BOC-CYS-OH

Product Name: BOC-CYS-OH
CAS No.: 20887-95-0
Chemical Name: BOC-CYS-OH
Synonyms: BOC-CYS-OH;BOC-L-CYS-OH;BOC-L-CYSTEINE;N-Boc-L-cysteine;Boc-Cys-Cysteine;BOC-CYS-OH USP/EP/BP;N-ALPHA-T-BOC-L-CYSTEINE;Boc-Cys-OH,Boc-L-cysteine;Boc-L-cysteine≥ 98% (HPLC);Boc-Cys-OH (cryst) Novabiochem
CBNumber: CB1153365
Molecular Formula: C8H15NO4S
Formula Weight: 221.27
MOL File: 20887-95-0.mol

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BOC-CYS-OH Property

Melting point:: 67-70°C
Boiling point:: 361.4±37.0 °C(Predicted)
Density: 1?+-.0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Sealed in dry,2-8°C
solubility: DMSO (Slightly), Ethanol (Slightly, Sonicated), Methanol
form: Solid
pka: 3.57±0.10(Predicted)
color: White to Off-White
optical activity: [α]20/D +8.0±1.5°, c = 1% in ethanol
BRN: 2450705
InChI: InChI=1S/C8H15NO4S/c1-8(2,3)13-7(12)9-5(4-14)6(10)11/h5,14H,4H2,1-3H3,(H,9,12)(H,10,11)/t5-/m0/s1
InChIKey: ATVFTGTXIUDKIZ-YFKPBYRVSA-N
SMILES: C(O)(=O)[C@H](CS)NC(OC(C)(C)C)=O
CAS DataBase Reference: 20887-95-0(CAS DataBase Reference)

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Safety

Safety Statements: 24/25
WGK Germany: 3
HS Code: 29309090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H372Causes damage to organs through prolonged or repeated exposure

H413May cause long lasting harmful effects to aquatic life

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 8.53031
Product name: Boc-Cys-OH (cryst)
Purity: Novabiochem?
Packaging: 5G
Price: $266
Updated: 2025/07/31

Sigma-Aldrich

Product number: 8.53031
Product name: Boc-Cys-OH (cryst)
Purity: Novabiochem?
Packaging: 25G
Price: $982
Updated: 2023/06/20

Sigma-Aldrich

Product number: 15411
Product name: Boc-Cys-OH
Purity: for chiral derivatization, ≥98.5%
Packaging: 250mg
Price: $84
Updated: 2022/05/15

Sigma-Aldrich

Product number: 15411
Product name: Boc-Cys-OH
Purity: for chiral derivatization, ≥98.5%
Packaging: 1g
Price: $314
Updated: 2022/05/15

Usbiological

Product number: 264624
Product name: Boc-L-cysteine
Packaging: 1g
Price: $319
Updated: 2021/12/16

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BOC-CYS-OH Chemical Properties,Usage,Production

Chemical Properties

light yellowliquid

Uses

Boc-L-cysteine is the protected form of L-Cysteine (C995000), a non-essential α-amino acid that is biosynthesized in humans. L-Cysteine is also a bicarbonate-sensitive endogenous excitotoxin in rats and possibly humans.

reaction suitability

reaction type: Boc solid-phase peptide synthesis

Synthesis

10389-65-8

20887-95-0

General procedure for the synthesis of (R)-2-((tert-butoxycarbonyl)amino)-3-mercaptopropionic acid from N,N'-bis(Boc)-L-cystine: N,N'-bis(Boc)-L-cystine (2.51 mmol) was dissolved in a solvent mixture of tetrahydrofuran (29.2 mL) and water (0.8 mL). Tributylphosphine (2.76 mmol) was added to the solution under ice bath cooling conditions. The reaction mixture was gradually warmed up to room temperature and stirred continuously at this temperature for 1 hour. Upon completion of the reaction, ethyl acetate (20 mL) and 10% aqueous citric acid (10 mL) were added to the reaction mixture for extraction and separation. The organic phase was collected and washed with saturated aqueous saline solution (20 mL). Subsequently, the organic phase was concentrated and the resulting residue was purified by silica gel column chromatography (eluent: hexane-ethyl acetate mixed solvent) to afford the target compound 22 as an oily product. Yield: 99%. ESI MS m/z 220.1 [M-H]-; 1H NMR (400 MHz, CDCl3) δ: 5.47 (1H, brs), 4.65 (1H, brs), 3.09-2.97 (2H, m), 1.48 (9H, s).

