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8-OH-DPAT·hydrobromide

Product Name
8-OH-DPAT·hydrobromide
CAS No.
76135-31-4
Chemical Name
8-OH-DPAT·hydrobromide
Synonyms
8-OH-DPAT HRr;Serotonin agonist DPAT;Benzene,1,3,7-trimethoxy-;Hydroxy-DPAT hydrobromide, 8-;3-(Dipropylamino)tetralin-5-ol·hydrobrominate;Propanoicacid,3-bromo-,1,5-dimethylethylester;(±)-7-Hydroxy-2-dipropylaMinotetralinhydrobroMide;rac-8-Hydroxy-2-dipropylaMinotetralin HydrobroMide;8-Hydroxy-DPAT hydrobromide, 5-HT1a receptor agonist;2-Propenoicacid,2-methyl-,2-(7-hydroxyethoxy)ethylester
CBNumber
CB12271735
Molecular Formula
C16H25NO.BrH
Formula Weight
328.29
MOL File
76135-31-4.mol
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8-OH-DPAT·hydrobromide Property

Melting point:
221.5-222.0 °C
storage temp. 
Desiccate at +4°C
solubility 
Soluble to 20 mM in water with gentle warming
form 
Powder
color 
White to off-white
EPA Substance Registry System
1-Naphthalenol, 7-(dipropylamino)-5,6,7,8-tetrahydro-, hydrobromide (1:1) (76135-31-4)
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Safety

HS Code 
2921199990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

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N-Bromosuccinimide Price

Cayman Chemical
Product number
22608
Product name
8-hydroxy DPAT (hydrobromide)
Purity
≥98%
Packaging
5mg
Price
$49
Updated
2024/03/01
Cayman Chemical
Product number
22608
Product name
8-hydroxy DPAT (hydrobromide)
Purity
≥98%
Packaging
10mg
Price
$73
Updated
2024/03/01
Cayman Chemical
Product number
22608
Product name
8-hydroxy DPAT (hydrobromide)
Purity
≥98%
Packaging
25mg
Price
$168
Updated
2024/03/01
TRC
Product number
H941450
Product name
rac-8-Hydroxy-2-dipropylaminotetralinHydrobromide
Packaging
10mg
Price
$165
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
26421
Product name
rac-8-Hydroxy-2-dipropylaminotetralinHydrobromide
Purity
>98%
Packaging
5mg
Price
$860
Updated
2021/12/16
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8-OH-DPAT·hydrobromide Chemical Properties,Usage,Production

Uses

Dopamine receptor Agonist.

Biological Activity

The standard selective 5-HT1A agonist. Also has moderate affinity for 5-HT7 receptors (pKi is 6.6 at the human 5-HT7 receptor expressed in HEK 293 cells). Reduces hippocampal 5-HT levels following systemic administration in rats in vivo.

in vivo

8-OH-DPAT (8-Hydroxy-DPAT) hydrobromide (32, 56, 80, 100 mg/kg; intramuscularly; 15 min prior to the testing session) of the highest dose significantly interferes with sustained attention and reinforcer efficacy (progressive ratio; PR) performance in the 3,4-methylenedioxymethamphetamine (MDMA)-exposed but not control animals[1].

IC 50

5-HT1A Receptor: 8.19 (pIC50)

storage

Desiccate at +4°C

8-OH-DPAT·hydrobromide Preparation Products And Raw materials

Raw materials

Preparation Products

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8-OH-DPAT·hydrobromide Suppliers

Canada 1 China 41 India 2 United Kingdom 2 United States 9 USA 1 Global 56

76135-31-4, 8-OH-DPAT·hydrobromideRelated Search:

BIS(3-AMINOPROPYL) ETHER Ortetamine AURORA KA-7111 1,2,3,4-Tetrahydro-N-methyl-2-naphthalenamine O-desmethylmethoxyphenamine 1,2,3,4-TETRAHYDRO-2-NAPHTHYLAMINE 2-(2-aminoethyl)phenol 5,6,7,8-TETRAHYDRO-1-NAPHTHOL (R)-(+)-8-HYDROXY-DPAT HYDROBROMIDE S(-)-8-HYDROXY-DPAT HYDROBROMIDE 2-(2-aminopropyl)phenol 8-OH-DPAT·hydrobromide

  • 3-(Dipropylamino)tetralin-5-ol·hydrobrominate
  • Serotonin agonist DPAT
  • rac-8-Hydroxy-2-dipropylaMinotetralin HydrobroMide
  • (+/-)-8-Hydroxy(N,N-dipropyl-2-aMino)tetralin HydrobroMide
  • 7-(DipropylaMino)-5,6,7,8-tetrahydro-1-naphthalenol HydrobroMide
  • 8-OH-DPAT HRr
  • 7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-ol hydrobromide
  • 7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-ol hydrobromide76135-31-4
  • 1-Naphthalenol, 7-(dipropylamino)-5,6,7,8-tetrahydro-, hydrobromide (1:1)
  • Hydroxy-DPAT hydrobromide, 8-
  • 2-Propenoicacid,2-methyl-,2-(7-hydroxyethoxy)ethylester
  • Benzene,1,3,7-trimethoxy-
  • Propanoicacid,3-bromo-,1,5-dimethylethylester
  • 5-hydroxytryptamine Receptor,inhibit,8 Hydroxy DPAT hydrobromide,5-HT Receptor,Inhibitor,Serotonin Receptor,8HydroxyDPAT hydrobromide
  • 8-Hydroxy-DPAT hydrobromide, 5-HT1a receptor agonist
  • (±)-7-Hydroxy-2-dipropylaMinotetralinhydrobroMide
  • 76135-31-4
  • Agonist
  • Intermediates & Fine Chemicals
  • Pharmaceuticals