ALPHA-CYANO-4-HYDROXYCINNAMIC ACID

Product Name: ALPHA-CYANO-4-HYDROXYCINNAMIC ACID
CAS No.: 28166-41-8
Chemical Name: ALPHA-CYANO-4-HYDROXYCINNAMIC ACID
Synonyms: α-Cyano-4-hydroxycinnamic Acid;ACCA;α-CHCA;A-CYANO-4-HYDROXYCINNAMIC ACID;α-CCA;4-HCCA;α-CHCA;α-Cyano;ALPHA-CCA;ALPHA-CHCA
CBNumber: CB0781327
Molecular Formula: C10H7NO3
Formula Weight: 189.17
MOL File: 28166-41-8.mol

More

Less

ALPHA-CYANO-4-HYDROXYCINNAMIC ACID Property

Melting point:: 245-250 °C(lit.)
Boiling point:: 324.41°C (rough estimate)
Density: 1.3175 (rough estimate)
refractive index: 1.5400 (estimate)
storage temp.: 2-8°C
solubility: methanol: 10 mg/mL, clear
form: powder
pka: 0.85±0.10(Predicted)
color: yellow
BRN: 3271427
InChIKey: AFVLVVWMAFSXCK-VMPITWQZSA-N
CAS DataBase Reference: 28166-41-8(CAS DataBase Reference)

More

Less

Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3
F: 10-23
HS Code: 29269090

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H317May cause an allergic skin reaction

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 70990
Product name: α-Cyano-4-hydroxycinnamic acid
Purity: matrixsubstanceforMALDI-MS,≥99.0%(HPLC)
Packaging: 250mg
Price: $42.8
Updated: 2024/03/01

Sigma-Aldrich

Product number: 70990
Product name: α-Cyano-4-hydroxycinnamic acid
Purity: matrixsubstanceforMALDI-MS,≥99.0%(HPLC)
Packaging: 1g
Price: $118
Updated: 2024/03/01

Sigma-Aldrich

Product number: 145505
Product name: α-Cyano-4-hydroxycinnamic acid
Purity: 97%
Packaging: 5g
Price: $73.9
Updated: 2024/03/01

Sigma-Aldrich

Product number: 39468
Product name: α-Cyano-4-hydroxycinnamic acid
Purity: matrixsubstanceforMALDI-MS,Ultrapure
Packaging: 10x10mg
Price: $332
Updated: 2024/03/01

Sigma-Aldrich

Product number: 145505
Product name: α-Cyano-4-hydroxycinnamic acid
Purity: 97%
Packaging: 25g
Price: $97.2
Updated: 2024/03/01

More

Less

ALPHA-CYANO-4-HYDROXYCINNAMIC ACID Chemical Properties,Usage,Production

Chemical Properties

yellow crystalline powder

Uses

inhibitor of mitochondrial pyruvate transport

Uses

α-Cyano-4-hydroxycinnamic acid (CHC) was used in encapsulation of CHC into NaY zeolite. It was used as matrix to investigate the activity of the paclitaxel derivatives using several well-established in vitro angiogenesis assays.

Uses

α-Cyano-4-hydroxycinnamic acid(CHC) was used as a matrix for peptides and nucleotides in mass spectroscopic analysis. It was used in encapsulation of CHC into NaY zeolite. It was used as matrix to investigate the activity of the paclitaxel derivatives using several well-established in vitro angiogenesis assays.

Definition

ChEBI: Alpha-cyano-4-hydroxycinnamic acid is a monohydroxycinnamic acid that is 4-hydroxycinnamic acid in which the hydrogen alpha- to the carboxy group is replaced by a cyano group. It is used as a matrix in matrix-assisted laser desorption/ionization (MALDI) mass spectrometry for the analysis of peptides and oligonucleotides. It has a role as a MALDI matrix material. It is a nitrile, a member of phenols and a monohydroxycinnamic acid.

General Description

α-Cyano-4-hydroxycinnamic acid is the commonly used matrix for analyzing peptides by matrix-assisted laser desorption/ionization mass spectrometry. It inhibits the monophenolase activity and diphenolase activity of mushroom tyrosinase.

Biochem/physiol Actions

α-Cyano-4-hydroxycinnamic acid acts as a specific inhibitor of monocarboxylic acid transport, including lactate and pyruvate transport. It is also reported to block β-cell apical anion exchange (IC50 of 2.4 mM).

storage

Store at +4°C

ALPHA-CYANO-4-HYDROXYCINNAMIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

ALPHA-CYANO-4-HYDROXYCINNAMIC ACID Suppliers

Americas 1 Belgium 1 China 110 Europe 2 Germany 3 India 5 Japan 4 Slovakia 1 Switzerland 1 United Kingdom 6 United States 25 USA 1 Global 160

Zhangjiagang Xikai Chemical Co.,Ltd

Tel: +86-0512-55701600 +86-13962289590
Fax: 0512-58538687
Email: sales@xikaichem.com
Country: China
ProdList: 271
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 94657
Advantage: 76

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 021-61259108 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40228
Advantage: 62

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24529
Advantage: 81

Beijing HwrkChemical Technology Co., Ltd

Tel: 010-89508211 18501085097
Fax: 010-89508210
Email: sales.bj@hwrkchemical.com
Country: China
ProdList: 8418
Advantage: 55

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44688
Advantage: 61

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42958
Advantage: 64

Syntechem Co.,Ltd

Tel
Fax: E-Mail Inquiry
Email: info@syntechem.com
Country: China
ProdList: 12984
Advantage: 57

Maya High Purity Chemicals

Tel: +86 (573) 82222445 (0)18006601000 452520369
Fax: +86 (573) 82222643
Email: sales@maya-r.com
Country: China
ProdList: 11707
Advantage: 57

Spectrum Chemical Manufacturing Corp.

