ChemicalBook > CAS DataBase List > 2-CYANO-3-HYDROXYPYRIDINE

2-CYANO-3-HYDROXYPYRIDINE

Product Name: 2-CYANO-3-HYDROXYPYRIDINE
CAS No.: 932-35-4
Chemical Name: 2-CYANO-3-HYDROXYPYRIDINE
Synonyms: 3-hydroxy-2-cyanopy;2-Cyano-pyridin-3-ol;3-HYDROXYPICOLINONITRILE;2-Cyano-3-hydroxpyridine;3-hydroxy-2-cyanopyridine;2-CYANO-3-HYDROXYPYRIDINE;2-Cyano-3-hydroxypyridine >3-hydroxypyridin-2-carbonitril;3-Hydroxy-2-pyridinecarbonitrile;3-HYDROXY-PYRIDINE-2-CARBONITRILE
CBNumber: CB7330449
Molecular Formula: C6H4N2O
Formula Weight: 120.11
MOL File: 932-35-4.mol

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2-CYANO-3-HYDROXYPYRIDINE Property

Melting point:: 211-212 °C (decomp)
Boiling point:: 429.2±30.0 °C(Predicted)
Density: 1.33±0.1 g/cm3(Predicted)
storage temp.: Inert atmosphere,Room Temperature
solubility: DMSO (Sparingly), Methanol (Slightly)
form: Solid
pka: 2.58±0.10(Predicted)
color: Yellow to Dark Yellow
InChI: InChI=1S/C6H4N2O/c7-4-5-6(9)2-1-3-8-5/h1-3,9H
InChIKey: XTVFTOVNAKNVQK-UHFFFAOYSA-N
SMILES: C1(C#N)=NC=CC=C1O
CAS DataBase Reference: 932-35-4(CAS DataBase Reference)

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Safety

Hazard Codes: T,Xi,Xn
Risk Statements: 20/21/22-36/37/38-41-37/38-22
Safety Statements: 26-36/37/39-39
RIDADR: 3439
HazardClass: IRRITANT
PackingGroup: Ⅲ
HS Code: 2933399990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical

Product number: C1664
Product name: 2-Cyano-3-hydroxypyridine
Purity: >98.0%(GC)(T)
Packaging: 5g
Price: $253
Updated: 2025/07/31

TCI Chemical

Product number: C1664
Product name: 2-Cyano-3-hydroxypyridine
Purity: >98.0%(GC)(T)
Packaging: 25g
Price: $928
Updated: 2025/07/31

TRC

Product number: C987963
Product name: 2-Cyano-3-hydroxypyridine
Packaging: 100mg
Price: $45
Updated: 2021/12/16

TRC

Product number: C987963
Product name: 2-Cyano-3-hydroxypyridine
Packaging: 250mg
Price: $55
Updated: 2021/12/16

TRC

Product number: C987963
Product name: 2-Cyano-3-hydroxypyridine
Packaging: 500mg
Price: $65
Updated: 2021/12/16

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2-CYANO-3-HYDROXYPYRIDINE Chemical Properties,Usage,Production

Uses

2-Cyano-3-hydroxypyridine can be used as eIF4A inhibitors.

Synthesis

62626-61-3

932-35-4

Example 3: 5.0 g of 1N hydrochloric acid and 1.0 g (6.31 mmol) of α-amino-2-furan acetonitrile hydrochloride were added to a three-neck flask at room temperature. The reaction mixture was cooled to 0 °C and 360 μL of bromine (6.94 mmol) was slowly added dropwise, followed by stirring at 0 °C for 1 hour. The reaction mixture was gradually warmed to room temperature and stirring was continued for 2 hours. After that, 32 μL of bromine was added to the reaction system and stirring was continued for 2 hours. Again, 32 μL of bromine was added and stirred for 1 hour. Upon completion of the reaction, 199 mg of sodium thiosulfate was added to the mixture to quench the reaction, followed by adjusting the pH with 40% NaOH aqueous solution to 3.0. The reaction mixture was filtered to afford a product containing 0.47 g of 2-cyano-3-hydroxypyridine. The yield of 2-cyano-3-hydroxypyridine was 62% based on the amount of α-amino-2-furylacetonitrile hydrochloride.

