Uses
ChemicalBook > CAS DataBase List > 4-METHYL-2,2'-BIPYRIDINE

4-METHYL-2,2'-BIPYRIDINE

Uses
Product Name
4-METHYL-2,2'-BIPYRIDINE
CAS No.
56100-19-7
Chemical Name
4-METHYL-2,2'-BIPYRIDINE
Synonyms
4-methyl-2,2'-dipyridyl;4-METHYL-2,2'-BIPYRIDINE;4-Methyl-2,2'-bipyridine;2,2'-bipyridine, 4-methyl-;4-Methyl-[2,2']bipyridinyl;4-methyl-2-pyridin-2-ylpyridine;2-(4-methylpyridin-2-yl)pyridine
CBNumber
CB1186446
Molecular Formula
C11H10N2
Formula Weight
170.21
MOL File
56100-19-7.mol
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4-METHYL-2,2'-BIPYRIDINE Property

Melting point:
62-64 °C(Solv: ligroine (8032-32-4))
Boiling point:
296.6±25.0 °C(Predicted)
Density 
1.081±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
pka
4.73±0.18(Predicted)
Appearance
White to off-white Solid
InChI
InChI=1S/C11H10N2/c1-9-5-7-13-11(8-9)10-4-2-3-6-12-10/h2-8H,1H3
InChIKey
OHSRAWAUPZWNKY-UHFFFAOYSA-N
SMILES
C1(C2=NC=CC=C2)=NC=CC(C)=C1
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Safety

HS Code 
9999999999
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Rieke Metals
Product number
11145
Product name
4-Methyl-2,2'-bipyridine
Purity
97%
Packaging
1g
Price
$355
Updated
2021/12/16
Matrix Scientific
Product number
106102
Product name
4-Methyl-[2,2']bipyridinyl
Purity
97%
Packaging
1g
Price
$385
Updated
2021/12/16
Rieke Metals
Product number
11145
Product name
4-Methyl-2,2'-bipyridine
Purity
97%
Packaging
2g
Price
$490
Updated
2021/12/16
Matrix Scientific
Product number
106102
Product name
4-Methyl-[2,2']bipyridinyl
Purity
97%
Packaging
2g
Price
$500
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0075432
Product name
4-METHYL-[2,2']BIPYRIDINYL
Purity
95.00%
Packaging
1G
Price
$958.07
Updated
2021/12/16
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4-METHYL-2,2'-BIPYRIDINE Chemical Properties,Usage,Production

Uses

4-Methyl-2,2'-bipyridine is a useful compound for research.

Synthesis

2732-35-6

56100-19-7

Example 2 Synthesis of 4-methyl-2-(2'-pyridinyl)pyridine: Tetrahydrofuran (10 ml) and isopropylmagnesium chloride (2.0 M, 7.7 ml, 15.5 mmol) were added to a 50 ml flask under nitrogen protection. Subsequently, a solution prepared from 2-bromopyridine (2.45 g, 15.5 mmol) dissolved in tetrahydrofuran (3 ml) was added slowly and dropwise over 10 min. The reaction mixture was stirred for 1 hour and then a solution prepared from 4-methyl-2-benzenesulfonylpyridine (3.00 g, 12.9 mmol) dissolved in tetrahydrofuran (5 ml) was added dropwise over 10 minutes. The reaction mixture was continued to be stirred at room temperature for 5 h. Isopropanol (1 ml) was added at the termination of the reaction. The reaction mixture was poured into water and extracted with ethyl acetate (15 ml x 2). The organic phases were combined, concentrated and purified by silica gel column chromatography to afford the target product 4-methyl-2,2'-bipyridine (1.51 g, 89% yield, based on 4-methyl-2-phenylsulfonylpyridine) as a white solid. The product was characterized by 1H-NMR (CDCl3): δ 2.36 (s, 3H), 7.06 (d, 1H, J = 5.0 Hz), 7.20-7.25 (m, 1H), 7.69-7.74 (m, 1H), 8.16 (s, 1H), 8.32 (d, 1H, J = 8.0 Hz), 8.46 (d, 1H, J = 4.6 Hz) , 8.57-8.63 (m, 1H).

References

[1] Patent: EP1548005, 2005, A1. Location in patent: Page/Page column 11

4-METHYL-2,2'-BIPYRIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

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4-METHYL-2,2'-BIPYRIDINE Suppliers

Shanghai UCHEM Inc.
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18939844854
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China
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Henan Lien Chemical Products Co., Ltd.
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Shanghai Hanhong Scientific Co.,Ltd.
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Bide Pharmatech Ltd.
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Shanghai Uchem Inc.
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NanJing Xienuo bio Co.,Ltd.
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View Lastest Price from 4-METHYL-2,2'-BIPYRIDINE manufacturers

Shanghai UCHEM Inc.
Product
4-Methyl-2,2'-bipyridine 56100-19-7
Price
US $232.00-878.00/g
Min. Order
1g
Purity
0.98
Supply Ability
10kg
Release date
2024-04-12
Career Henan Chemical Co
Product
4-METHYL-2,2'-BIPYRIDINE 56100-19-7
Price
US $1.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
100KG
Release date
2019-08-07