3,5-DICHLOROPYRAZINE-2-CARBOXAMIDE
- Product Name
- 3,5-DICHLOROPYRAZINE-2-CARBOXAMIDE
- CAS No.
- 312736-50-8
- Chemical Name
- 3,5-DICHLOROPYRAZINE-2-CARBOXAMIDE
- Synonyms
- ,5-DICHLOROPYRAZINE-2-CARBOXAMIDE;3,5-Dichloro-2-pyrazinecarboxamide;3,5-DICHLOROPYRAZINE-2-CARBOXAMIDE;2-PyrazinecarboxaMide,3,5-dichloro-
- CBNumber
- CB12453867
- Molecular Formula
- C5H3Cl2N3O
- Formula Weight
- 192
- MOL File
- 312736-50-8.mol
3,5-DICHLOROPYRAZINE-2-CARBOXAMIDE Property
- Boiling point:
- 299.4±40.0 °C(Predicted)
- Density
- 1.620±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- pka
- 12.99±0.50(Predicted)
- Appearance
- White to yellow Solid
Safety
- HS Code
- 2933998090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- D437143
- Product name
- 3,5-Dichloropyrazine-2-carboxamide
- Packaging
- 100mg
- Price
- $65
- Updated
- 2021/12/16
- Product number
- 3337AB
- Product name
- 3,5-Dichloropyrazine-2-carboxamide
- Packaging
- 100mg
- Price
- $74
- Updated
- 2021/12/16
- Product number
- OR930334
- Product name
- 3,5-Dichloropyrazine-2-carboxamide
- Purity
- 98%
- Packaging
- 250mg
- Price
- $120
- Updated
- 2021/12/16
- Product number
- 119964
- Product name
- 3,5-Dichloropyrazine-2-carboxamide
- Purity
- 95+%
- Packaging
- 250mg
- Price
- $180
- Updated
- 2021/12/16
- Product number
- OR930334
- Product name
- 3,5-Dichloropyrazine-2-carboxamide
- Purity
- 98%
- Packaging
- 1g
- Price
- $275
- Updated
- 2021/12/16
3,5-DICHLOROPYRAZINE-2-CARBOXAMIDE Chemical Properties,Usage,Production
Synthesis
4774-14-5
77287-34-4
312736-50-8
The general procedure for the synthesis of 3,5-dichloropyrazine-2-carboxamide from 2,6-dichloropyrazine and the compound (CAS:77287-34-4) was as follows: to a mixed solution containing 2,6-dichloropyrazine (11.0 g, 73.8 mmol) and formamide (58.6 mL, 1,476 mmol) was slowly added dropwise sodium persulfate (17.1 g, 71.7 mmol). The reaction mixture was stirred at 90 °C for 2 hours, followed by continued stirring at room temperature for 12 hours. After completion of the reaction, the reaction mixture was diluted with water and then extracted with isopropanol/chloroform (1:3, v/v) and the organic phase was washed with brine. The organic layer was dried over anhydrous magnesium sulfate, filtered and concentrated under reduced pressure. The residue was purified by column chromatography (eluent: 70% n-hexane/ethyl acetate) to afford 3,5-dichloropyrazine-2-carboxamide (5.06 g, 36% yield) as an oil.
References
[1] Organic Letters, 2013, vol. 15, # 9, p. 2156 - 2159
[2] Patent: WO2016/6975, 2016, A2. Location in patent: Paragraph 457-459
[3] Patent: KR2016/7347, 2016, A. Location in patent: Paragraph 0359; 0360; 0361; 0362
[4] Patent: WO2018/22992, 2018, A1. Location in patent: Paragraph 0723; 0724
[5] Patent: US2018/72743, 2018, A1. Location in patent: Paragraph 1328-1329
3,5-DICHLOROPYRAZINE-2-CARBOXAMIDE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 3,5-DICHLOROPYRAZINE-2-CARBOXAMIDE manufacturers
- Product
- ,5-DICHLOROPYRAZINE-2-CARBOXAMIDE 312736-50-8
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 95-99%
- Supply Ability
- 500kg/month
- Release date
- 2019-08-01