ETHYL [BIS(2,2,2-TRIFLUOROETHOXY)PHOSPHINYL]ACETATE
- Product Name
- ETHYL [BIS(2,2,2-TRIFLUOROETHOXY)PHOSPHINYL]ACETATE
- CAS No.
- 124755-24-4
- Chemical Name
- ETHYL [BIS(2,2,2-TRIFLUOROETHOXY)PHOSPHINYL]ACETATE
- Synonyms
- ETHYL [BIS(2,2,2-TRIFLUOROETHOXY)PHOSPHINYL]ACETATE;Ethyl 2-[bis(2,2,2-trifluoroethoxy)phosphinyl]acetate;Ethyl 2-(bis(2,2,2-trifluoroethoxy)phosphoryl)acetate;Ethyl [bis(2,2,2-trifluoroethoxy)phosphinyl]acetate 97%;Di(3,3,3-trifluoroethyl)(ethoxycarbonylmethyl)phosphonate;[Bis-(2,2,2-trifluoro-ethoxy)-phosphoryl]-acetic acid ethyl ester;[BIS-(2,2,2-TRIFLUORO-ETHOXY)-PHOSPHORYL]-ACETIC ACID METHYL ESTER;Acetic acid, 2-[bis(2,2,2-trifluoroethoxy)phosphinyl]-, ethyl ester
- CBNumber
- CB1206274
- Molecular Formula
- C8H11F6O5P
- Formula Weight
- 332.13
- MOL File
- 124755-24-4.mol
ETHYL [BIS(2,2,2-TRIFLUOROETHOXY)PHOSPHINYL]ACETATE Property
- Boiling point:
- 249-250 °C(lit.)
- Density
- 1.403 g/mL at 25 °C(lit.)
- refractive index
- n20/D 1.3730(lit.)
- Flash point:
- >230 °F
- InChIKey
- HBYHPBCAZBLFTD-UHFFFAOYSA-N
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- E677510
- Product name
- Ethyl[Bis(2,2,2-trifluoroethoxy)phosphinyl]acetate
- Packaging
- 1g
- Price
- $100
- Updated
- 2021/12/16
- Product number
- P000231421
- Product name
- Ethyl 2-(bis(2,2,2-trifluoroethoxy)phosphoryl)acetate
- Purity
- 97%
- Packaging
- 5g
- Price
- $102
- Updated
- 2021/12/16
- Product number
- Z4021
- Product name
- Ethyl2-(bis(2,2,2-trifluoroethoxy)phosphoryl)acetate
- Packaging
- 5g
- Price
- $237
- Updated
- 2021/12/16
- Product number
- P000231421
- Product name
- Ethyl 2-(bis(2,2,2-trifluoroethoxy)phosphoryl)acetate
- Purity
- 97%
- Packaging
- 25g
- Price
- $403
- Updated
- 2021/12/16
- Product number
- P000231421
- Product name
- Ethyl 2-(bis(2,2,2-trifluoroethoxy)phosphoryl)acetate
- Purity
- 97%
- Packaging
- 10g
- Price
- $170
- Updated
- 2021/12/16
ETHYL [BIS(2,2,2-TRIFLUOROETHOXY)PHOSPHINYL]ACETATE Chemical Properties,Usage,Production
Uses
Ethyl [Bis(2,2,2-trifluoroethoxy)phosphinyl]acetate is a reagent used in the preparation of spiroketal EBC-23; an anticancer agent, scytonemin A; a novel calcium antagonist and other useful organic compounds.
Synthesis
To stirred solution of 18-crown-6 (4.40 g, 16.65 mmol), THF (20 mL), and bis (2,2,2-trifluoroethyl) phosphite (1) (0.55 mL, 3.75 mmol), KHMDS (8.0 mL, 4.00 mmol, 0.5 M in toluene) was added via syringe in a dropwise manner at -78 oC. Ethyl chloroacetate (0.35 mL, 3.30 mmol) was added to the flask after 15 min. The reaction flask was allowed to warm to room temperature and stir for 4 hr. After standard workup procedure, the crude product was then purified by flash column chromatography (2:1-1:1 hexanes:EtOAc, Rf = 0.25 in 2:1 hexanes:EtOAc) yielding Ethyl [bis(2,2,2-trifluoroethoxy)phosphinyl]acetate (808 mg, 2.43 mmol, 73.4%) as a yellow syrup.
ETHYL [BIS(2,2,2-TRIFLUOROETHOXY)PHOSPHINYL]ACETATE Preparation Products And Raw materials
Raw materials
Preparation Products
ETHYL [BIS(2,2,2-TRIFLUOROETHOXY)PHOSPHINYL]ACETATE Suppliers
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View Lastest Price from ETHYL [BIS(2,2,2-TRIFLUOROETHOXY)PHOSPHINYL]ACETATE manufacturers
- Product
- Ethyl 2-(bis(2,2,2-trifluoroethoxy)phosphoryl)acetate 124755-24-4
- Price
- US $1.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 50 tons
- Release date
- 2020-01-17