ChemicalBook > CAS DataBase List > 4-Methoxycinnamic acid

4-Methoxycinnamic acid

Product Name
4-Methoxycinnamic acid
CAS No.
830-09-1
Chemical Name
4-Methoxycinnamic acid
Synonyms
P-METHOXYCINNAMIC ACID;(E)-3-(4-METHOXYPHENYL)ACRYLIC ACID;4-methoxycinnamate;(E)-Methyl 3-(4-hydroxyphenyl)acrylate;TRANS-4-METHOXYCINNAMIC ACID;PMCA;AKOS BB/0034;AKOS B000181;AKOS BBS-00000769;RARECHEM BK HC T257
CBNumber
CB8152938
Molecular Formula
C10H10O3
Formula Weight
178.18
MOL File
830-09-1.mol
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4-Methoxycinnamic acid Property

Melting point:
173.5 °C(lit.)
Boiling point:
250.41°C (rough estimate)
Density 
1.1479 (rough estimate)
refractive index 
1.5088 (estimate)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
Soluble in dimethyl sulfoxide and methanol.
pka
pK1:4.539 (25°C)
form 
Fine Crystalline Powder
color 
White
LogP
2.680
CAS DataBase Reference
830-09-1(CAS DataBase Reference)
NIST Chemistry Reference
2-Propenoic acid, 3-(4-methoxyphenyl)-(830-09-1)
EPA Substance Registry System
2-Propenoic acid, 3-(4-methoxyphenyl)- (830-09-1)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-37/39-36
WGK Germany 
3
RTECS 
UD3391300
8
Hazard Note 
Irritant
TSCA 
Yes
HS Code 
29173990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
M13807
Product name
4-Methoxycinnamic acid, predominantly trans
Purity
99%
Packaging
5g
Price
$33.5
Updated
2023/06/20
Sigma-Aldrich
Product number
M13807
Product name
4-Methoxycinnamic acid, predominantly trans
Purity
99%
Packaging
25g
Price
$77.9
Updated
2023/06/20
Alfa Aesar
Product number
H60144
Product name
4-Methoxycinnamic acid, 99%
Packaging
25g
Price
$53.65
Updated
2024/03/01
Alfa Aesar
Product number
H60144
Product name
4-Methoxycinnamic acid, 99%
Packaging
100g
Price
$146.65
Updated
2024/03/01
Sigma-Aldrich
Product number
M13807
Product name
4-Methoxycinnamic acid, predominantly trans
Purity
99%
Packaging
100g
Price
$201
Updated
2024/03/01
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4-Methoxycinnamic acid Chemical Properties,Usage,Production

Chemical Properties

white fine crystalline powde

Uses

It exerts anti-hyperglycemic/ hypoglycemic effect by stimulating insulin secretion from pancreas. It could be developed into a new potential therapeutic agent used in type 2 diabetic patients.

Uses

4-Methoxycinnamic acid(p-MCA) exerted antihyperglycemic/hypoglycemic effect by stimulating insulin secretion from pancreas and could be developed into a new potential for therapeutic agent used in type 2 diabetic patients.

Definition

ChEBI: A methoxycinnamic acid having a single methoxy substituent at the 4-position on the phenyl ring.

Synthesis Reference(s)

Journal of the American Chemical Society, 79, p. 3452, 1957 DOI: 10.1021/ja01570a037
Tetrahedron Letters, 31, p. 5913, 1990 DOI: 10.1016/S0040-4039(00)97992-9

Purification Methods

Crystallise the acid from MeOH to constant melting point and UV spectrum. [Beilstein 10 IV 1005.]

4-Methoxycinnamic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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4-Methoxycinnamic acid Suppliers

Zaoyang Cixiang Medical Technology Co., Ltd
Tel
19871689299
Email
1242417277@qq.com
Country
China
ProdList
52
Advantage
58
Wuhan lenmaike Industrial Co., Ltd.
Tel
027-83916065 18108665271
Fax
027-83916065
Email
landmarkorganic@qq.com
Country
China
ProdList
68
Advantage
58
Zaoyang cixiang medical technology co. LTD
Tel
0523-15971080675 15971080675
Email
385091169@qq.com
Country
China
ProdList
44
Advantage
58
Wuhan Vanzpharm Inc.
Tel
027-84492310 13657243668
Fax
027-84492310
Email
wangting@vanzpharm.com
Country
China
ProdList
53
Advantage
58
Suzhou dexuan New Material Technology Co., Ltd
Tel
13773006286
Email
siyzhxl@163.com
Country
China
ProdList
27
Advantage
58
Zhengzhou HongSheng Pharmaceutical Co., Ltd.
Tel
1352-6885213 15637198702
Fax
0371-63709726
Email
xpkchem@163.com
Country
China
ProdList
3998
Advantage
58
Jinan Dexinjia Bio&Tech Co., Ltd
Tel
0531-8237592 15562613975
Fax
0531-82375893
Email
3416953599@qq.com
Country
China
ProdList
1172
Advantage
58
Zaoyang Cixiang Pharmaceutical Technology Co., LTD
Tel
15671321689
Email
carrie@cixiangyy.com
Country
China
ProdList
19
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
MedicalChem(Yancheng)Manuf.Co.,Ltd
Tel
+86-515-84383180
Fax
+86-515-84383182
Email
sales@medicalchem.com
Country
China
ProdList
80
Advantage
69
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View Lastest Price from 4-Methoxycinnamic acid manufacturers

Hebei Yime New Material Technology Co., Ltd.
Product
4-Methoxycinnamic acid 830-09-1
Price
US $100.00-90.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20t
Release date
2022-10-12
Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
4-Methoxycinnamic Acid 830-09-1
Price
US $120.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20ton
Release date
2024-04-24
Henan Fengda Chemical Co., Ltd
Product
4-Methoxycinnamic acid 830-09-1
Price
US $8.00-3.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-04-03

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