2,6-Dichloropyrazine
- Product Name
- 2,6-Dichloropyrazine
- CAS No.
- 4774-14-5
- Chemical Name
- 2,6-Dichloropyrazine
- Synonyms
- M-Dichloropyrazine;6-Dichloropyrazine;2,6-Dichlor-pyrazin;2,6-CHLORO PYRAZINE;2,6-DICHLOROPYRAZINE;2,6-dichloro-pyrazin;2,6-Dichloropyrazine>Pyrazine, 2,6-dichloro-;2,6-Dichloro-1,4-diazine;2,6-Dichloropyrazine,99%
- CBNumber
- CB3414088
- Molecular Formula
- C4H2Cl2N2
- Formula Weight
- 148.98
- MOL File
- 4774-14-5.mol
2,6-Dichloropyrazine Property
- Melting point:
- 55-58 °C (lit.)
- Boiling point:
- 122 °C / 40mmHg
- Density
- 1.6445 (rough estimate)
- refractive index
- 1.6300 (estimate)
- Flash point:
- >230 °F
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- Soluble in ethanol and methanol.
- form
- Crystals or Crystalline Powder
- pka
- -3.11±0.10(Predicted)
- color
- White to beige
- BRN
- 2439
- LogP
- 1.530
- CAS DataBase Reference
- 4774-14-5(CAS DataBase Reference)
- NIST Chemistry Reference
- 2,6-Dichloropyrazine(4774-14-5)
- EPA Substance Registry System
- 2,6-Dichloropyrazine (4774-14-5)
Safety
- Hazard Codes
- Xi,Xn
- Risk Statements
- 36/37/38-20/21/22
- Safety Statements
- 26-37/39-36/37/39-22-36
- WGK Germany
- 3
- TSCA
- T
- HazardClass
- IRRITANT
- HS Code
- 29339990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 132497
- Product name
- 2,6-Dichloropyrazine
- Purity
- 98%
- Packaging
- 5g
- Price
- $50
- Updated
- 2023/06/20
- Product number
- D1867
- Product name
- 2,6-Dichloropyrazine
- Purity
- >99.0%(GC)
- Packaging
- 5g
- Price
- $28
- Updated
- 2025/07/31
- Product number
- D1867
- Product name
- 2,6-Dichloropyrazine
- Purity
- >99.0%(GC)
- Packaging
- 25g
- Price
- $81
- Updated
- 2025/07/31
- Product number
- 132497
- Product name
- 2,6-Dichloropyrazine
- Purity
- 98%
- Packaging
- 25g
- Price
- $80.25
- Updated
- 2025/07/31
- Product number
- D435825
- Product name
- 2,6-Dichloropyrazine
- Packaging
- 100g
- Price
- $80
- Updated
- 2021/12/16
2,6-Dichloropyrazine Chemical Properties,Usage,Production
Chemical Properties
White Powder
Uses
2,6-Dichloropyrazine is used in the preparation of pyrazine and pyridine compounds as ATR kinase inhibitors. It is also used in the synthesis of oxacalixarenes containing nitrogen heterocycles.
Synthesis
The production method of 2,6-dichloropyrazine comprises the following steps: carrying out ammoniation and cyclization reactions of raw materials comprising methyl chloroacetate, glyoxal and the like to prepare 2-hydroxypyrazine sodium, reacting 2-hydroxypyrazine sodium with phosphorous oxychloride under the catalysis action of N,N-dimethylaminopyridine to prepare 2-chloropyrazine, and chlorinating 2-chloropyrazine by chlorine under the catalysis action of triethylamine with dimethyl formamide as a solvent to prepare 2,6-dichloropyrazine.
2,6-Dichloropyrazine Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2,6-Dichloropyrazine manufacturers
- Product
- 2,6-Dichloropyrazine 4774-14-5
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 100tons
- Release date
- 2025-11-20
- Product
- 2,6-Dichloropyrazine 4774-14-5
- Price
- US $5.00-0.50/KG
- Min. Order
- 1KG
- Purity
- 99% hplc
- Supply Ability
- 500TONS
- Release date
- 2025-05-08
- Product
- 2,6-Dichloropyrazine 4774-14-5
- Price
- US $10.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100 mt
- Release date
- 2024-11-07