References

[1] Patent: US2012/282386, 2012, A1. Location in patent: Page/Page column 15
[2] Journal of Nanoparticle Research, 2017, vol. 19, # 6,
[3] Angewandte Chemie, 1993, vol. 105, # 2, p. 311 - 313
[4] Chemische Berichte, 1969, vol. 102, p. 1048 - 1052
[5] Protein and Peptide Letters, 2014, vol. 21, # 12, p. 1257 - 1264

BOC-CYS-OH Preparation Products And Raw materials

Raw materials

Preparation Products

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BOC-CYS-OH Suppliers

China 144 Germany 5 India 3 Japan 3 South Korea 1 Switzerland 2 United Kingdom 4 United States 24 Global 186

SINO High Goal Chemical Technology Co., Ltd.

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Capot Chemical Co., Ltd

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Accela ChemBio Co.,Ltd.

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Syntechem Co.,Ltd

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Sinopharm Chemical Reagent Co,Ltd.

Tel: 86-21-63210123
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Shanghai Sunway Pharmaceutical Technology Co., Ltd

Tel: 18270980682
Fax: 021 51613951
Email: mlcheng@sunwaypharm.cn
Country: China
ProdList: 8669
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View Lastest Price from BOC-CYS-OH manufacturers

Hebei Chuanghai Biotechnology Co,.LTD

Product: BOC-CYS-OH 20887-95-0
Price: US $2.60/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 5000kg
Release date: 2024-08-09

Zhuozhou Wenxi import and Export Co., Ltd

Product: BOC-CYS-OH 20887-95-0
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-08-11

Career Henan Chemical Co

Product: BOC-CYS-OH 20887-95-0
Price: US $7.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100KG
Release date: 2019-08-31

20887-95-0, BOC-CYS-OHRelated Search:

BOC-CYS(ET)-OH BOC-CYS-OH BOC-CYS(4-MEOBZL)-OH BOC-S-TERT-BUTYLMERCAPTO-L-CYSTEINE BOC-CYS(ME)-OH BOC-L-THIAZOLIDINE-4-CARBOXYLIC ACID BOC-CYS(ACM)-OH BOC-PEN(MOB)-OH Boc-S-Benzyl-L-cysteine Boc-S-(4-methylbenzyl)-L-cysteine (Boc-Cys-OH)2 (Disulfide bond),(BOC-CYS-OH)2 N-Boc-S-Trityl-L-cysteine BOC-CYS(DPM)-OH BOC-CYS(TBU)-OH BOC-CYS(FM)-OH BOC-S-(4-METHOXYBENZYL)-L-CYSTEINE DICYCLOHEXYLAMINE SALT BOC-CYS(BZL)-ONP BOC-CYS(3,4-DIMETHYLBENZYL)-OH

N-[(tert-Butyloxy)carbonyl]-L-cysteine

(S)-2-tert-Butoxycarbonylamino-3-mercapto-propionic acid

(2R)-2-(tert-butoxycarbonylamino)-3-mercapto-propionic acid

(2R)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-sulfanylpropanoic acid

(2R)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-sulfanyl-propanoic acid

Boc-Cys-OH,Boc-L-cysteine

(2R)-2-[(tert-butoxycarbonyl)aMino]-3-sulfanylpropanoic acid

N-Boc-L-cysteine

(R)-2-((tert-butoxycarbonyl)aMino)-3-Mercaptopropanoic acid

Boc-L-cysteine, for chiral derivatization

Boc-L-cysteine≥ 98% (HPLC)

Boc-Cys-OH (cryst) Novabiochem

N-ALPHA-T-BUTOXYCARBONYL-L-CYSTEINE

N-ALPHA-T-BUTYLOXYCARBONYL-L-CYSTEINE

N-ALPHA-TERT-BUTYLOXYCARBONYL-L-CYSTEINE

N-ALPHA-T-BOC-L-CYSTEINE

BOC-CYS-OH

BOC-L-CYSTEINE

BOC-L-CYS-OH

N-(tert-Butoxycarbonyl)-L-cysteine

N-tert-butyloxycarbonylcysteine

N-(tert-Butyloxycarbonyl)-L-cysteine

Boc-L-cysteine, 98%, for chiral derivatization

L-Cysteine, N-[(1,1-dimethylethoxy)carbonyl]-

(2R)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-sulfanylpropanoicaci

BOC-CYS-OH USP/EP/BP

Boc-Cys-Cysteine

(2R)-2-(tert-butoxycarbonylamino)-3-sulfanyl-propanoic acid - [B84635]

20887-95-0

Cysteine/Cystine

Specialty Synthesis

Peptide Synthesis

Amino Acid Derivatives

Boc-Amino acid series

Amino Acids

Pharmaceutical Intermediates