Methyl 2-amino-4,5-dimethoxybenzoate

Product Name: Methyl 2-amino-4,5-dimethoxybenzoate
CAS No.: 26759-46-6
Chemical Name: Methyl 2-amino-4,5-dimethoxybenzoate
Synonyms: METHYL 6-AMINOVERATRATE;Methyl 2-aMino-4;TIMTEC-BB SBB008554;5-diMethoxy benzoate;LABOTEST-BB LT00454153;Gefitinib interMediate I;METHYL 4,5-DIMETHOXYANTHRANILATE;6-AMINOVERATRIC ACID METHYL ESTER;Methyl4,5-Dimethoxyanthranilate>2-amino-4,5-dimethoxy-benzate ester
CBNumber: CB8153869
Molecular Formula: C10H13NO4
Formula Weight: 211.21
MOL File: 26759-46-6.mol

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Methyl 2-amino-4,5-dimethoxybenzoate Property

Melting point:: 128-133 °C
Boiling point:: 343.1±37.0 °C(Predicted)
Density: 1.189±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
form: powder to crystal
pka: 2.68±0.10(Predicted)
color: White to Light yellow to Light orange
BRN: 2724754
InChI: InChI=1S/C10H13NO4/c1-13-8-4-6(10(12)15-3)7(11)5-9(8)14-2/h4-5H,11H2,1-3H3
InChIKey: QQFHCCQSCQBKBG-UHFFFAOYSA-N
SMILES: C(OC)(=O)C1=CC(OC)=C(OC)C=C1N
CAS DataBase Reference: 26759-46-6(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36-24/25-22
WGK Germany: 3
HazardClass: IRRITANT
HS Code: 29225090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 07725
Product name: Methyl 2-amino-4,5-dimethoxybenzoate
Purity: ≥98.0% (HPLC/NT)
Packaging: 25g
Price: $61.3
Updated: 2023/06/20

TCI Chemical

Product number: D2749
Product name: Methyl 4,5-Dimethoxyanthranilate
Purity: >98.0%(GC)(T)
Packaging: 25g
Price: $45
Updated: 2025/07/31

Usbiological

Product number: 454818
Product name: Methyl 2-amino-4,5-dimethoxybenzoate
Packaging: 500mg
Price: $305
Updated: 2021/12/16

Usbiological

Product number: 454789
Product name: Methyl 2-amino-4-
Packaging: 100mg
Price: $305
Updated: 2021/12/16

Usbiological

Product number: 454796
Product name: Methyl 2-amino-4-
Packaging: 100mg
Price: $319
Updated: 2021/12/16

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Methyl 2-amino-4,5-dimethoxybenzoate Chemical Properties,Usage,Production

Chemical Properties

Brown crystalline powder

Uses

3-Acetamido-2-hydroxyacetophenone is used in the preparation fo Antitumor Agents in Breast Cancer.

reaction suitability

reaction type: solution phase peptide synthesis

Synthesis

26791-93-5

26759-46-6

General procedure for the synthesis of methyl 2-amino-4,5-dimethoxybenzoate from methyl 4,5-dimethoxy-2-nitrobenzoate: 1.9 g (7.2 mmol) of methyl 4,5-dimethoxy-2-nitrobenzoate and 0.2 g of palladium-carbon catalyst were added to a 100 mL round-bottomed flask and dissolved in 50 mL of methanol. Hydrogen was passed into the reaction system and the reaction mixture was stirred at room temperature for 24 hours. The reaction progress was monitored by thin layer chromatography (TLC). Upon completion of the reaction, the brown solid catalyst was removed by filtration. The product was separated and purified by column chromatography (eluent ratio: petroleum ether:ethyl acetate = 10:1, V/V) to afford 1.51 g of the white solid target compound in 88.7% yield with a melting point of 91-93°C. The product was purified by column chromatography (eluent ratio: petroleum ether:ethyl acetate = 10:1, V/V).

