2-CYANO-3-HYDROXYPYRIDINE
- Product Name
- 2-CYANO-3-HYDROXYPYRIDINE
- CAS No.
- 932-35-4
- Chemical Name
- 2-CYANO-3-HYDROXYPYRIDINE
- Synonyms
- 3-hydroxy-2-cyanopy;2-Cyano-pyridin-3-ol;3-HYDROXYPICOLINONITRILE;2-Cyano-3-hydroxpyridine;3-hydroxy-2-cyanopyridine;2-CYANO-3-HYDROXYPYRIDINE;2-Cyano-3-hydroxypyridine >3-hydroxypyridin-2-carbonitril;3-Hydroxy-2-pyridinecarbonitrile;3-HYDROXY-PYRIDINE-2-CARBONITRILE
- CBNumber
- CB7330449
- Molecular Formula
- C6H4N2O
- Formula Weight
- 120.11
- MOL File
- 932-35-4.mol
2-CYANO-3-HYDROXYPYRIDINE Property
- Melting point:
- 211-212 °C (decomp)
- Boiling point:
- 429.2±30.0 °C(Predicted)
- Density
- 1.33±0.1 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,Room Temperature
- solubility
- DMSO (Sparingly), Methanol (Slightly)
- form
- Solid
- pka
- 2.58±0.10(Predicted)
- color
- Yellow to Dark Yellow
- InChI
- InChI=1S/C6H4N2O/c7-4-5-6(9)2-1-3-8-5/h1-3,9H
- InChIKey
- XTVFTOVNAKNVQK-UHFFFAOYSA-N
- SMILES
- C1(C#N)=NC=CC=C1O
- CAS DataBase Reference
- 932-35-4(CAS DataBase Reference)
Safety
- Hazard Codes
- T,Xi,Xn
- Risk Statements
- 20/21/22-36/37/38-41-37/38-22
- Safety Statements
- 26-36/37/39-39
- RIDADR
- 3439
- HazardClass
- IRRITANT
- PackingGroup
- Ⅲ
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- C1664
- Product name
- 2-Cyano-3-hydroxypyridine
- Purity
- >98.0%(GC)(T)
- Packaging
- 5g
- Price
- $253
- Updated
- 2025/07/31
- Product number
- C1664
- Product name
- 2-Cyano-3-hydroxypyridine
- Purity
- >98.0%(GC)(T)
- Packaging
- 25g
- Price
- $928
- Updated
- 2025/07/31
- Product number
- C987963
- Product name
- 2-Cyano-3-hydroxypyridine
- Packaging
- 100mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- C987963
- Product name
- 2-Cyano-3-hydroxypyridine
- Packaging
- 250mg
- Price
- $55
- Updated
- 2021/12/16
- Product number
- C987963
- Product name
- 2-Cyano-3-hydroxypyridine
- Packaging
- 500mg
- Price
- $65
- Updated
- 2021/12/16
2-CYANO-3-HYDROXYPYRIDINE Chemical Properties,Usage,Production
Uses
2-Cyano-3-hydroxypyridine can be used as eIF4A inhibitors.
Synthesis
62626-61-3
932-35-4
Example 3: 5.0 g of 1N hydrochloric acid and 1.0 g (6.31 mmol) of α-amino-2-furan acetonitrile hydrochloride were added to a three-neck flask at room temperature. The reaction mixture was cooled to 0 °C and 360 μL of bromine (6.94 mmol) was slowly added dropwise, followed by stirring at 0 °C for 1 hour. The reaction mixture was gradually warmed to room temperature and stirring was continued for 2 hours. After that, 32 μL of bromine was added to the reaction system and stirring was continued for 2 hours. Again, 32 μL of bromine was added and stirred for 1 hour. Upon completion of the reaction, 199 mg of sodium thiosulfate was added to the mixture to quench the reaction, followed by adjusting the pH with 40% NaOH aqueous solution to 3.0. The reaction mixture was filtered to afford a product containing 0.47 g of 2-cyano-3-hydroxypyridine. The yield of 2-cyano-3-hydroxypyridine was 62% based on the amount of α-amino-2-furylacetonitrile hydrochloride.
References
[1] Patent: TW2016/510, 2016, A. Location in patent: Page/Page column 14
[2] Patent: WO2017/127794, 2017, A1
[3] Patent: WO2017/127791, 2017, A1
[4] Patent: TW2018/27404, 2018, A
2-CYANO-3-HYDROXYPYRIDINE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-CYANO-3-HYDROXYPYRIDINE manufacturers
- Product
- 2-Cyano-3-hydroxypyridine 932-35-4
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 95.0%
- Supply Ability
- 1000kg
- Release date
- 2025-10-29
- Product
- 2-CYANO-3-HYDROXYPYRIDINE 932-35-4
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.0% min
- Supply Ability
- 100 tons min
- Release date
- 2021-05-13
- Product
- 2-Cyano-3-hydroxypyridine 932-35-4
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- 97-99.9%
- Supply Ability
- 20kgs/month
- Release date
- 2019-11-08