email: sales8178@energy-chemical.com
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Wuhan Chemwish Technology Co., Ltd

Tel: 86-027-67849912
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Email: sales@chemwish.com
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ProdList: 35896
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Shanghai Sinch Parmaceuticals Tech. Co. Ltd.

Tel: +86-21-54098501
Fax: +86-21-54096319
Email: sales@sinch.com.cn
Country: China
ProdList: 11598
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Accela ChemBio Co.,Ltd.

Tel: 021-50795510 4000665055
Fax: 021-50795055
Email: sales@accelachem.com
Country: China
ProdList: 11035
Advantage: 64

Nanjing Chemlin Chemical Co., Ltd

Tel: 025-83697070
Fax: +86-25-83453306
Email: info@chemlin.com.cn
Country: China
ProdList: 15883
Advantage: 64

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42934
Advantage: 64

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View Lastest Price from BOC-4-ABZ-OH manufacturers

Career Henan Chemical Co

Product: BOC-4-ABZ-OH 66493-39-8
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: Customized
Release date: 2019-12-17

66493-39-8, BOC-4-ABZ-OHRelated Search:

4-Aminobenzoic acid BOC-3-ABZ-OH,BOC-M-ABZ-OH BOC-2-ABZ-OH BOC-4-ABZ-OH BOC-4-AMINO-3-METHOXYBENZOIC ACID BOC-4-ABZ-OSU 3-AMINO-4-TERT-BUTOXYCARBONYLAMINO-BENZOIC ACID TERT-BUTYL 4-(METHOXYCARBONYL)-3-METHOXYPHENYLCARBAMATE N-BOC-4-AMINO-2-CHLOROBENZOIC ACID N-BOC-4-(METHYLAMINO)BENZOIC ACID BOC-4-AMINO-3-METHYLBENZOIC ACID 3-AMINO-4-TERT-BUTOXYCARBONYLAMINO-BENZOIC ACID METHYL ESTER DI-BOC-3,4-DIAMINOBENZOIC ACID 4-[(tert-butoxycarbonyl)amino]-2-hydroxybenzoic acid ETHYL 4-(TERT-BUTOXYCARBONYLAMINO)BENZOATE 2,3-DIMETHYL-3,4-DIHYDRO-2H-QUINOXALINE-1,6-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER 4-AMINO-3-(FMOC-AMINOMETHYL)-BENZOIC ACID BUTTPARK 120\07-94

N-ALPHA-T-BUTOXYCARBONYL-4-AMINO-BENZOIC ACID

N-ALPHA-T-BUTOXYCARBONYL-P-AMINOBENZOIC ACID

N-BOC-4-AMINOBENZOIC ACID

Boc-4-aminobenzoic acid98+%

(Tert-Butoxy)Carbonyl 4-Abz-OH

RARECHEM EM WB 0012

N-Boc-4-aminobenzoic

Boc-4-Abz-OH(Boc-4-aMinobenzoic Acid)

Boc-PABA-OH

n-tert-butoxycarbonyl-4-aminobenzoic acid

4-(T-BUTYLOXYCARBONYLAMINO)-BENZOIC ACID

4-(BOC-AMINO)BENZOIC ACID

4-(TERT-BUTYLOXYCARBONYLAMINO)-BENZOIC ACID

4-TERT-BUTOXYCARBONYLAMINO-BENZOIC ACID

BOC-4-AMINOBENZOIC ACID

BOC-4-ABZ-OH

BOC-P-AMINOBENZOIC ACID

BOC-PABA

BOC-P-ABZ-OH

AKOS 90574

N-Boc-4-aminobenzoicacid,97%

4-[(2-methylpropan-2-yl)oxycarbonylamino]benzoic acid

4-(N-tert-Butoxycarbonyl)aMinobenzoic Acid

Boc-4-Abz-OH >=98.0% (T)

N-tert-butoxycarbonyl-para-aminobenzoic acid

4-[[(2-methylpropan-2-yl)oxy-oxomethyl]amino]-1-cyclohexanecarboxylate

4-(tert-Butoxycarbonylamino)benzoic Acid &gt

Benzoic acid, 4-[[(1,1-dimethylethoxy)carbonyl]amino]-

4-[(2-methylpropan-2-yl)oxycarbonylamino]benzoicaci

BOC-4-ABZ-OH USP/EP/BP

66493-39-8

CH33CO2CNHC6H4CO2H

CARBOXYLIC ACID

Peptide Synthesis

Unnatural Amino Acid Derivatives

Specialty Synthesis

Aromatic Amino Acids

Benzene series

Amino Acids