alpha-Methylcinnamic acid
- Product Name
- alpha-Methylcinnamic acid
- CAS No.
- 1199-77-5
- Chemical Name
- alpha-Methylcinnamic acid
- Synonyms
- (E)-2-Methyl-3-phenylacrylic acid;A-METHYLCINNAMIC ACID;2-Methyl-3-phenylacrylic acid;2M3B;α-MethyL;α-Methylciamic acid;RARECHEM AL BM 0531;α-Methylcinmic acid;alpha-Methylcinnamic;α-Methylcinnamicacid
- CBNumber
- CB1176094
- Molecular Formula
- C10H10O2
- Formula Weight
- 162.19
- MOL File
- 1199-77-5.mol
alpha-Methylcinnamic acid Property
- Melting point:
- 79-81 °C(lit.)
- Boiling point:
- 288 °C
- Density
- 1.0281 (rough estimate)
- refractive index
- 1.6000 (estimate)
- storage temp.
- Sealed in dry,Room Temperature
- form
- Crystals or Crystalline Powder
- pka
- 4.82±0.10(Predicted)
- color
- White to yellow
- BRN
- 2042544
- InChI
- InChI=1S/C10H10O2/c1-8(10(11)12)7-9-5-3-2-4-6-9/h2-7H,1H3,(H,11,12)
- InChIKey
- XNCRUNXWPDJHGV-BQYQJAHWSA-N
- SMILES
- C(O)(=O)C(C)=CC1=CC=CC=C1
- LogP
- 2.600
- CAS DataBase Reference
- 1199-77-5(CAS DataBase Reference)
- NIST Chemistry Reference
- «ALPHA»-methylcinnamic acid(1199-77-5)
Safety
- Safety Statements
- 22-24/25
- WGK Germany
- 3
- HS Code
- 29163900
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- M35606
- Product name
- α-Methylcinnamic acid
- Purity
- 99%
- Packaging
- 25g
- Price
- $155
- Updated
- 2025/07/31
- Product number
- M35606
- Product name
- α-Methylcinnamic acid
- Purity
- 99%
- Packaging
- 100g
- Price
- $305
- Updated
- 2023/01/07
- Product number
- M1336
- Product name
- α-Methylcinnamic Acid
- Purity
- >98.0%(GC)(T)
- Packaging
- 5g
- Price
- $29
- Updated
- 2025/07/31
- Product number
- M1336
- Product name
- α-Methylcinnamic Acid
- Purity
- >98.0%(GC)(T)
- Packaging
- 25g
- Price
- $78
- Updated
- 2025/07/31
- Product number
- B495030
- Product name
- α-Methylcinnamic acid
- Packaging
- 1g
- Price
- $55
- Updated
- 2021/12/16
alpha-Methylcinnamic acid Chemical Properties,Usage,Production
Chemical Properties
WHITE TO YELLOWISH CRYSTALS OR CRYSTALLINE POWDER
Uses
Alpha-methylcinnamic acid
Synthesis Reference(s)
Journal of the American Chemical Society, 94, p. 2520, 1972 DOI: 10.1021/ja00762a060
Synthetic Communications, 19, p. 71, 1989 DOI: 10.1080/00397918908050954
Synthesis
100-52-7
123-62-6
1199-77-5
General procedure: Propionic anhydride (300 mmol, 1.6 eq.) was slowly added to a reaction vial containing potassium carbonate (224 mmol, 1.2 eq.) at 0 °C. After stirring for 5 min, benzaldehyde (186 mmol, 1.0 eq.) was added dropwise to the mixture. The reaction mixture was heated to reflux and maintained for 12 hours. Upon completion of the reaction, the mixture was cooled to room temperature using an ice bath, followed by addition of water (appropriate amount) and solid Na2CO3 (30 g) to the reaction mixture. The resulting yellow precipitate was collected by filtration and the filtrate was acidified to pH 6.0 with concentrated HCl to precipitate a solid product of 2-methyl-3-phenylpropenoic acid.
References
[1] Medicinal Chemistry Research, 2004, vol. 13, # 8-9, p. 660 - 676
[2] European Journal of Medicinal Chemistry, 2013, vol. 62, p. 632 - 648
[3] American Chemical Journal, 1906, vol. 36, p. 533
[4] Journal of the Chemical Society, 1877, vol. 31, p. 409
[5] Journal of the Chemical Society, 1878, vol. 33, p. 215
alpha-Methylcinnamic acid Preparation Products And Raw materials
Raw materials
Preparation Products
alpha-Methylcinnamic acid Suppliers
View Lastest Price from alpha-Methylcinnamic acid manufacturers
- Product
- Alpha-Methylcinnamic acid 1199-77-5
- Price
- US $0.00/G
- Min. Order
- 50G
- Purity
- 98%min
- Supply Ability
- 30kg/month
- Release date
- 2023-02-02
- Product
- alpha-Methylcinnamic acid 1199-77-5
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-11-15
- Product
- alpha-Methylcinnamic acid 1199-77-5
- Price
- US $10.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 20 ton
- Release date
- 2024-11-20