ChemicalBook > CAS DataBase List > 4-Methoxycinnamic acid

4-Methoxycinnamic acid

Product Name
4-Methoxycinnamic acid
CAS No.
830-09-1
Chemical Name
4-Methoxycinnamic acid
Synonyms
P-METHOXYCINNAMIC ACID;(E)-3-(4-METHOXYPHENYL)ACRYLIC ACID;4-methoxycinnamate;(E)-Methyl 3-(4-hydroxyphenyl)acrylate;TRANS-4-METHOXYCINNAMIC ACID;PMCA;AKOS BB/0034;AKOS B000181;AKOS BBS-00000769;RARECHEM BK HC T257
CBNumber
CB8152938
Molecular Formula
C10H10O3
Formula Weight
178.18
MOL File
830-09-1.mol
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4-Methoxycinnamic acid Property

Melting point:
173.5 °C(lit.)
Boiling point:
250.41°C (rough estimate)
Density 
1.1479 (rough estimate)
refractive index 
1.5088 (estimate)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
Soluble in dimethyl sulfoxide and methanol.
pka
pK1:4.539 (25°C)
form 
Fine Crystalline Powder
color 
White
InChI
InChI=1S/C10H10O3/c1-13-9-5-2-8(3-6-9)4-7-10(11)12/h2-7H,1H3,(H,11,12)
InChIKey
AFDXODALSZRGIH-UHFFFAOYSA-N
SMILES
C(O)(=O)C=CC1=CC=C(OC)C=C1
LogP
2.680
CAS DataBase Reference
830-09-1(CAS DataBase Reference)
NIST Chemistry Reference
2-Propenoic acid, 3-(4-methoxyphenyl)-(830-09-1)
EPA Substance Registry System
2-Propenoic acid, 3-(4-methoxyphenyl)- (830-09-1)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-37/39-36
WGK Germany 
3
RTECS 
UD3391300
F 
8
Hazard Note 
Irritant
TSCA 
Yes
HS Code 
29173990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
M13807
Product name
4-Methoxycinnamic acid, predominantly trans
Purity
99%
Packaging
5g
Price
$33.5
Updated
2023/06/20
Sigma-Aldrich
Product number
M13807
Product name
4-Methoxycinnamic acid, predominantly trans
Purity
99%
Packaging
25g
Price
$77.9
Updated
2023/06/20
Alfa Aesar
Product number
H60144
Product name
4-Methoxycinnamic acid, 99%
Packaging
25g
Price
$53.65
Updated
2024/03/01
Alfa Aesar
Product number
H60144
Product name
4-Methoxycinnamic acid, 99%
Packaging
100g
Price
$146.65
Updated
2024/03/01
Sigma-Aldrich
Product number
M13807
Product name
4-Methoxycinnamic acid, predominantly trans
Purity
99%
Packaging
100g
Price
$201
Updated
2024/03/01
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4-Methoxycinnamic acid Chemical Properties,Usage,Production

Chemical Properties

white fine crystalline powde

Uses

It exerts anti-hyperglycemic/ hypoglycemic effect by stimulating insulin secretion from pancreas. It could be developed into a new potential therapeutic agent used in type 2 diabetic patients.

Uses

4-Methoxycinnamic acid(p-MCA) exerted antihyperglycemic/hypoglycemic effect by stimulating insulin secretion from pancreas and could be developed into a new potential for therapeutic agent used in type 2 diabetic patients.

Definition

ChEBI: A methoxycinnamic acid having a single methoxy substituent at the 4-position on the phenyl ring.

Synthesis Reference(s)

Journal of the American Chemical Society, 79, p. 3452, 1957 DOI: 10.1021/ja01570a037
Tetrahedron Letters, 31, p. 5913, 1990 DOI: 10.1016/S0040-4039(00)97992-9

Purification Methods

Crystallise the acid from MeOH to constant melting point and UV spectrum. [Beilstein 10 IV 1005.]

4-Methoxycinnamic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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4-Methoxycinnamic acid Suppliers

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View Lastest Price from 4-Methoxycinnamic acid manufacturers

Hebei Andu Technology Com.,Ltd
Product
4-Methoxycinnamic acid 830-09-1
Price
US $3.50/kg
Min. Order
1kg
Purity
≥99%
Supply Ability
3000tons/month
Release date
2024-08-25
Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
4-Methoxycinnamic Acid 830-09-1
Price
US $120.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20ton
Release date
2024-04-24
Hebei Weibang Biotechnology Co., Ltd
Product
4-Methoxycinnamic acid 830-09-1
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-11-28

830-09-1, 4-Methoxycinnamic acidRelated Search:

Ethyl cinnamate trans-Cinnamic acid 4-Hydroxycinnamic acid Stearic acid Folic acid Glycine Citric acid Ethyl 2-(Chlorosulfonyl)acetate Cinnamic acid 4-Methylcinnamic acid alpha-Methylcinnamic acid METHYL 4-METHYLCINNAMATE Methyl cinnamate 4-(Methylthio)benzaldehyde Anisonitrile Ascoric Acid p-Methoxycinnamic acid 2-ethylhexyl ester,p-Methoxycinnamic acid 2-ethylhexyl ester Octyl 4-methoxycinnamate

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