ChemicalBook > CAS DataBase List > 1-Methylindole-3-carboxaldehyde

1-Methylindole-3-carboxaldehyde

Product Name
1-Methylindole-3-carboxaldehyde
CAS No.
19012-03-4
Chemical Name
1-Methylindole-3-carboxaldehyde
Synonyms
1-METHYL-1H-INDOLE-3-CARBALDEHYDE;3-formyl-1-methylindole;NSC 83042;AKOS JY2082515;RARECHEM AH BS 0121;TIMTEC-BB SBB010057;N-Methyl-3-formylindole;ASINEX-REAG BAS 12967420;N-methyl-3-carboxaldehyde;1 METHYLINDOLE-3-ALDEHYDE
CBNumber
CB1201057
Molecular Formula
C10H9NO
Formula Weight
159.18
MOL File
19012-03-4.mol
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1-Methylindole-3-carboxaldehyde Property

Melting point:
70-72 °C (lit.)
Boiling point:
186-189 °C(Press: 3-4 Torr)
Density 
1.10±0.1 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
form 
Crystalline Powder and Chunks
color 
Light yellow to orange or brown
Water Solubility 
Insoluble in water.
Sensitive 
Air Sensitive
BRN 
121302
CAS DataBase Reference
19012-03-4(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-37/39
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
29339900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
357987
Product name
1-Methylindole-3-carboxaldehyde
Purity
97%
Packaging
5g
Price
$85.2
Updated
2024/03/01
Sigma-Aldrich
Product number
357987
Product name
1-Methylindole-3-carboxaldehyde
Purity
97%
Packaging
25g
Price
$515
Updated
2023/06/20
Alfa Aesar
Product number
L02212
Product name
1-Methylindole-3-carboxaldehyde, 98+%
Packaging
1g
Price
$31.65
Updated
2024/03/01
Alfa Aesar
Product number
L02212
Product name
1-Methylindole-3-carboxaldehyde, 98+%
Packaging
5g
Price
$80.65
Updated
2024/03/01
SynQuest Laboratories
Product number
4H15-1-0J
Product name
1-Methyl-1H-indole-3-carboxaldehyde
Purity
98%
Packaging
5G
Price
$80
Updated
2021/12/16
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1-Methylindole-3-carboxaldehyde Chemical Properties,Usage,Production

Chemical Properties

light yellow to orange or brown crystalline powder

Uses

Reactant for preparation of nitroolefins and β-nitroalcohols via microwave- or ultrasound-assisted Henry reactions Reactant for synthesis of quinolinones via three-component Ugi reaction Reactant for synthesis of α-ketoamides as inhibitors of Dengue virus protease with antiviral activity in cell-culture Reactant for preparation of thiazolopyrimidinones as inhibitors of Bcl-2 proteins Reactant for preparation of vinylindoles via Peterson olefination or olefination with Nysted reagent Reactant for preparation of indolyl alkenes from microwave-enhanced Knoevenagel condensation as antibacterial agents.

Uses

1-Methylindole-3-carboxaldehyde is used as a reactant for preparation of nitroolefins and β-nitroalcohols via microwave- or ultrasound-assisted Henry reactions, reactant for synthesis of quinolinones via three-component Ugi reaction, reactant for synthesis of α-ketoamides as inhibitors of Dengue virus protease with antiviral activity in cell-culture, reactant for preparation of thiazolopyrimidinones as inhibitors of Bcl-2 proteins, reactant for preparation of vinylindoles via Peterson olefination or olefination with Nysted reagent, reactant for preparation of indolyl alkenes from microwave-enhanced Knoevenagel condensation as antibacterial agents 1-Methylindole-3-carboxaldehyde may be used in the synthesis of (Z)-3-(1-methyl-1H-indol-3-yl)-2-(thiophen-3-yl)acrylonitrile, via base-catalyzed condensation with thiophene-3-acetonitrile. It was also used in the preparation of monomer, required for the synthesis of poly(3-vinyl-1-methylindole).

Synthesis Reference(s)

Tetrahedron, 49, p. 4015, 1993 DOI: 10.1016/S0040-4020(01)89915-4
Synthesis, p. 396, 1987 DOI: 10.1055/s-1987-27960

General Description

1-Methylindole-3-carboxaldehyde is a heterocyclic indole aldehyde. 1-Methylindole-3-carboxaldehyde on condensation with 2-hydroxybenzohydrazide yields Schiff base.

