ChemicalBook > CAS DataBase List > 8-OH-DPAT·hydrobromide

8-OH-DPAT·hydrobromide

Product Name: 8-OH-DPAT·hydrobromide
CAS No.: 76135-31-4
Chemical Name: 8-OH-DPAT·hydrobromide
Synonyms: 8-OH-DPAT HRr;Serotonin agonist DPAT;Benzene,1,3,7-trimethoxy-;Hydroxy-DPAT hydrobromide, 8-;3-(Dipropylamino)tetralin-5-ol·hydrobrominate;Propanoicacid,3-bromo-,1,5-dimethylethylester;(±)-7-Hydroxy-2-dipropylaMinotetralinhydrobroMide;rac-8-Hydroxy-2-dipropylaMinotetralin HydrobroMide;8-Hydroxy-DPAT hydrobromide, 5-HT1a receptor agonist;2-Propenoicacid,2-methyl-,2-(7-hydroxyethoxy)ethylester
CBNumber: CB12271735
Molecular Formula: C16H25NO.BrH
Formula Weight: 328.29
MOL File: 76135-31-4.mol

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8-OH-DPAT·hydrobromide Property

Melting point:: 221.5-222.0 °C
storage temp.: Desiccate at +4°C
solubility: Soluble to 20 mM in water with gentle warming
form: Powder
color: White to off-white
EPA Substance Registry System: 1-Naphthalenol, 7-(dipropylamino)-5,6,7,8-tetrahydro-, hydrobromide (1:1) (76135-31-4)

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Safety

HS Code: 2921199990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 22608
Product name: 8-hydroxy DPAT (hydrobromide)
Purity: ≥98%
Packaging: 5mg
Price: $49
Updated: 2024/03/01

Cayman Chemical

Product number: 22608
Product name: 8-hydroxy DPAT (hydrobromide)
Purity: ≥98%
Packaging: 10mg
Price: $73
Updated: 2024/03/01

Cayman Chemical

Product number: 22608
Product name: 8-hydroxy DPAT (hydrobromide)
Purity: ≥98%
Packaging: 25mg
Price: $168
Updated: 2024/03/01

TRC

Product number: H941450
Product name: rac-8-Hydroxy-2-dipropylaminotetralinHydrobromide
Packaging: 10mg
Price: $165
Updated: 2021/12/16

ApexBio Technology

Product number: B6337
Product name: 8-Hydroxy-DPAThydrobromide
Packaging: 10mg
Price: $71
Updated: 2021/12/16

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8-OH-DPAT·hydrobromide Chemical Properties,Usage,Production

Uses

Dopamine receptor Agonist.

Biological Activity

The standard selective 5-HT1A agonist. Also has moderate affinity for 5-HT7 receptors (pKi is 6.6 at the human 5-HT7 receptor expressed in HEK 293 cells). Reduces hippocampal 5-HT levels following systemic administration in rats in vivo.

in vivo

8-OH-DPAT (8-Hydroxy-DPAT) hydrobromide (32, 56, 80, 100 mg/kg; intramuscularly; 15 min prior to the testing session) of the highest dose significantly interferes with sustained attention and reinforcer efficacy (progressive ratio; PR) performance in the 3,4-methylenedioxymethamphetamine (MDMA)-exposed but not control animals^[1].

IC 50

5-HT_1A Receptor: 8.19 (pIC₅₀)

storage

Desiccate at +4°C

8-OH-DPAT·hydrobromide Preparation Products And Raw materials

Raw materials

Preparation Products

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76135-31-4, 8-OH-DPAT·hydrobromideRelated Search:

BIS(3-AMINOPROPYL) ETHER Ortetamine AURORA KA-7111 1,2,3,4-Tetrahydro-N-methyl-2-naphthalenamine O-desmethylmethoxyphenamine 1,2,3,4-TETRAHYDRO-2-NAPHTHYLAMINE 2-(2-aminoethyl)phenol 5,6,7,8-TETRAHYDRO-1-NAPHTHOL (R)-(+)-8-HYDROXY-DPAT HYDROBROMIDE S(-)-8-HYDROXY-DPAT HYDROBROMIDE 2-(2-aminopropyl)phenol 8-OH-DPAT·hydrobromide

3-(Dipropylamino)tetralin-5-ol·hydrobrominate

Serotonin agonist DPAT

rac-8-Hydroxy-2-dipropylaMinotetralin HydrobroMide

(+/-)-8-Hydroxy(N,N-dipropyl-2-aMino)tetralin HydrobroMide

7-(DipropylaMino)-5,6,7,8-tetrahydro-1-naphthalenol HydrobroMide

8-OH-DPAT HRr

7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-ol hydrobromide

7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-ol hydrobromide76135-31-4

1-Naphthalenol, 7-(dipropylamino)-5,6,7,8-tetrahydro-, hydrobromide (1:1)

Hydroxy-DPAT hydrobromide, 8-

2-Propenoicacid,2-methyl-,2-(7-hydroxyethoxy)ethylester

Benzene,1,3,7-trimethoxy-

Propanoicacid,3-bromo-,1,5-dimethylethylester

5-hydroxytryptamine Receptor,inhibit,8 Hydroxy DPAT hydrobromide,5-HT Receptor,Inhibitor,Serotonin Receptor,8HydroxyDPAT hydrobromide

8-Hydroxy-DPAT hydrobromide, 5-HT1a receptor agonist

(±)-7-Hydroxy-2-dipropylaMinotetralinhydrobroMide

76135-31-4

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