esperamicin A1
- Product Name
- esperamicin A1
- CAS No.
- 99674-26-7
- Chemical Name
- esperamicin A1
- Synonyms
- speramicin;esperamicin A1;Eesperamicin A1;Esperamicin A1 (BMY 28175);Carbamic acid, N-[(1R,4Z,8S,12S,13E)-8-[[4,6-dideoxy-2-O-[2,4-dideoxy-3-O-methyl-4-[(1-methylethyl)amino]-α-L-threo-pentopyranosyl]-4-[[(2,6-dideoxy-4-S-methyl-4-thio-β-D-ribo-hexopyranosyl)oxy]amino]-β-D-glucopyranosyl]oxy]-12-[[2,6-dideoxy-3-O-[4,5-dimethoxy-2-[(2-methoxy-1-oxo-2-propen-1-yl)amino...
- CBNumber
- CB21371312
- Molecular Formula
- C59H80N4O22S4
- Formula Weight
- 1325.54
- MOL File
- 99674-26-7.mol
esperamicin A1 Property
- Density
- 1.43±0.1 g/cm3(Predicted)
- pka
- 6.67±0.70(Predicted)
- CAS DataBase Reference
- 99674-26-7
N-Bromosuccinimide Price
- Product number
- API0011364
- Product name
- ESPERAMICIN A1
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $495.78
- Updated
- 2021/12/16
esperamicin A1 Chemical Properties,Usage,Production
Uses
Esperamicin A1, as an extremely potent antitumor antibiotic, is isolated from cultures of Actinomadura verrucosospora. Esperamicin A1 can be used for the research of antitumor[1]. Eesperamicin A1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Definition
ChEBI: A naturally occurring antibiotic and antitumor agent isolated from Actinomadura verrucosopora. Its chemical structure consists of a core bicyclo[7.3.1]tridecadiynene moiety containing a 1,5-diyn-3-ene as part of a ten-membered ring, a lpha,beta-unsaturated ketone with a bridgehead double bond and an attached allylic trisulfide. This ring system is attached at one end by a trisaccharide moiety and at the opposite end by a 2-deoxy-L-fucose-anthra ilate moiety. The trisaccharide consists of a hydroxyamino sugar which is connected to a isopropylamino sugar through a glycosidic linkage and a thiomethyl sugar through an NH1O linkage.
References
[1] Lam, K. S., et al. Biosynthesis of esperamicin A1, an enediyne antitumor antibiotic. Journal of the American Chemical Society, 115(26), 12340–12345.
esperamicin A1 Preparation Products And Raw materials
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