1-Methylindole-3-carboxaldehyde Preparation Products And Raw materials

Raw materials

Preparation Products

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1-Methylindole-3-carboxaldehyde Suppliers

J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
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jkinfo@jkchemical.com
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China
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96815
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Meryer (Shanghai) Chemical Technology Co., Ltd.
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021-61259108 18621169109
Fax
86-21-61259102
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market03@meryer.com
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China
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INTATRADE GmbH
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+49 3493/605464
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+49 3493/605470
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sales@intatrade.de
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Germany
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Alfa Aesar
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400-6106006
Fax
021-67582001/03/05
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saleschina@alfa-asia.com
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China
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Energy Chemical
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Capot Chemical Co., Ltd
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Beijing Ouhe Technology Co., Ltd
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+86-10-82967029
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China
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Jia Xing Isenchem Co.,Ltd
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0573-85285100 18627885956
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0573-85285100
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isenchem@163.com
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China
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Accela ChemBio Co.,Ltd.
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021-50795510 4000665055
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021-50795055
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sales@accelachem.com
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China
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Nanjing Chemlin Chemical Co., Ltd
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025-83697070
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+86-25-83453306
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info@chemlin.com.cn
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China
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View Lastest Price from 1-Methylindole-3-carboxaldehyde manufacturers

Hebei Mojin Biotechnology Co., Ltd
Product
1-Methylindole-3-carboxaldehyde 19012-03-4
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2024-01-29
Henan Xiangtong Chemical Co., Ltd.
Product
1-Methylindole-3-carboxaldehyde 19012-03-4
Price
US $1.00/KG
Min. Order
1KG
Purity
99
Supply Ability
100T
Release date
2019-08-02
Zhuozhou Wenxi import and Export Co., Ltd
Product
1-Methylindole-3-carboxaldehyde 19012-03-4
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-08-11

19012-03-4, 1-Methylindole-3-carboxaldehydeRelated Search:


  • TIMTEC-BB SBB010057
  • RARECHEM AH BS 0121
  • 1 METHYLINDOLE-3-ALDEHYDE
  • 1-METHYLINDOLE-3-CARBALDEHYDE
  • 1-METHYLINDOLE-3-CARBOXALDEHYDE
  • 1-METHYL-1H-INDOLE-3-CARBALDEHYDE
  • 1-METHYL-1H-INDOLE-3-CARBOXALDEHYDE
  • AKOS JY2082515
  • N-Methylindole-3-Carboxaldehyde
  • N-methyl-3-carboxaldehyde
  • ASINEX-REAG BAS 12967420
  • 1H-Indole-3-carboxaldehyde, 1-methyl- (9CI)
  • 3-formyl-1-methylindole
  • 1-METHYLINDOLE-3-CARBOXALDEHYDE 98% (HPLC)
  • 1-Methylindole-3-carboxaldehyde, 98+%
  • 3-Formyl-1-methyl-1H-indole
  • 1-METHYLINDOLE-3-CARBOXALDEHYDE (1MeIAld)
  • 1-Methylindole-3-carboxaldehyde,97%
  • 1-methyl-1H-indole-3-carbaldehyde(SALTDATA: FREE)
  • 1-Methylindole-3-carboxaldehyde, 97% 1GR
  • 1-Methyl-3- Indole Carboxaldehyde
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  • N-Methyl-3-formylindole
  • N-Methylindole-3-aldehyde
  • NSC 83042
  • 1-Methylindole-3-carboxaldehyde 97%
  • 1H-Indole-3-carboxaldehyde, 1-Methyl-
  • Methylindole-3-carboxaldeh
  • 1-Methylndole-3-carboxaldehyde
  • 1-Methylindole-3-carboxaldehyde ISO 9001:2015 REACH
  • 1-Methyl-1H-indol-3-carbaldehyde
  • 19012-03-4
  • 18012-03-4
  • ALDEHYDE
  • Building Blocks
  • Heterocyclic Building Blocks
  • Indoles
  • Heterocycle-Indole series
  • Heterocycles
  • Building Blocks
  • Heterocyclic Building Blocks
  • Indoles
  • Indoles and derivatives
  • Indole
  • Heterocyclic Compounds
  • ALDEHYDE