References

[1] Patent: TW2016/510, 2016, A. Location in patent: Page/Page column 14
[2] Patent: WO2017/127794, 2017, A1
[3] Patent: WO2017/127791, 2017, A1
[4] Patent: TW2018/27404, 2018, A

2-CYANO-3-HYDROXYPYRIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

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2-CYANO-3-HYDROXYPYRIDINE Suppliers

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View Lastest Price from 2-CYANO-3-HYDROXYPYRIDINE manufacturers

Shanghai Joiny Pharmaceutical Co.,LTD

Product: 2-Cyano-3-hydroxypyridine 932-35-4
Price: US $0.00/kg
Min. Order: 1kg
Purity: 95.0%
Supply Ability: 1000kg
Release date: 2025-10-29

Shaanxi Dideu Medichem Co. Ltd

Product: 2-CYANO-3-HYDROXYPYRIDINE 932-35-4
Price: US $1.10/g
Min. Order: 1g
Purity: 99.0% min
Supply Ability: 100 tons min
Release date: 2021-05-13

Nanjing jinheyou Trading Co., Ltd.

Product: 2-Cyano-3-hydroxypyridine 932-35-4
Price: US $0.00/g
Min. Order: 1g
Purity: 97-99.9%
Supply Ability: 20kgs/month
Release date: 2019-11-08

932-35-4, 2-CYANO-3-HYDROXYPYRIDINERelated Search:

2-CYANO-3-HYDROXYPYRIDINE 4-CYANO-2-HYDROXYPYRIDINE 5-CYANO-2-HYDROXYPYRIDINE,3-CYANO-6-HYDROXYPYRIDINE,3-CYANO-6-HYDROXYPYRIDINE / 2-HYDROXY-5-CYANOPYRIDINE 2-Hydroxypyridine-3-carbonitrile, 3-Cyano-2-hydroxypyridine 2-CYANO-5-HYDROXYPYRIDINE ETHYL 6-(TERT-BUTYL)-3-CYANO-2-HYDROXYPYRIDINE-4-CARBOXYLATE 3-Cyano-2-hydroxypyridine 5-BROMO-3-CYANO-2-HYDROXYPYRIDINE,5-Bromo-3-cyano-2-hydroxypyridine 98% 2-CYANO-3-METHOXYPYRIDINE 2-Cyano-6-hydroxypyridine 4-Oxo-1,4-dihydro-pyridine-3-carbonitrile 3-Cyano-5-Hydroxypyridine 3-(3-PYRIDINYLMETHOXY)-5-(TRIFLUOROMETHYL)-2-PYRIDINECARBONITRILE 3-(4-[3-(DIMETHYLAMINO)ACRYLOYL]PHENOXY)-5-(TRIFLUOROMETHYL)-2-PYRIDINECARBONITRILE 3-(4-CHLOROPHENOXY)-5-(TRIFLUOROMETHYL)-2-PYRIDINECARBONITRILE 3-(8-QUINOLINYLOXY)-5-(TRIFLUOROMETHYL)-2-PYRIDINECARBONITRILE 3-(4-METHOXYPHENOXY)-5-(TRIFLUOROMETHYL)-2-PYRIDINECARBONITRILE 3-methoxy-5-(trifluoromethyl)-2-pyridinecarbonitrile

2-CYANO-3-HYDROXYPYRIDINE

3-HYDROXY-PYRIDINE-2-CARBONITRILE

3-HYDROXYPICOLINONITRILE

2-[(2,2-dimethyl-1-oxopropyl)amino]ethanesulfonic acid

3-hydroxy-2-cyanopyridine

2-Cyano-3-hydroxpyridine

3-hydroxy-2-cyanopy

2-Cyano-pyridin-3-ol

3-Hydroxy-2-pyridinecarbonitrile

2-Cyano-3-hydroxypyridine &gt

2-Pyridinecarbonitrile, 3-hydroxy-

2-CYANO-3-HYDROXYPYRIDINE ISO 9001：2015 REACH

3-hydroxypyridin-2-carbonitril

932-35-4

463932-35-4

Heterocycle-Pyridine series

Pyridine

Heterocyclic Compounds

Pyridine series

pharmacetical