Isobutyrophenone
- Product Name
- Isobutyrophenone
- CAS No.
- 611-70-1
- Chemical Name
- Isobutyrophenone
- Synonyms
- ISOPROPYL PHENYL KETONE;1-Propanone, 2-methyl-1-phenyl-;ISOBUTROPHENONE;sobutyrophenone;ISOBUTYROPHENONE;lsobutyrophenone;ISOBUTYRYLBENZENE;Isobutyrophenone>Isobutyrophenone 97%;Isobutyrophenone,97%
- CBNumber
- CB1180914
- Molecular Formula
- C10H12O
- Formula Weight
- 148.2
- MOL File
- 611-70-1.mol
Isobutyrophenone Property
- Melting point:
- 1 °C
- Boiling point:
- 217 °C (lit.)
- Density
- 0.988 g/mL at 25 °C (lit.)
- vapor pressure
- 1 mm Hg ( 50 °C)
- refractive index
- n20/D 1.517(lit.)
- Flash point:
- 184 °F
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- Chloroform (Sparingly), Methanol (Slightly)
- form
- Oil
- color
- Colourless
- Water Solubility
- immiscible
- BRN
- 774499
- LogP
- 2.73
- CAS DataBase Reference
- 611-70-1(CAS DataBase Reference)
- NIST Chemistry Reference
- Isopropyl phenyl ketone(611-70-1)
- EPA Substance Registry System
- 1-Propanone, 2-methyl-1-phenyl- (611-70-1)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 130362
- Product name
- Isobutyrophenone
- Purity
- 97%
- Packaging
- 25g
- Price
- $18.72
- Updated
- 2024/03/01
- Product number
- 130362
- Product name
- Isobutyrophenone
- Purity
- 97%
- Packaging
- 100g
- Price
- $37.6
- Updated
- 2024/03/01
- Product number
- I0113
- Product name
- Isobutyrophenone
- Purity
- >98.0%(GC)
- Packaging
- 25mL
- Price
- $42
- Updated
- 2024/03/01
- Product number
- I0113
- Product name
- Isobutyrophenone
- Purity
- >98.0%(GC)
- Packaging
- 500mL
- Price
- $243
- Updated
- 2024/03/01
- Product number
- B24628
- Product name
- Isobutyrophenone, 97%
- Packaging
- 25g
- Price
- $42.65
- Updated
- 2024/03/01
Isobutyrophenone Chemical Properties,Usage,Production
Chemical Properties
clear colorless to very slightly yellow liquid
Uses
Isobutyrophenone is used as an internal standard in the determination of hydroxyzine hydrochloride and benzyl alcohol in injection solutions. It is also used in the preparation of alpha-hydroxyisobutyrophenone. Isobutyrophenone is employed as photosensitizer intermediate. It can react with bromoacetic acid ethyl ester to get 3-hydroxy-4-methyl-3-phenyl-valeric acid ethyl ester.
Preparation
Isobutyrophenone synthesis: Benzene underwent a Friedel–Crafts acylation with isobutyryl chloride to synthesize isobutyrophenone. The reaction was performed using excess benzene as a replacement for a typical solvent and heat to reflux (88 °C) for a period of 3 hours. Any unreacted benzene was recovered after the reaction during the distillation process. A 66 % yield of isobutyrophenone was obtained from the solar synthesis, compared to a 44 % yield from an in-lab, electrical heating analysis.
Synthesis Reference(s)
Journal of the American Chemical Society, 71, p. 1061, 1949 DOI: 10.1021/ja01171a084
The Journal of Organic Chemistry, 32, p. 404, 1967 DOI: 10.1021/jo01288a032
Tetrahedron Letters, 14, p. 2491, 1973
Flammability and Explosibility
Non flammable
Isobutyrophenone Preparation Products And Raw materials
Raw materials
Preparation Products
Isobutyrophenone Suppliers
View Lastest Price from Isobutyrophenone manufacturers
- Product
- Isobutyrophenone 611-70-1
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-08-11
- Product
- Isobutyrophenone 611-70-1
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 10000KGS
- Release date
- 2020-01-10