METHYL 3,5-DICHLOROPYRAZINE-2-CARBOXYLATE
- Product Name
- METHYL 3,5-DICHLOROPYRAZINE-2-CARBOXYLATE
- CAS No.
- 330786-09-9
- Chemical Name
- METHYL 3,5-DICHLOROPYRAZINE-2-CARBOXYLATE
- Synonyms
- 2-Methoxycarbonyl-3,5-dichloropyrazine;METHYL 3,5-DICHLOROPYRAZINE-2-CARBOXYLATE;Methyl 3,5-dichloro-2-pyrazinecarboxylate;METHYL 3,5-DICHLOROPYRAZINE-2-CARBOXYLATE 98%;3,5-Dichloro-pyrazine-2-carboxylic acid Methyl ester;Pyrazinecarboxylic acid, 3,5-dichloro-, Methyl ester;2-Pyrazinecarboxylic acid, 3,5-dichloro-, methyl ester
- CBNumber
- CB02453264
- Molecular Formula
- C6H4Cl2N2O2
- Formula Weight
- 207.01
- MOL File
- 330786-09-9.mol
METHYL 3,5-DICHLOROPYRAZINE-2-CARBOXYLATE Property
- Boiling point:
- 269.5±35.0 °C(Predicted)
- Density
- 1.503±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- pka
- -5.96±0.10(Predicted)
- Appearance
- White to off-white Solid
- InChI
- InChI=1S/C6H4Cl2N2O2/c1-12-6(11)4-5(8)10-3(7)2-9-4/h2H,1H3
- InChIKey
- VEDWLDKMRDJFNF-UHFFFAOYSA-N
- SMILES
- C1(C(OC)=O)=NC=C(Cl)N=C1Cl
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- M342903
- Product name
- methyl3,5-dichloropyrazine-2-carboxylate
- Packaging
- 100mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- 3770AB
- Product name
- Methyl3,5-dichloropyrazine-2-carboxylate
- Packaging
- 100mg
- Price
- $70
- Updated
- 2021/12/16
- Product number
- HCH0360304
- Product name
- METHYL-3,5-DICHLOROPYRAZINE-2-CARBOXYLATE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $505.4
- Updated
- 2021/12/16
- Product number
- 3770AB
- Product name
- Methyl3,5-dichloropyrazine-2-carboxylate
- Packaging
- 25g
- Price
- $1111
- Updated
- 2021/12/16
- Product number
- 330786099
- Product name
- Methyl3,5-dichloropyrazine-2-carboxylate
- Packaging
- 25g
- Price
- $1419.6
- Updated
- 2021/12/16
METHYL 3,5-DICHLOROPYRAZINE-2-CARBOXYLATE Chemical Properties,Usage,Production
Synthesis
312736-49-5
74-88-4
330786-09-9
At 23 °C, 3,5-dichloropyrazine-2-carboxylic acid (2.68 g, 13.9 mmol) and sodium bicarbonate (1.4 g, 16.6 mmol) were dissolved in DMF (20 mL), followed by addition of iodomethane (5.21 mL, 83 mmol). After completion of the reaction, the reaction mixture was diluted with 10% aqueous citric acid and extracted with EtOAc. The organic layers were combined, washed sequentially with water and brine, dried over anhydrous MgSO4 and concentrated under reduced pressure to afford the brown solid product methyl 3,5-dichloropyrazine-2-carboxylate (2.83 g, 13.6 mmol, 98% yield). The structure of the product was confirmed by 1H NMR (400 MHz, DMSO-d6): δ 3.95 (s, 3H), 8.94 (s, 1H).
References
[1] Patent: WO2009/89042, 2009, A1. Location in patent: Page/Page column 113
[2] Patent: WO2018/81091, 2018, A1. Location in patent: Paragraph 0127; 0128; 0129
[3] Patent: US2014/148454, 2014, A1. Location in patent: Paragraph 0700
[4] Patent: WO2014/82739, 2014, A1. Location in patent: Page/Page column 64
[5] Patent: US2004/142930, 2004, A1
METHYL 3,5-DICHLOROPYRAZINE-2-CARBOXYLATE Preparation Products And Raw materials
Raw materials
Preparation Products
METHYL 3,5-DICHLOROPYRAZINE-2-CARBOXYLATE Suppliers
- Tel
- 0931-4190454 13893344397
- sales@kyxpharma.com
- Country
- China
- ProdList
- 3153
- Advantage
- 58
- Tel
- 021-021-58432009 400-005-6266
- Fax
- 021-58436166
- sales8178@energy-chemical.com
- Country
- China
- ProdList
- 44801
- Advantage
- 61
- Tel
- 0535-6385396
- Fax
- +86 (535) 638-9971
- info@carbottpharm.com
- Country
- China
- ProdList
- 957
- Advantage
- 56
- Tel
- 021-54306202 13764082696
- info@hanhongsci.com
- Country
- China
- ProdList
- 42934
- Advantage
- 64
- Tel
- 0510-83588313-811 18800520310
- sales@chemshuttle.com
- Country
- China
- ProdList
- 2999
- Advantage
- 62
- Tel
- 0931-4190454 13893344397
- Fax
- +86-931-8506154
- sales@kyxpharma.com
- Country
- China
- ProdList
- 310
- Advantage
- 55
- Tel
- 021-58170097
- info@topbiochem.com
- Country
- China
- ProdList
- 9510
- Advantage
- 58
- Tel
- 021-60343070
- Fax
- 021-35122006
- Country
- China
- ProdList
- 12740
- Advantage
- 55
- Tel
- +86-021-50935922
- Fax
- +86-021-33847795
- Country
- China
- ProdList
- 7865
- Advantage
- 55
- Tel
- 400-164-7117 13681763483
- Fax
- +86-21-61629029
- product02@bidepharm.com
- Country
- China
- ProdList
- 39966
- Advantage
- 60