Dropropizine

Product Name: Dropropizine
CAS No.: 17692-31-8
Chemical Name: Dropropizine
Synonyms: ribex;katril;larylin;catabex;UCB-196;ditustat;tussilex;gevotuss;UCB-1967;dopropizin
CBNumber: CB9328471
Molecular Formula: C13H20N2O2
Formula Weight: 236.31
MOL File: 17692-31-8.mol

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Dropropizine Property

Melting point:: 105° (Morren); mp 108° (Bourdais)
Boiling point:: 205 °C(Press: 1 Torr)
Density: 1.168±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
solubility: Chloroform (Sparingly), Methanol (Slightly)
pka: 14.21±0.20(Predicted)
color: White to Off-White
CAS DataBase Reference: 17692-31-8(CAS DataBase Reference)

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Safety

Hazard Codes: Xn
Risk Statements: 22
Safety Statements: 36
WGK Germany: 3
RTECS: TZ1074800
Toxicity: LD50 in rats (mg/kg): 200 i.v., 750 orally (Morren)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: D4285
Product name: (±)-Dropropizine
Purity: analytical standard, for drug analysis
Packaging: 5g
Price: $55.7
Updated: 2022/05/15

TRC

Product number: D681495
Product name: racDropropizine
Packaging: 1g
Price: $120
Updated: 2021/12/16

AK Scientific

Product number: H962
Product name: Dropropizine
Packaging: 5g
Price: $47
Updated: 2021/12/16

AK Scientific

Product number: H962
Product name: Dropropizine
Packaging: 100g
Price: $561
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0014296
Product name: DROPROPIZINE
Purity: 95.00%
Packaging: 1G
Price: $716.1
Updated: 2021/12/16

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Dropropizine Chemical Properties,Usage,Production

Originator

Ribex,Formenti

Uses

antitussive

Uses

Dropropizine is a cough suppressant and central sedative therapeutic agent.

Definition

ChEBI: 3-(4-phenyl-1-piperazinyl)propane-1,2-diol is a member of piperazines.

Manufacturing Process

34 g 1,2-epoxy-3-hydroxypropane (glycide) in 50 ml of water were added to 64.8 g 1-phenylpiperazine in 80 ml of ethanol at the temperature not higher 50°C. The mixture was stood at night, then it was evaporated to dryness in vacuum and the stark product was recrystallized from 100 ml of acetone to give 60 g 1-phenyl-4-(2,3-dihydroxypropyl)piperazine (dropropizine) MP 105°C; BP 205°C/1 mm Hg.

Therapeutic Function

Antitussive

Dropropizine Preparation Products And Raw materials

Raw materials

p-Toluenesulfonic acid 1-Phenylpiperazine Ethanol Acetone Sodium sulfate Toluene 2,2-Dimethyl-1,3-dioxolane-4-methanol Sodium borohydride Chloroform Diethanolamine Tosyl chloride Zinc dichloride Hydrochloric acid D-Mannitol Methanol Sodium periodate 3-Chloro-1,2-propanediol Pyridine Phenylpiperazine

Preparation Products

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Dropropizine Suppliers

Canada 1 China 133 Europe 3 France 1 Germany 2 India 6 Italy 1 South Korea 2 Switzerland 1 Ukraine 1 United Kingdom 2 United States 26 Global 179

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 27322
Advantage: 60

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006608290; 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40241
Advantage: 62

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44751
Advantage: 61

Shijiazhuang Sdyano Fine Chemical Co., Ltd.

Tel: 0311-89250318 031166536426
Fax: 4000311741
Email: master@sjzsdyn.com
Country: China
ProdList: 2882
Advantage: 65

JinYan Chemicals(ShangHai) Co.,Ltd.

Tel: 13817811078
Fax: 86-021-50426522,50426273
Email: sales@jingyan-chemical.com
Country: China
ProdList: 9984
Advantage: 60

Adamas Reagent, Ltd.

Tel: 400-6009262 16621234537
Fax: 021-64823266
Email: zhangsn@titansci.com
Country: China
ProdList: 14113
Advantage: 59

LGM Pharma

Tel: 1-(800)-881-8210
Fax: 615-250-9817
Email: inquiries@lgmpharma.com
Country: United States
ProdList: 2127
Advantage: 70

Chemsky (shanghai) International Co.,Ltd

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 15421
Advantage: 60

Syntechem Co.,Ltd

Tel
Fax: E-Mail Inquiry
Email: info@syntechem.com
Country: China
ProdList: 12990
Advantage: 57

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View Lastest Price from Dropropizine manufacturers

Dideu Industries Group Limited

Product: Dropropizine 17692-31-8
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons
Release date: 2022-02-24

Zhuozhou Wenxi import and Export Co., Ltd

Product: Dropropizine 17692-31-8
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-06-27

Shaanxi Dideu Medichem Co. Ltd

Product: Dropropizine 17692-31-8
Price: US $0.10/KG
Min. Order: 1KG
Purity: 99.0%
Supply Ability: 1000 tons
Release date: 2020-04-28

17692-31-8, DropropizineRelated Search:

PHENYL VALERATE 1-Methoxy-2-propyl acetate Hydroxypropyl methyl cellulose 2-Hydroxypropyl-β-cyclodextrin trans-1-Cinnamylpiperazine Diphenyl ether (R)-(-)-1,2-Propanediol Diprophylline 1-Methoxy-2-propanol Propylene glycol 1,3-Propanediol Poly(propylene glycol) Hydroxypropyl cellulose Hydroxypropyl acrylate PHENYL RESIN (S)-Dropropizine mociprazine Centpropazine

3-(4-phenyl-1-piperazinyl)-2-propanediol

catabex

dipropizine

ditustat

dopropizin

katril

larylin

1,2-PROPANEDIOL, 3-(4-PHENYL-1-PIPERAZINYL)-

3-(4-phenylpiperazin-1-yl)propane-1,2-diol

3-(4-Phenyl-1-piperazinyl)1,2-

ribex

tussilex

(+/-)-DROPROPIZINE

DROPROPIZINE

LABOTEST-BB LT00771927

3-[4-PHENYL-1-PIPERAZINYL]-1,2-PROPANEDIOL

gevotuss

UCB-1967

3-(4-Phenyl-1-piperazinyl)-1，2-pmpanediol

3-(4-phenyl-1-piperazinyl)propane-1,2-diol

UCB-196

rac Dropropizine

Dropropizine ISO 9001：2015 REACH

(+-)-dropropizine

(?-Dropropizine

17692-31-8

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