References

[1] Patent: CN105037279, 2017, B. Location in patent: Paragraph 0047; 0048
[2] Bioorganic and Medicinal Chemistry Letters, 2014, vol. 24, # 18, p. 4455 - 4459
[3] Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1995, vol. 34, # 10, p. 911 - 913
[4] Justus Liebigs Annalen der Chemie, 1896, vol. 293, p. 190
[5] Journal of the American Chemical Society, 1919, vol. 41, p. 2147

Methyl 2-amino-4,5-dimethoxybenzoate Preparation Products And Raw materials

Raw materials

Preparation Products

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Methyl 2-amino-4,5-dimethoxybenzoate Suppliers

Americas 1 Belgium 2 China 152 Europe 3 France 1 Germany 5 India 17 Japan 2 Slovakia 1 South Korea 1 Switzerland 3 Ukraine 2 United Kingdom 15 United States 32 Global 237

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View Lastest Price from Methyl 2-amino-4,5-dimethoxybenzoate manufacturers

Zibo Shiji Zhonglian Medical Technology Co., Ltd.

Product: Methyl 2-amino-4,5-dimethoxybenzoate 26759-46-6
Price: US $0.00/KG
Min. Order: 25KG
Purity: 99.8%
Supply Ability: 2000KG/th
Release date: 2023-02-09

Zhuozhou Wenxi import and Export Co., Ltd

Product: Methyl 2-amino-4,5-dimethoxybenzoate 26759-46-6
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-11

Zhuozhou Wenxi import and Export Co., Ltd

Product: Methyl 2-amino-4,5-dimethoxybenzoate 26759-46-6
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-09

26759-46-6, Methyl 2-amino-4,5-dimethoxybenzoateRelated Search:

Methyl acrylate Acetonitrile 3,5-Dimethoxybenzoic acid 4-Methoxybenzoic acid Kresoxim-methyl Methylparaben Methyl anthranilate Basic Violet 1 4-Dimethylaminobenzoic acid Methyl benzoate 4-Aminobenzoic acid Paraquat dichloride Methanol Methyl acetate Glycine Methyl Anthranilic acid ETHYL 4,5-DIMETHOXY-2-NITROBENZOATE

2-AMINO-4,5-DIMETHOXYBENZOIC ACID METHYL ESTER

2-AMINO-4,5-DIMETHOXY METHYL BENZOATE

4,5-DIMETHOXYANTHRANILIC ACID METHYL

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METHYL 6-AMINO-3,4-DIMETHOXYBENZOATE

METHYL 6-AMINOVERATRATE

METHYL 4,5-DIMETHOXYANTHRANILATE

2-Amino-4,5-Dimethoxy Benzoate de methyl

3,4-Dimethoxy-6-Aminomethyl Benzoate

METHYL 2-AMINO-4,5-DIMETHOXYBENZOATE

LABOTEST-BB LT00454153

TIMTEC-BB SBB008554

2-amino-4,5-dimethoxy-benzate ester

6-AMINO-3,4-DIMETHOXYBENZOIC ACID METHYL ESTER

4,5-DIMETHOXY-2-AMINOBENZOIC ACID METHYL ESTER

3,4-DIMETHOXY-6-AMINOBENZOICACIDMETHYLESTER

Benzoicacid,2-amino-4,5-dimethoxy-methylester

Methyl 4,5-dimethoxyanthranilate, Methyl 6-aminoveratrate

5-diMethoxy benzoate

Methyl 2-aMino-4

Gefitinib interMediate I

2-Amino-4,5-dimethoxybenzoic Acid Methyl Ester 6-Aminoveratric Acid Methyl Ester 4,5-Dimethoxyanthranilic Acid Methyl Ester Methyl 2-Amino-4,5-dimethoxybenzoate Methyl 6-Aminoveratrate

3'-AcetaMido-2'-hydroxyacetophenone

Methyl4,5-Dimethoxyanthranilate&gt

Benzoic acid, 2-amino-4,5-dimethoxy-, methyl ester (9CI, ACI)

2-amino-4,5-dimethoxy-Benzoic acid methyl ester (9CI ACI)

26759-46-6

C10H13NO4

Unnatural Amino Acid Derivatives

Peptide Synthesis

Specialty Synthesis

Aromatic Amino Acids

FINE Chemical & INTERMEDIATES

Aromatic Esters

Organic acids