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ALPHA-CYANO-4-HYDROXYCINNAMIC ACID

Product Name
ALPHA-CYANO-4-HYDROXYCINNAMIC ACID
CAS No.
28166-41-8
Chemical Name
ALPHA-CYANO-4-HYDROXYCINNAMIC ACID
Synonyms
α-Cyano-4-hydroxycinnamic Acid;ACCA;α-CHCA;A-CYANO-4-HYDROXYCINNAMIC ACID;α-CCA;4-HCCA;α-CHCA;α-Cyano;ALPHA-CCA;ALPHA-CHCA
CBNumber
CB0781327
Molecular Formula
C10H7NO3
Formula Weight
189.17
MOL File
28166-41-8.mol
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ALPHA-CYANO-4-HYDROXYCINNAMIC ACID Property

Melting point:
245-250 °C(lit.)
Boiling point:
324.41°C (rough estimate)
Density 
1.3175 (rough estimate)
refractive index 
1.5400 (estimate)
storage temp. 
2-8°C
solubility 
methanol: 10 mg/mL, clear
form 
powder
pka
0.85±0.10(Predicted)
color 
yellow
BRN 
3271427
InChIKey
AFVLVVWMAFSXCK-VMPITWQZSA-N
CAS DataBase Reference
28166-41-8(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
10-23
HS Code 
29269090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H317May cause an allergic skin reaction

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
70990
Product name
α-Cyano-4-hydroxycinnamic acid
Purity
matrixsubstanceforMALDI-MS,≥99.0%(HPLC)
Packaging
250mg
Price
$42.8
Updated
2024/03/01
Sigma-Aldrich
Product number
70990
Product name
α-Cyano-4-hydroxycinnamic acid
Purity
matrixsubstanceforMALDI-MS,≥99.0%(HPLC)
Packaging
1g
Price
$118
Updated
2024/03/01
Sigma-Aldrich
Product number
145505
Product name
α-Cyano-4-hydroxycinnamic acid
Purity
97%
Packaging
5g
Price
$73.9
Updated
2024/03/01
Sigma-Aldrich
Product number
39468
Product name
α-Cyano-4-hydroxycinnamic acid
Purity
matrixsubstanceforMALDI-MS,Ultrapure
Packaging
10x10mg
Price
$332
Updated
2024/03/01
Sigma-Aldrich
Product number
145505
Product name
α-Cyano-4-hydroxycinnamic acid
Purity
97%
Packaging
25g
Price
$97.2
Updated
2024/03/01
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ALPHA-CYANO-4-HYDROXYCINNAMIC ACID Chemical Properties,Usage,Production

Chemical Properties

yellow crystalline powder

Uses

inhibitor of mitochondrial pyruvate transport

Uses

α-Cyano-4-hydroxycinnamic acid (CHC) was used in encapsulation of CHC into NaY zeolite. It was used as matrix to investigate the activity of the paclitaxel derivatives using several well-established in vitro angiogenesis assays.

Uses

α-Cyano-4-hydroxycinnamic acid(CHC) was used as a matrix for peptides and nucleotides in mass spectroscopic analysis. It was used in encapsulation of CHC into NaY zeolite. It was used as matrix to investigate the activity of the paclitaxel derivatives using several well-established in vitro angiogenesis assays.

Definition

ChEBI: Alpha-cyano-4-hydroxycinnamic acid is a monohydroxycinnamic acid that is 4-hydroxycinnamic acid in which the hydrogen alpha- to the carboxy group is replaced by a cyano group. It is used as a matrix in matrix-assisted laser desorption/ionization (MALDI) mass spectrometry for the analysis of peptides and oligonucleotides. It has a role as a MALDI matrix material. It is a nitrile, a member of phenols and a monohydroxycinnamic acid.

General Description

α-Cyano-4-hydroxycinnamic acid is the commonly used matrix for analyzing peptides by matrix-assisted laser desorption/ionization mass spectrometry. It inhibits the monophenolase activity and diphenolase activity of mushroom tyrosinase.

Biochem/physiol Actions

α-Cyano-4-hydroxycinnamic acid acts as a specific inhibitor of monocarboxylic acid transport, including lactate and pyruvate transport. It is also reported to block β-cell apical anion exchange (IC50 of 2.4 mM).

storage

Store at +4°C

ALPHA-CYANO-4-HYDROXYCINNAMIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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ALPHA-CYANO-4-HYDROXYCINNAMIC ACID Suppliers

TOKYO CHEMICAL INDUSTRY CO., LTD.
Tel
03-36680489
Fax
03-3668-0520
Email
Sales-JP@TCIchemicals.com
Country
Japan
ProdList
28398
Advantage
80
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View Lastest Price from ALPHA-CYANO-4-HYDROXYCINNAMIC ACID manufacturers

Shanghai Qyubiotech Co., Ltd.
Product
a-Cyano-4-hydroxycinnamic acid 28166-41-8
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%+
Supply Ability
100000kg per Month
Release date
2023-08-25
Henan Fengda Chemical Co., Ltd
Product
ALPHA-CYANO-4-HYDROXYCINNAMIC ACID 28166-41-8
Price
US $10.00-2.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-04-28
Zhuozhou Wenxi import and Export Co., Ltd
Product
ALPHA-CYANO-4-HYDROXYCINNAMIC ACID 28166-41-8
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-08-11

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