alamifovir

Product Name: alamifovir
CAS No.: 193681-12-8
Chemical Name: alamifovir
Synonyms: MCC 478;LY 582563;alamifovir;Alamifovir (MCC-478);P-[[2-[2-Amino-6-[(4-methoxyphenyl)thio]-9H-purin-9-yl]ethoxy]methyl]phosphonic acid bis(2,2,2-trifluoroethyl) ester;Phosphonic acid, P-[[2-[2-amino-6-[(4-methoxyphenyl)thio]-9H-purin-9-yl]ethoxy]methyl]-, bis(2,2,2-trifluoroethyl) ester
CBNumber: CB11856021
Molecular Formula: C19H20F6N5O5PS
Formula Weight: 575.42
MOL File: 193681-12-8.mol

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alamifovir Property

Melting point:: 84-85℃
Boiling point:: 671.5±65.0 °C(Predicted)
Density: 1.60
form: Solid
pka: 2?+-.0.10(Predicted)
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation

Product number: API0019247
Product name: ALAMIFOVIR
Purity: 95.00%
Packaging: 5MG
Price: $505.59
Updated: 2021/12/16

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alamifovir Chemical Properties,Usage,Production

Uses

Alamifovir (LY582563; MCC-478), a purine nucleotide analogue proagent, shows potent activity against wild type and lamivudine resistant hepatitis B virus (HBV). Alamifovir has high activity against HBV replication and sustained antiviral effect[1][2].

References

[1] Suzane Kioko Ono-Nita, et al. Novel nucleoside analogue MCC-478 (LY582563) is effective against wild-type or lamivudine-resistant hepatitis B virus. Antimicrob Agents Chemother. 2002 Aug;46(8):2602-5. DOI:10.1128/AAC.46.8.2602-2605.2002
[2] Danny K W Soon, et al. Safety and efficacy of alamifovir in patients with chronic hepatitis B virus infection. J Hepatol. 2004 Nov;41(5):852-8. DOI:10.1016/j.jhep.2004.07.028

alamifovir Preparation Products And Raw materials

Raw materials

Preparation Products

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alamifovir Suppliers

China 6 United States 3 Global 9

Guangzhou Jhd Chemical Reagent Co., Ltd.

Tel: 020-84383047
Fax: 020-84380294
Email: sales@jhd.com.cn
Country: China
ProdList: 9186
Advantage: 65

TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 32435
Advantage: 58

CONIER CHEM AND PHARMA LIMITED

Tel: +8618523575427
Email: sales@conier.com
Country: China
ProdList: 49975
Advantage: 58

Chengdu Peter-like Biotechnology Co., Ltd.

Tel: 028-81700200 13308200041
Email: 2851167782@qq.com
Country: China
ProdList: 11146
Advantage: 58

Biosynth Biological Technology (Suzhou) Co Ltd

Tel: 51288865780
Email: sales@biosynth.com
Country: China
ProdList: 6051
Advantage: 58

Shanghai YanyiBao Pharmaceutical Technology Co., Ltd.

Tel: 13661744693
Email: wangyue@yybyy.com
Country: China
ProdList: 598
Advantage: 58

Shanghai meikai technology co., ltd

Tel: 021-68689288 15300790979
Fax: wechat 18721550091
Email: info@mkbio.com.cn
Country: China
ProdList: 5000
Advantage: 58

193681-12-8, alamifovirRelated Search:

Velpatasvir Aladdin reagent 6-Thioguanine alamifovir 6-Methylthioguanine BIS(2,2,2-TRIFLUOROETHYL) PHOSPHITE 6-(Phenylthio)purine

LY 582563

P-[[2-[2-Amino-6-[(4-methoxyphenyl)thio]-9H-purin-9-yl]ethoxy]methyl]phosphonic acid bis(2,2,2-trifluoroethyl) ester

alamifovir

MCC 478

Alamifovir (MCC-478)

Phosphonic acid, P-[[2-[2-amino-6-[(4-methoxyphenyl)thio]-9H-purin-9-yl]ethoxy]methyl]-, bis(2,2,2-trifluoroethyl) ester

193681-12-8

C19H20F6N5O5PS