ChemicalBook > CAS DataBase List > ALPHA-CYANO-4-HYDROXYCINNAMIC ACID
ALPHA-CYANO-4-HYDROXYCINNAMIC ACID
- Product Name
- ALPHA-CYANO-4-HYDROXYCINNAMIC ACID
- CAS No.
- 28166-41-8
- Chemical Name
- ALPHA-CYANO-4-HYDROXYCINNAMIC ACID
- Synonyms
- α-Cyano-4-hydroxycinnamic Acid;ACCA;α-CHCA;A-CYANO-4-HYDROXYCINNAMIC ACID;α-CCA;4-HCCA;α-Cyano;ALPHA-CCA;ALPHA-CHCA;ALPHA-CYANO
- CBNumber
- CB0781327
- Molecular Formula
- C10H7NO3
- Formula Weight
- 189.17
- MOL File
- 28166-41-8.mol
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ALPHA-CYANO-4-HYDROXYCINNAMIC ACID Property
- Melting point:
- 245-250 °C(lit.)
- Boiling point:
- 324.41°C (rough estimate)
- Density
- 1.3175 (rough estimate)
- refractive index
- 1.5400 (estimate)
- storage temp.
- 2-8°C
- solubility
- methanol: 10 mg/mL, clear
- form
- powder
- pka
- 0.85±0.10(Predicted)
- color
- yellow
- Water Solubility
- H2O: slightly soluble
methanol: water: soluble
polar organic solvents: soluble - BRN
- 3271427
- InChI
- InChI=1S/C10H7NO3/c11-6-8(10(13)14)5-7-1-3-9(12)4-2-7/h1-5,12H,(H,13,14)
- InChIKey
- AFVLVVWMAFSXCK-VMPITWQZSA-N
- SMILES
- C(O)(=O)C(C#N)=CC1=CC=C(O)C=C1
- CAS DataBase Reference
- 28166-41-8(CAS DataBase Reference)
- Absorption
- ≥2000 at 337nm (mol. absorption)
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H317May cause an allergic skin reaction
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- 70990
- Product name
- α-Cyano-4-hydroxycinnamic acid
- Purity
- matrixsubstanceforMALDI-MS,≥99.0%(HPLC)
- Packaging
- 250mg
- Price
- $45.1
- Updated
- 2025/07/31
Sigma-Aldrich
- Product number
- 70990
- Product name
- α-Cyano-4-hydroxycinnamic acid
- Purity
- matrixsubstanceforMALDI-MS,≥99.0%(HPLC)
- Packaging
- 1g
- Price
- $125
- Updated
- 2025/07/31
Sigma-Aldrich
- Product number
- 145505
- Product name
- α-Cyano-4-hydroxycinnamic acid
- Purity
- 97%
- Packaging
- 5g
- Price
- $72.39
- Updated
- 2025/07/31
Sigma-Aldrich
- Product number
- 39468
- Product name
- α-Cyano-4-hydroxycinnamic acid
- Purity
- matrixsubstanceforMALDI-MS,Ultrapure
- Packaging
- 10x10mg
- Price
- $349
- Updated
- 2025/07/31
Sigma-Aldrich
- Product number
- 145505
- Product name
- α-Cyano-4-hydroxycinnamic acid
- Purity
- 97%
- Packaging
- 25g
- Price
- $158.65
- Updated
- 2025/07/31
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ALPHA-CYANO-4-HYDROXYCINNAMIC ACID Chemical Properties,Usage,Production
Chemical Properties
yellow crystalline powder
Uses
inhibitor of mitochondrial pyruvate transport
Uses
α-Cyano-4-hydroxycinnamic acid (CHC) was used in encapsulation of CHC into NaY zeolite. It was used as matrix to investigate the activity of the paclitaxel derivatives using several well-established in vitro angiogenesis assays.
Uses
α-Cyano-4-hydroxycinnamic acid(CHC) was used as a matrix for peptides and nucleotides in mass spectroscopic analysis. It was used in encapsulation of CHC into NaY zeolite. It was used as matrix to investigate the activity of the paclitaxel derivatives using several well-established in vitro angiogenesis assays.
Definition
ChEBI: Alpha-cyano-4-hydroxycinnamic acid is a monohydroxycinnamic acid that is 4-hydroxycinnamic acid in which the hydrogen alpha- to the carboxy group is replaced by a cyano group. It is used as a matrix in matrix-assisted laser desorption/ionization (MALDI) mass spectrometry for the analysis of peptides and oligonucleotides. It has a role as a MALDI matrix material. It is a nitrile, a member of phenols and a monohydroxycinnamic acid.
General Description
α-Cyano-4-hydroxycinnamic acid is the commonly used matrix for analyzing peptides by matrix-assisted laser desorption/ionization mass spectrometry. It inhibits the monophenolase activity and diphenolase activity of mushroom tyrosinase.
Biochem/physiol Actions
α-Cyano-4-hydroxycinnamic acid acts as a specific inhibitor of monocarboxylic acid transport, including lactate and pyruvate transport. It is also reported to block β-cell apical anion exchange (IC50 of 2.4 mM).
storage
Store at +4°C
ALPHA-CYANO-4-HYDROXYCINNAMIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from ALPHA-CYANO-4-HYDROXYCINNAMIC ACID manufacturers
Shanghai Qyubiotech Co., Ltd.
- Product
- a-Cyano-4-hydroxycinnamic acid 28166-41-8
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%+
- Supply Ability
- 100000kg per Month
- Release date
- 2023-08-25
Henan Fengda Chemical Co., Ltd
- Product
- ALPHA-CYANO-4-HYDROXYCINNAMIC ACID 28166-41-8
- Price
- US $10.00-2.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-04-28
Zhuozhou Wenxi import and Export Co., Ltd
- Product
- ALPHA-CYANO-4-HYDROXYCINNAMIC ACID 28166-41-8
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-08-11
28166-41-8, ALPHA-CYANO-4-HYDROXYCINNAMIC ACIDRelated Search:
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