4-[2-(Dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]-phenol hydrochloride

Product Name: 4-[2-(Dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]-phenol hydrochloride
CAS No.: 300827-87-6
Chemical Name: 4-[2-(Dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]-phenol hydrochloride
Synonyms: D2069;Desvenlafaxine HCl;Venlafaxine Impurity 16;Desvenlafaxine hydrochloride;4-[2-(Dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]-phenol hydrochloride
CBNumber: CB12101937
Molecular Formula: C16H25NO2HCl
Formula Weight: 0
MOL File: 300827-87-6.mol

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4-[2-(Dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]-phenol hydrochloride Property

Melting point:: >75°C (dec.)
storage temp.: 2-8°C
solubility: DMSO: >20mg/mL
form: powder
color: white to off-white
Stability:: Hygroscopic

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Safety

Hazard Codes: Xn
Risk Statements: 22-36
Safety Statements: 26
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Warning
Hazard statements: H319Causes serious eye irritation
Precautionary statements: P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: D2069
Product name: Desvenlafaxine hydrochloride
Purity: ≥98% (HPLC), powder
Packaging: 10mg
Price: $233
Updated: 2024/03/01

Sigma-Aldrich

Product number: D2069
Product name: Desvenlafaxine hydrochloride
Purity: ≥98% (HPLC), powder
Packaging: 50mg
Price: $711
Updated: 2024/03/01

TRC

Product number: D297928
Product name: Desvenlafaxine hydrochloride
Packaging: 50mg
Price: $525
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0008432
Product name: DESVENLAFAXINE HYDROCHLORIDE
Purity: 95.00%
Packaging: 10MG
Price: $713.71
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0008432
Product name: DESVENLAFAXINE HYDROCHLORIDE
Purity: 95.00%
Packaging: 50MG
Price: $1220.03
Updated: 2021/12/16

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4-[2-(Dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]-phenol hydrochloride Chemical Properties,Usage,Production

Uses

Desvenlafaxine Hydrochloride is a major active metabolite of venlafaxine (V120000), which is a slective serotonin noradrenaline reuptake inhibitor and used as an antidepressant.

Uses

Desvenlafaxine hydrochloride has been used to evaluate if its occurrence in drinking water at environmental concentrations could induce neuronal gene expression.

Biochem/physiol Actions

Desvenlafaxine hydrochloride is a dual SERT/NET reuptake inhibitor. It is a major active metabolite of venlafaxine (#542); brain penetrant; Ki = 40 nM and 122 nM for hSERT and hNET, respectively (weak binding at the hDAT). Inhibition of [3H]5-HT or [3H]NE uptake for the hSERT or hNET produced IC50 values of 47 and 531 nM.

4-[2-(Dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]-phenol hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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4-[2-(Dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]-phenol hydrochloride Suppliers

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300827-87-6, 4-[2-(Dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]-phenol hydrochlorideRelated Search:

1-[2-(DiMethyloxidoaMino)-1-(4-Methoxyphenyl)ethyl]cyclohexanol rac N-DesMethyl-N-(4-Methoxyphenethyl) Venlafaxine 2-(1-HydroxyCyclohexyl)-2-(4-MethoxyPhenyl)Acetonitrile 1-[2-Amino-1-(4-methoxyphenyl)-ethyl]-cyclohexanol hydrochloride ethyl 3-(dimethylamino)-2-(4-methoxyphenyl)propanoate hydrochloride Venlafaxine N-Dimer (5RS)-5-(4-Methoxyphenyl)-3-Methyl-1-oxa-3-azaspiro-[5.5]undecane Hydrochloride Venlafaxine Related Compound A (10 mg) (1-(1-(4-Methoxyphenyl)-2-(methylamino)ethyl)cyclohexanol hydrochloride) D,L-N,N-Didesmethyl-N-(4-methoxyphenethyl) Venlafaxine (2RS)-2-(Cyclohex-1-enyl)-2-(4-Methoxyphenyl)-N,N-diMethylethanaMine Hydrochloride (2RS)-2-Cyclohexyl-2-(4-Methoxyphenyl)-N,NdiMethylethanaMineHydrochloride Venlafaxine hydrochloride

4-[2-(Dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]-phenol hydrochloride

Desvenlafaxine hydrochloride

D2069

Venlafaxine Impurity 16

Desvenlafaxine HCl

300827-87-6