ChemicalBook > CAS DataBase List > (R)-(+)-Dropropizine

(R)-(+)-Dropropizine

Product Name
(R)-(+)-Dropropizine
CAS No.
99291-24-4
Chemical Name
(R)-(+)-Dropropizine
Synonyms
Brn 3592398;d-Dropropizine;Levdropropizina;Levodropropizine;(S)-Dropropizine;(+)-Dropropizine;Dextrodropropizine;Dropropizine S-form;Levodropropizine API;(R)-(+)-Dropropizine
CBNumber
CB1191439
Molecular Formula
C13H20N2O2
Formula Weight
236.31
MOL File
99291-24-4.mol
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(R)-(+)-Dropropizine Property

Melting point:
98-100°
alpha 
D25 -10° (c = 1.0 in ethanol)
Boiling point:
412.7±34.0 °C(Predicted)
Density 
1.168±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
Acetonitrile (Slightly), Methanol (Slightly)
pka
14.21±0.20(Predicted)
color 
White to Off-White
CAS DataBase Reference
99291-24-4(CAS DataBase Reference)
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Safety

Toxicity
LD50 in mice, rats (mg/kg): 1287.2, 886.6 orally; 408.0, 401.3 i.p. (Borsa)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
L0420002
Product name
Levodropropizine impurity A
Purity
European Pharmacopoeia (EP) Reference Standard
Packaging
l0420002
Price
$153
Updated
2024/03/01
TRC
Product number
D681505
Product name
(R)-(+)-Dropropizine
Packaging
100mg
Price
$185
Updated
2021/12/16
TRC
Product number
D681505
Product name
(R)-(+)-Dropropizine
Packaging
1g
Price
$1455
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CCH0000694
Product name
(2R)-3-(4-PHENYL-1-PIPERAZINYL)-1,2-PROPANEDIOL
Purity
95.00%
Packaging
1G
Price
$1963.5
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0026345
Product name
(R)-(+)-DROPROPIZINE
Purity
95.00%
Packaging
5MG
Price
$501.17
Updated
2021/12/16
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(R)-(+)-Dropropizine Chemical Properties,Usage,Production

Description

Levodropropizine is an antitussive with antiinflammatory activity, the L-isomer of dropropizine. Compared with the racemate, levodropropizine is reported to have less sedative potential and better therapeutic index, while maintaining the the same efficacy levels as an antitussive and antiinflammatory.

Originator

Dompe (Italy)

Uses

receptor agonist, treatment of colds and allergic rhinitis

Uses

R-Form of Dropropizine (D681495). (R)-(+)-Dropropizine is a cough suppressive phenylpiperazine derivative. (R)-(+)-Dropropizine is an antitussive and central sedative therapeutic agent.

brand name

Levotus

(R)-(+)-Dropropizine Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from (R)-(+)-Dropropizine manufacturers

Hebei Ningnan Trade Co. LTD
Product
Levodropropizine 99291-24-4
Price
US $80.00/KG
Min. Order
0.1KG
Purity
99.99%
Supply Ability
1000kg
Release date
2022-11-02
Dideu Industries Group Limited
Product
(R)-(+)-Dropropizine 99291-24-4
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons
Release date
2022-02-24
Shaanxi Dideu Medichem Co. Ltd
Product
Levodropropizine 99291-24-4
Price
US $0.10/KG
Min. Order
1KG
Purity
99.0%
Supply Ability
1000 tons
Release date
2020-04-28

99291-24-4, (R)-(+)-DropropizineRelated Search:

2-Ethylhexyl ferulate Phenylhydrazine 2-METHYL-1,3-PROPANEDIOL Dropropizine 1-Methoxy-2-propyl acetate Poly(propylene glycol) Propylene glycol (R)-(-)-1,2-Propanediol Hydroxypropyl methyl cellulose N-Aminoethylpiperazine Diprophylline PHENYL VALERATE 1-Phenoxy-2-propanol Hydroxypropyl cellulose 1-Methoxy-2-propanol Levonorgestrel Levosimendan Potassium (R)-[(3-ethoxy-1-methyl-3-oxoprop-1-enyl)amino]phenylacetate

  • (2R)-3-(4-phenyl-1-piperazinyl)propane-1,2-diol
  • Levodropropizine ImpurityⅠ:dextrodropropizine
  • (S)-Dropropizine
  • (S)-3-(4-Phenyl-1-piperazinyl)-1,2-propanediol
  • Levodropropizine
  • (2R)-3-(4-Phenyl-1-piperazinyl)-1,2-propanediol
  • (R)-(+)-Dropropizine
  • d-Dropropizine
  • Dextrodropropizine
  • Levodropropizine API
  • (R)-3-(4-Phenyl-1-piperazinyl)-1,2-propanediol
  • 1,2-Propanediol, 3-(4-phenyl-1-piperazinyl)-, (R)-
  • Brn 3592398
  • Dropropizine S-form
  • Levdropropizina
  • Levdropropizina [latin,spanish]
  • Medroxyprogesterone Acetate IMp. F (EP)
  • Levodropropizine USP
  • (R)-3-(4-Phenylpiperazin-1-yl)propane-1,2-diol
  • (2R)-3-(4-Phenylpiperazin-1-yl)propane-1,2-diol
  • Levodropropizine (S)-3-(4-Phenyl-1-piperazinyl)-1,2-propanediol
  • Levodropropizine EP Impurity A(Dextrodropropizine)
  • Levodropropizine EP Impurity A
  • 1,2-Propanediol, 3-(4-phenyl-1-piperazinyl)-, (2R)-
  • 17-(Acetyloxy)-6α-methyl-5β-pregnane-3,20-dione
  • (+)-Dropropizine
  • (R)-(+)-Dropropizine ISO 9001：2015 REACH
  • Levodropropizine EP Impurity A (Dextrodropropizine/ Dropropizine R-Isomer)
  • Levodropropizine ImpurityⅠ:dextrodropropizine
  • (R)-3-(4-Phenylpiperazin-1-yl)propane-1,2-diol (Levodropropizine Impurity)
  • 99291-24-4
  • 99291-25-1
  • Aromatics
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • API