4-METHOXYCINNAMIC ACID
- Product Name
- 4-METHOXYCINNAMIC ACID
- CAS No.
- 943-89-5
- Chemical Name
- 4-METHOXYCINNAMIC ACID
- Synonyms
- PMCA;AKOS B000181;AKOS BB/0034;AKOS BBS-00000769;TIMTEC-BB SBB005717;RARECHEM BK HC T257;OTAVA-BB BB0123400502;4-Methoxycinnamic acid;LABOTEST-BB LT00108121;O-METHYL-P-CUMARIC ACID
- CBNumber
- CB1152939
- Molecular Formula
- C10H10O3
- Formula Weight
- 178.18
- MOL File
- 943-89-5.mol
4-METHOXYCINNAMIC ACID Property
- Melting point:
- 173.5 °C(lit.)
- Boiling point:
- 342.6±17.0 °C(Predicted)
- Density
- 1.195±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- Soluble in ethanol, ethyl acetate and other organic solvents.
- pka
- 4.60±0.10(Predicted)
- form
- powder to crystal
- color
- White to Almost white
- BRN
- 510468
- InChIKey
- AFDXODALSZRGIH-QPJJXVBHSA-N
- LogP
- 1.264 (est)
- CAS DataBase Reference
- 943-89-5(CAS DataBase Reference)
- NIST Chemistry Reference
- 2-Propenoic acid, 3-(4-methoxyphenyl)-, (e)-(943-89-5)
- EPA Substance Registry System
- 2-Propenoic acid, 3-(4-methoxyphenyl)-, (2E)- (943-89-5)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- M0576
- Product name
- trans-4-Methoxycinnamic Acid
- Purity
- >98.0%(GC)(T)
- Packaging
- 25g
- Price
- $31
- Updated
- 2024/03/01
- Product number
- M0576
- Product name
- trans-4-Methoxycinnamic Acid
- Purity
- >98.0%(GC)(T)
- Packaging
- 100g
- Price
- $77
- Updated
- 2024/03/01
- Product number
- A13870
- Product name
- trans-4-Methoxycinnamic acid
- Purity
- 98%
- Packaging
- 10g
- Price
- $21.65
- Updated
- 2024/03/01
- Product number
- A13870
- Product name
- trans-4-Methoxycinnamic acid
- Purity
- 98%
- Packaging
- 50g
- Price
- $80.65
- Updated
- 2024/03/01
- Product number
- A13870
- Product name
- trans-4-Methoxycinnamic acid
- Purity
- 98%
- Packaging
- 250g
- Price
- $336.65
- Updated
- 2024/03/01
4-METHOXYCINNAMIC ACID Chemical Properties,Usage,Production
Uses
Esters derived from trans-4-methoxycinnamic acid are effective absorbers of UV radiation. The starting material was trans-4-methoxycinnamic acid and 3,5dimethoxybenzoic acid methyl ester in isolated avenanthramide alkaloids synthsis. trans-4-Methoxycinnamic acid was converted into its acid chloride (yield 98%) with thionyl chloride. Employed in organic synthesis of pharmaceutical intermediates, synthetic anti-adrenergic drugs esmolol, cosmetics ultraviolet absorption.
Preparation
4-methoxycinnamic acid synthesis : In a 25-mL, roundbottomed flask, 4-methoxybenzaldehyde (0.804 mL, 6.61 mmol) (3), malonic acid (1.75 g, 16.8 mmol), and β-alanine (0.10 g, 1.12 mmol) were dissolved in pyridine (3.0 mL, 37.1 mmol) and heated under reflux for 90 minutes. After cooling to room temperature, the reaction mixture was placed in an ice bath and 8.0 mL of concentrated HCl was slowly added. The resulting white precipitate was collected by vacuum filtration, washed with cold water (2 x 10mL) and dried thoroughly. The product was recrystallized from absolute ethanol (~20 mL).
Synthesis of 4-methoxycinnamic acid
Definition
ChEBI: 4-methoxycinnamic acid is a methoxycinnamic acid having a single methoxy substituent at the 4-position on the phenyl ring. It is functionally related to a cinnamic acid.
Purification Methods
Crystallise the acid from MeOH to constant melting point and UV spectrum. [Beilstein 10 IV 1005.]
4-METHOXYCINNAMIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4-METHOXYCINNAMIC ACID manufacturers
- Product
- 4-METHOXYCINNAMIC ACID 943-89-5
- Price
- US $0.10/KG
- Min. Order
- 1KG
- Purity
- 99.0%
- Supply Ability
- 1000 tons
- Release date
- 2024-08-28
- Product
- (E)-4-Methoxycinnamic Acid 943-89-5
- Price
- US $1.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 50 tons
- Release date
- 2020-01-20
- Product
- 4-methoxycinnamicacid 943-89-5
- Price
- US $25.00/KG
- Min. Order
- 1KG
- Purity
- 0.99
- Supply Ability
- 20 tons
- Release date
- 2021-12-31