4-Hydroxycinnamic acid
- Product Name
- 4-Hydroxycinnamic acid
- CAS No.
- 7400-08-0
- Chemical Name
- 4-Hydroxycinnamic acid
- Synonyms
- 4-Hydroxycinnamic acid;P-HYDROXYCINNAMIC ACID;TRANS-4-COUMARIC ACID;TRANS-P-COUMARIC ACID;PHCA;P-CUMARIC ACID;TRANS-P-CUMARIC ACID;4-hydroxylcinnamic acid;3-(4-HYDROXYPHENYL)ACRYLIC ACID;3-(4-Hydroxyphenyl)propenoic acid
- CBNumber
- CB9164396
- Molecular Formula
- C9H8O3
- Formula Weight
- 164.16
- MOL File
- 7400-08-0.mol
4-Hydroxycinnamic acid Property
- Melting point:
- 214 °C (dec.)(lit.)
- Boiling point:
- 251.61°C (rough estimate)
- Density
- 1.2132 (rough estimate)
- refractive index
- 1.5380 (estimate)
- storage temp.
- Store below +30°C.
- solubility
- Acetone (Slightly), Chloroform (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- 4.65±0.10(Predicted)
- color
- White to Off-White
- biological source
- rabbit
- Stability:
- Light Sensitive
- Cosmetics Ingredients Functions
- SKIN CONDITIONING
- InChI
- InChI=1S/C9H8O3/c10-8-4-1-7(2-5-8)3-6-9(11)12/h1-6,10H,(H,11,12)
- InChIKey
- NGSWKAQJJWESNS-UHFFFAOYSA-N
- SMILES
- C(O)(=O)C=CC1=CC=C(O)C=C1
- LogP
- 1.790
- CAS DataBase Reference
- 7400-08-0(CAS DataBase Reference)
- NIST Chemistry Reference
- 2-Propenoic acid, 3-(4-hydroxyphenyl)-(7400-08-0)
- EPA Substance Registry System
- p-Hydroxycinnamic acid (7400-08-0)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36-36/37/39-22
- WGK Germany
- 2
- RTECS
- GD9095000
- TSCA
- TSCA listed
- HS Code
- 2918 29 00
- Storage Class
- 11 - Combustible Solids
- Hazard Classifications
- Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 8.00237
- Product name
- 4-Hydroxycinnamic acid
- Purity
- for synthesis
- Packaging
- 10g
- Price
- $58.4
- Updated
- 2025/07/31
- Product number
- SAB1303797
- Product name
- ANTI-ACER3 (C-TERM) antibody produced in rabbit
- Purity
- IgG fraction of antiserum, buffered aqueous solution
- Packaging
- 400μL
- Price
- $496
- Updated
- 2025/07/31
- Product number
- 8.00237
- Product name
- 4-Hydroxycinnamic acid
- Purity
- for synthesis
- Packaging
- 50g
- Price
- $148
- Updated
- 2025/07/31
- Product number
- SAB4502315
- Product name
- Anti-PHCA antibody produced in rabbit
- Purity
- affinity isolated antibody
- Packaging
- 100μG
- Price
- $434
- Updated
- 2022/05/15
- Product number
- C755365
- Product name
- p-Coumaric acid
- Packaging
- 250g
- Price
- $275
- Updated
- 2021/12/16
4-Hydroxycinnamic acid Chemical Properties,Usage,Production
Chemical Properties
Light yellow to beige crystalline powder with aroma, soluble in methanol, ethanol, DMSO and other organic solvents, derived from synthesis.
Uses
4-Hydroxycinnamic acid is the hydroxy derivative of Cinnamic Acid with antioxidant properties. It is a is a major component of lignocellulose. Studies suggest that 4-Hydroxycinnamic acid may reduce the risk of cancer by reducing the formation of carcinogenic nitrosamines. A recent study reports that 4-Hydroxycinnamic acid may act as a chemical castrator in bees by altering the epression of genes required for ovary development. This compound is common in pollen a major constituent of the worker bee diet, but it is not found in queen bees'royal jelly.
Application
p-Hydroxycinnamic acid is mainly used as an intermediate in the pharmaceutical and perfume industries. It can react with dimethyl sulfate to produce p-anisaldehyde, react with acetaldehyde to produce p-hydroxycinnamaldehyde, and further oxidize it to produce cinnamic acid. This product can be directly oxidized to produce 4-Hydroxybenzoic acid and reduction to produce 4-Hydroxybenzyl alcohol.
Definition
ChEBI: 4-coumaric acid is a coumaric acid in which the hydroxy substituent is located at C-4 of the phenyl ring. It has a role as a plant metabolite. It is a conjugate acid of a 4-coumarate.
Hazard
Moderately toxic.
Safety Profile
Moderarely toxic by intraperitoneal route. Experimental reproductive effects. When heated to decomposition it emits acrid smoke and fumes. See also COUMARIN
4-Hydroxycinnamic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4-Hydroxycinnamic acid manufacturers
- Product
- 4-Hydroxycinnamic acid 7400-08-0
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 1000kg
- Release date
- 2025-07-18
- Product
- p-Hydroxy-cinnamic acid 7400-08-0
- Price
- US $10.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-11-28
- Product
- 4-Hydroxycinnamic acid 7400-08-0
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-10-17