Tel: 021-021-021-67601398-809-809-809 15221380277
Fax: 021-57711696
Email: marketing_china@spectrumchemical.com
Country: China
ProdList: 9658
Advantage: 60

More

Less

View Lastest Price from ALPHA-CYANO-4-HYDROXYCINNAMIC ACID manufacturers

Shanghai Qyubiotech Co., Ltd.

Product: a-Cyano-4-hydroxycinnamic acid 28166-41-8
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%+
Supply Ability: 100000kg per Month
Release date: 2023-08-25

Henan Fengda Chemical Co., Ltd

Product: ALPHA-CYANO-4-HYDROXYCINNAMIC ACID 28166-41-8
Price: US $10.00-2.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2024-04-28

Zhuozhou Wenxi import and Export Co., Ltd

Product: ALPHA-CYANO-4-HYDROXYCINNAMIC ACID 28166-41-8
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-08-11

28166-41-8, ALPHA-CYANO-4-HYDROXYCINNAMIC ACIDRelated Search:

ALPHA-CYANO-4-HYDROXYCINNAMIC ACID CDC ALPHA-CYANO-4-METHOXYCINNAMIC ACID 1-BENZYL-4-CYANO-4-HYDROXYPIPERIDINE 4'-Hydroxy-4-biphenylcarbonitrile N-Butyl-3-cyano-6-hydroxy-4-methyl-2-pyridone 2-CYANO-6-HYDROXYBENZOTHIAZOLE 1-BENZYL-4-CYANO-4-HYDROXYPIPERIDINE HYDROCHLORIDE 98 Ethyl (R)-(-)-4-cyano-3-hydroxybutyate Ethyl (S)-4-cyano-3-hydroxybutyrate 3-Cyano-6-methyl-2(1H)-pyridinone 2-CYANO-3-HYDROXYPYRIDINE 3-Cyano-4-hydroxybenzoic acid 1-Ethyl-6-hydroxy-4-methyl-2-oxo-1,2-dihydropyridine-3-carbonitrile 3-Cyano-2-hydroxypyridine 1,2-DIHYDRO-4-(METHOXYMETHYL)-6-METHYL-5-NITRO-2-OXONICOTINONITRILE 2-Cyano-5-hydroxypyridine 5-Hydroxy-2-pyrimidinecarbonitrile

4-HCCA

A-CYANO-4-HYDROXYCINNAMIC ACID

ACCA

ALPHA-CCA

ALPHA-CHCA

ALPHA-CYANO

ALPHA-CYANO-4-HYDROXYCINNAMIC ACID

LABOTEST-BB LT00159295

ALPHA-CYANO-4-HYDROXYCINNAMIC ACID, USE

ALPHA-CYANO-4-HYDROXYCINNAMIC ACID PGE.WITH 10 X 25 MG

alpha-cyano-4-hydroxycinnamate

2-CYANO-3-(4-HYDROXYPHENYL)ACRYLIC ACID

α-CCA, α-CHCA, α-Cyano, 4-HCCA, ACCA

2-Cyano-3-(4-hydroxyphenyl)propenoic acid

α-Cyano-4-hydroxybenzenepropenoic acid

alpha-Cyano-4-hydroxycinnamic acid,97%

α-CHCA

2-Cyano-3-(4-hydroxyphenyl)acrylic Acid alpha-CHCA

(E)-2-cyano-3-(4-hydroxyphenyl)acrylic acid

alpha-Cyano-4-hydroxycinnaMic acid 99%

2-Propenoic acid,2-cyano-3-(4-hydroxyphenyl)-

α-cyano-4-hydroxycinnamic acid(α-CHCA)

2-cyano-3-(4-hydroxyphenyl)prop-2-enoic acid

2-Cyano-3-(4-hydroxyphenyl)-2-propenoic acid

alpha-Cyano-4-hydroxycinnamic acid 28166-41-8

alpha-Cyano-4-hydroxycinnamic acid PRICE

α-Cyano-4-hydroxycinnamic Acid &gt

α-Cyano-4-hydroxycinnamic Acid

α-cyano-4-hydroxycinnamicaci

α-CCA

α-Cyano

alpha-Cyano-4-hydroxycinnamic acid, Ultrapure MALDI Matrix,

α-Cyano-4-hydroxycinnamic acid(α-CHCA)

α-CHCA

2-cyano-3-(4-hydroxyphenyl)prop-2-enoic acid (E)-2-cyano-3-(4-hydroxyphenyl)prop-2-enoic acid

28166-41-8

HOC6H4CHCCNCO2H

CARBOXYLIC ACID

Proteomics and Protein Expression

Protein Analysis

Matrices for MALDI Analysis

Organic Building Blocks

Matrix Materials (MALDI-TOF-MS)

Mass Spectrometry

Building Blocks

Analytical Reagents

Analytical Chromatography Product Catalog

BioChemical

Chiral

C10

Carboxylic Acids

Carbonyl Compounds

UltraPure MALDI Matrices

Analytical Chemistry

Mass Spectrometry

Matrix Materials (MALDI-TOF-MS)