8-OH-DPAT·hydrobromide
- Product Name
- 8-OH-DPAT·hydrobromide
- CAS No.
- 76135-31-4
- Chemical Name
- 8-OH-DPAT·hydrobromide
- Synonyms
- 8-OH-DPAT HRr;Serotonin agonist DPAT;Benzene,1,3,7-trimethoxy-;Hydroxy-DPAT hydrobromide, 8-;3-(Dipropylamino)tetralin-5-ol·hydrobrominate;Propanoicacid,3-bromo-,1,5-dimethylethylester;(±)-7-Hydroxy-2-dipropylaMinotetralinhydrobroMide;rac-8-Hydroxy-2-dipropylaMinotetralin HydrobroMide;8-Hydroxy-DPAT hydrobromide, 5-HT1a receptor agonist;2-Propenoicacid,2-methyl-,2-(7-hydroxyethoxy)ethylester
- CBNumber
- CB12271735
- Molecular Formula
- C16H25NO.BrH
- Formula Weight
- 328.29
- MOL File
- 76135-31-4.mol
8-OH-DPAT·hydrobromide Property
- Melting point:
- 221.5-222.0 °C
- storage temp.
- Desiccate at +4°C
- solubility
- Soluble to 20 mM in water with gentle warming
- form
- Powder
- color
- White to off-white
- EPA Substance Registry System
- 1-Naphthalenol, 7-(dipropylamino)-5,6,7,8-tetrahydro-, hydrobromide (1:1) (76135-31-4)
Safety
- HS Code
- 2921199990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P271Use only outdoors or in a well-ventilated area.
N-Bromosuccinimide Price
- Product number
- 22608
- Product name
- 8-hydroxy DPAT (hydrobromide)
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $49
- Updated
- 2024/03/01
- Product number
- 22608
- Product name
- 8-hydroxy DPAT (hydrobromide)
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $73
- Updated
- 2024/03/01
- Product number
- 22608
- Product name
- 8-hydroxy DPAT (hydrobromide)
- Purity
- ≥98%
- Packaging
- 25mg
- Price
- $168
- Updated
- 2024/03/01
- Product number
- H941450
- Product name
- rac-8-Hydroxy-2-dipropylaminotetralinHydrobromide
- Packaging
- 10mg
- Price
- $165
- Updated
- 2021/12/16
- Product number
- B6337
- Product name
- 8-Hydroxy-DPAThydrobromide
- Packaging
- 10mg
- Price
- $71
- Updated
- 2021/12/16
8-OH-DPAT·hydrobromide Chemical Properties,Usage,Production
Uses
Dopamine receptor Agonist.
Biological Activity
The standard selective 5-HT1A agonist. Also has moderate affinity for 5-HT7 receptors (pKi is 6.6 at the human 5-HT7 receptor expressed in HEK 293 cells). Reduces hippocampal 5-HT levels following systemic administration in rats in vivo.
in vivo
8-OH-DPAT (8-Hydroxy-DPAT) hydrobromide (32, 56, 80, 100 mg/kg; intramuscularly; 15 min prior to the testing session) of the highest dose significantly interferes with sustained attention and reinforcer efficacy (progressive ratio; PR) performance in the 3,4-methylenedioxymethamphetamine (MDMA)-exposed but not control animals[1].
IC 50
5-HT1A Receptor: 8.19 (pIC50)
storage
Desiccate at +4°C
8-OH-DPAT·hydrobromide Preparation Products And Raw materials
Raw materials
Preparation Products
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