4-Bromoindole-2-carboxylic acid methyl ester
- Product Name
- 4-Bromoindole-2-carboxylic acid methyl ester
- CAS No.
- 167479-13-2
- Chemical Name
- 4-Bromoindole-2-carboxylic acid methyl ester
- Synonyms
- Methyl 4-bromoindole-2-carboxylate;Methyl 4-bromo-1H-indole-2-carboxylate 98%;4-Bromoindole-2-carboxylic acid methyl ester;4-bromo-1H-indole-2-carboxylic acid methyl ester;methyl 4-bromo-1H-indole-2-carboxylate - [M83515];1H-Indole-2-carboxylic acid, 4-broMo-, Methyl ester
- CBNumber
- CB11876678
- Molecular Formula
- C10H8BrNO2
- Formula Weight
- 254.08
- MOL File
- 167479-13-2.mol
4-Bromoindole-2-carboxylic acid methyl ester Property
- Boiling point:
- 386.2±22.0 °C(Predicted)
- Density
- 1.629±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 14.04±0.30(Predicted)
- form
- solid
- color
- Beige
Safety
- HazardClass
- IRRITANT
- HS Code
- 2924297099
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
N-Bromosuccinimide Price
- Product number
- CS-0037917
- Product name
- Methyl4-bromo-1H-indole-2-carboxylate
- Purity
- 98.07%
- Packaging
- 100mg
- Price
- $15
- Updated
- 2021/12/16
- Product number
- CS-0037917
- Product name
- Methyl4-bromo-1H-indole-2-carboxylate
- Purity
- 98.07%
- Packaging
- 250mg
- Price
- $21
- Updated
- 2021/12/16
- Product number
- CS-0037917
- Product name
- Methyl4-bromo-1H-indole-2-carboxylate
- Purity
- 98.07%
- Packaging
- 1g
- Price
- $48
- Updated
- 2021/12/16
- Product number
- 4H23-9-0B
- Product name
- Methyl 4-bromo-1H-indole-2-carboxylate
- Purity
- 98%
- Packaging
- 1g
- Price
- $170
- Updated
- 2021/12/16
- Product number
- CS-0037917
- Product name
- Methyl4-bromo-1H-indole-2-carboxylate
- Purity
- 98.07%
- Packaging
- 5g
- Price
- $209
- Updated
- 2021/12/16
4-Bromoindole-2-carboxylic acid methyl ester Chemical Properties,Usage,Production
Synthesis
220448-44-2
167479-13-2
GENERAL METHOD: Methyl 3-aryl-2-azidoacrylate (20.0 mmol) was added in a single addition to a pre-heated to reflux xylene solution (75 mL) and the reaction was kept at reflux for 2 hours. Upon completion of the reaction, the solvent was removed by rotary evaporator. The resulting residue was purified by silica gel column chromatography with mixed petroleum ether/ethyl acetate solvent as eluent. The synthesis of compounds 12, 18 and 19 has been reported in the literature [9b, 13, 14].
References
[1] European Journal of Medicinal Chemistry, 2012, vol. 49, p. 379 - 396
4-Bromoindole-2-carboxylic acid methyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
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