ChemicalBook > CAS DataBase List > 2-AMINO-4-METHOXY-BENZOIC ACID METHYL ESTER

2-AMINO-4-METHOXY-BENZOIC ACID METHYL ESTER

Product Name
2-AMINO-4-METHOXY-BENZOIC ACID METHYL ESTER
CAS No.
50413-30-4
Chemical Name
2-AMINO-4-METHOXY-BENZOIC ACID METHYL ESTER
Synonyms
METHYL 2-AMINO-4-METHOXYBENZOATE;methyl2-amino-4-methoxylbenzoate;2-amino-4-methoxybenzoate, methyl ester;2-AMINO-4-METHOXY-BENZOIC ACID METHYL ESTER;Benzoic acid, 2-amino-4-methoxy-, methyl ester
CBNumber
CB1195664
Molecular Formula
C9H11NO3
Formula Weight
181.19
MOL File
50413-30-4.mol
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2-AMINO-4-METHOXY-BENZOIC ACID METHYL ESTER Property

Melting point:
116-118 °C
Boiling point:
313.7±22.0 °C(Predicted)
Density 
1.179±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
form 
solid
pka
2.17±0.10(Predicted)
Appearance
Off-white to yellow Solid
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Safety

HS Code 
2922500090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H226Flammable liquid and vapour

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P242Use only non-sparking tools.

P243Take precautionary measures against static discharge.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P370+P378In case of fire: Use … for extinction.

P403+P235Store in a well-ventilated place. Keep cool.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
M328633
Product name
Methyl2-amino-4-methoxybenzoate
Packaging
100mg
Price
$45
Updated
2021/12/16
TRC
Product number
M328633
Product name
Methyl2-amino-4-methoxybenzoate
Packaging
500mg
Price
$65
Updated
2021/12/16
AK Scientific
Product number
J90945
Product name
Methyl2-amino-4-methoxylbenzoate
Packaging
1g
Price
$30
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA51189
Product name
2-Amino-4-methoxy-benzoic acid methyl ester
Packaging
2g
Price
$50
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA51189
Product name
2-Amino-4-methoxy-benzoic acid methyl ester
Packaging
5G
Price
$100
Updated
2021/12/16
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2-AMINO-4-METHOXY-BENZOIC ACID METHYL ESTER Chemical Properties,Usage,Production

Synthesis

4294-95-5

18107-18-1

50413-30-4

(Trimethylmethylsilyl) diazomethane (2.0 M ethyl ether solution, 18.0 mL, 36.0 mmol) was added slowly and dropwise to a 10% methanolic tetrahydrofuran solution (100 mL) of 4-methoxyanthranilic acid (5.0 g, 30.0 mmol) at 0 °C. The reaction mixture was kept stirred at room temperature for 16 h. The reaction was subsequently terminated by addition of glacial acetic acid (0.1 mL). The reaction mixture was concentrated and the residue was partitioned between saturated sodium bicarbonate solution (50 mL) and ethyl acetate (250 mL). The organic layer was separated and washed sequentially with water (50 mL), saturated sodium bicarbonate solution (50 mL) and brine (50 mL), dried over anhydrous sodium sulfate, filtered and concentrated to afford methyl 2-amino-4-methoxybenzoate as an oil (5.4 g, quantitative). Mass spectrometry (EI) analysis showed a molecular ion peak (MH+) of 182 for C9H11NO3.

References

[1] Patent: WO2010/135524, 2010, A1. Location in patent: Page/Page column 219
[2] Patent: WO2013/25958, 2013, A1. Location in patent: Page/Page column 69; 70
[3] Patent: WO2014/43446, 2014, A1. Location in patent: Page/Page column 31
[4] Patent: EP2744501, 2016, B1. Location in patent: Paragraph 0204; 0205
[5] Journal of Medicinal Chemistry, 2012, vol. 55, # 7, p. 3170 - 3181

2-AMINO-4-METHOXY-BENZOIC ACID METHYL ESTER Preparation Products And Raw materials

Raw materials

Preparation Products

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2-AMINO-4-METHOXY-BENZOIC ACID METHYL ESTER Suppliers

Energy Chemical
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021-021-58432009 400-005-6266
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sales8178@energy-chemical.com
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China
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Carbott PharmTech Inc.
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shanghai science Bio-Pharmceutical.co,ltd.
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Jia Xing Isenchem Co.,Ltd
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Beijing Eternalchem Co,. Ltd.
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skychemical Co.Ltd
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Wuhan TCASChem Technology Co., Ltd.
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027-86697669 13986148687
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86-027-86697669
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China
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View Lastest Price from 2-AMINO-4-METHOXY-BENZOIC ACID METHYL ESTER manufacturers

Career Henan Chemical Co
Product
2-AMINO-4-METHOXY-BENZOIC ACID METHYL ESTER 50413-30-4
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
200kg
Release date
2019-12-30