(S)-1-N-Boc-2-(aminomethyl)pyrrolidine
- Product Name
- (S)-1-N-Boc-2-(aminomethyl)pyrrolidine
- CAS No.
- 119020-01-8
- Chemical Name
- (S)-1-N-Boc-2-(aminomethyl)pyrrolidine
- Synonyms
- (S)-1-BOC-2-(AMINOMETHYL)PYRROLIDINE;-1-Boc-pyrroL;CAS:119020-01-8;(S)-2-AminomethyL;RARECHEM AL BW 2320;(S)-1-Boc-2-(aminomethyl)...;(S)-N'-BOC-2-Aminomethylpirrolidine;(S)-2-AMINOMETHYL-1-BOC-PYRROLIDINE;(S)-N-Boc-2-(aminomethyl)pyrrolidine;(s)-1-Boc-2-(AMinoMethyl ) Pyrolidine
- CBNumber
- CB1184725
- Molecular Formula
- C10H20N2O2
- Formula Weight
- 200.28
- MOL File
- 119020-01-8.mol
(S)-1-N-Boc-2-(aminomethyl)pyrrolidine Property
- Boiling point:
- 98-112℃/1mm
- Density
- 1.044±0.06 g/cm3(Predicted)
- refractive index
- 1.4670-1.4710
- storage temp.
- 2-8°C
- solubility
- Miscible with N-methylpyrrolidinone.
- pka
- 9.91±0.29(Predicted)
- form
- clear liquid
- color
- Colorless to Almost colorless
- BRN
- 8905233
- CAS DataBase Reference
- 119020-01-8(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi,N,C
- Risk Statements
- 36/37/38-51/53-34-22
- Safety Statements
- 26-36/37/39-61-45
- RIDADR
- 3259
- WGK Germany
- 3
- HazardClass
- 8
- PackingGroup
- Ⅲ
- HS Code
- 29339900
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H302Harmful if swallowed
H314Causes severe skin burns and eye damage
- Precautionary statements
-
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- A2473
- Product name
- (S)-2-(Aminomethyl)-1-(tert-butoxycarbonyl)pyrrolidine
- Purity
- >98.0%(GC)(T)
- Packaging
- 1g
- Price
- $140
- Updated
- 2025/07/31
- Product number
- B702248
- Product name
- (S)-1-Boc-2-(aminomethyl)pyrrolidine
- Packaging
- 2.5g
- Price
- $110
- Updated
- 2021/12/16
- Product number
- 41567
- Product name
- (S)-2-(Aminomethyl)-1-Boc-pyrrolidine,98%(GC)
- Purity
- 98%(GC)
- Packaging
- 100MG
- Price
- $70
- Updated
- 2021/12/16
- Product number
- K815
- Product name
- (S)-1-N-Boc-2-(aminomethyl)pyrrolidine
- Packaging
- 5g
- Price
- $147
- Updated
- 2021/12/16
- Product number
- AS3151
- Product name
- (S)-N-Boc-2-(aminomethyl)pyrrolidine
- Purity
- 97+% ee
- Packaging
- 5G
- Price
- $151
- Updated
- 2021/12/16
(S)-1-N-Boc-2-(aminomethyl)pyrrolidine Chemical Properties,Usage,Production
Chemical Properties
Solid
Uses
(S)-2-Aminomethyl-1-Boc-pyrrolidine acts as an intermediate in organic synthesis. It is also used as a chiral and heterocyclic building block in synthetic chemistry.
Synthesis
168049-26-1
119020-01-8
GENERAL METHOD: Under stirring conditions, azide derivatives 9a or 9b (4.03 mmol) were dissolved in THF (1 mL), followed by the addition of solid triphenylphosphine (Ph3P, 4.03 mmol) and water (H2O, 6.04 mmol). The reaction mixture was stirred continuously for 12 h at room temperature. After completion of the reaction, the solvent was removed by concentration under reduced pressure. The crude product was purified by rapid column chromatography on silica gel with an eluent ratio of methanol-dichloromethane (9:1).
References
[1] Synthesis, 2005, # 14, p. 2407 - 2413
[2] Angewandte Chemie - International Edition, 2011, vol. 50, # 48, p. 11382 - 11385
[3] Synthetic Communications, 2011, vol. 41, # 17, p. 2517 - 2523
[4] Tetrahedron Letters, 2010, vol. 51, # 40, p. 5281 - 5286
[5] Phosphorus, Sulfur and Silicon and the Related Elements, 2013, vol. 188, # 4, p. 509 - 511
(S)-1-N-Boc-2-(aminomethyl)pyrrolidine Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from (S)-1-N-Boc-2-(aminomethyl)pyrrolidine manufacturers
- Product
- (S)-1-Boc-2-(aminomethyl)pyrrolidine 119020-01-8
- Price
- US $1.10-9.90/kg
- Min. Order
- 1kg
- Purity
- 99%min
- Supply Ability
- 100kg
- Release date
- 2025-08-18
- Product
- (S)-1-N-Boc-2-(aminomethyl)pyrrolidine 119020-01-8
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 500000kg
- Release date
- 2024-10-30
- Product
- (S)-1-N-Boc-2-(aminomethyl)pyrrolidine 119020-01-8
- Price
- US $40.00/kg
- Min. Order
- 1kg
- Purity
- 0.99
- Supply Ability
- 10 tons
- Release date
- 2023-10-08