ChemicalBook > CAS DataBase List > 2,6-Dichloropyrazine

2,6-Dichloropyrazine

Product Name
2,6-Dichloropyrazine
CAS No.
4774-14-5
Chemical Name
2,6-Dichloropyrazine
Synonyms
M-Dichloropyrazine;6-Dichloropyrazine;2,6-Dichlor-pyrazin;2,6-CHLORO PYRAZINE;2,6-DICHLOROPYRAZINE;2,6-dichloro-pyrazin;2,6-Dichloropyrazine>Pyrazine, 2,6-dichloro-;2,6-Dichloro-1,4-diazine;2,6-Dichloropyrazine,99%
CBNumber
CB3414088
Molecular Formula
C4H2Cl2N2
Formula Weight
148.98
MOL File
4774-14-5.mol
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2,6-Dichloropyrazine Property

Melting point:
55-58 °C (lit.)
Boiling point:
122 °C / 40mmHg
Density 
1.6445 (rough estimate)
refractive index 
1.6300 (estimate)
Flash point:
>230 °F
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
Soluble in ethanol and methanol.
form 
Crystals or Crystalline Powder
pka
-3.11±0.10(Predicted)
color 
White to beige
BRN 
2439
LogP
1.530
CAS DataBase Reference
4774-14-5(CAS DataBase Reference)
NIST Chemistry Reference
2,6-Dichloropyrazine(4774-14-5)
EPA Substance Registry System
2,6-Dichloropyrazine (4774-14-5)
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Safety

Hazard Codes 
Xi,Xn
Risk Statements 
36/37/38-20/21/22
Safety Statements 
26-37/39-36/37/39-22-36
WGK Germany 
3
TSCA 
T
HazardClass 
IRRITANT
HS Code 
29339990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
132497
Product name
2,6-Dichloropyrazine
Purity
98%
Packaging
5g
Price
$50
Updated
2023/06/20
TCI Chemical
Product number
D1867
Product name
2,6-Dichloropyrazine
Purity
>99.0%(GC)
Packaging
5g
Price
$28
Updated
2025/07/31
TCI Chemical
Product number
D1867
Product name
2,6-Dichloropyrazine
Purity
>99.0%(GC)
Packaging
25g
Price
$81
Updated
2025/07/31
Sigma-Aldrich
Product number
132497
Product name
2,6-Dichloropyrazine
Purity
98%
Packaging
25g
Price
$80.25
Updated
2025/07/31
TRC
Product number
D435825
Product name
2,6-Dichloropyrazine
Packaging
100g
Price
$80
Updated
2021/12/16
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2,6-Dichloropyrazine Chemical Properties,Usage,Production

Chemical Properties

White Powder

Uses

2,6-Dichloropyrazine is used in the preparation of pyrazine and pyridine compounds as ATR kinase inhibitors. It is also used in the synthesis of oxacalixarenes containing nitrogen heterocycles.

Synthesis

The production method of 2,6-dichloropyrazine comprises the following steps: carrying out ammoniation and cyclization reactions of raw materials comprising methyl chloroacetate, glyoxal and the like to prepare 2-hydroxypyrazine sodium, reacting 2-hydroxypyrazine sodium with phosphorous oxychloride under the catalysis action of N,N-dimethylaminopyridine to prepare 2-chloropyrazine, and chlorinating 2-chloropyrazine by chlorine under the catalysis action of triethylamine with dimethyl formamide as a solvent to prepare 2,6-dichloropyrazine.

2,6-Dichloropyrazine Preparation Products And Raw materials

Raw materials

Glyoxal

Preparation Products

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2,6-Dichloropyrazine Suppliers

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View Lastest Price from 2,6-Dichloropyrazine manufacturers

Shandong Vital Biotechnology Co., Ltd.
Product
2,6-Dichloropyrazine 4774-14-5
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
100tons
Release date
2025-11-20
Wuhan JiyunZen Tech Co., Ltd.
Product
2,6-Dichloropyrazine 4774-14-5
Price
US $5.00-0.50/KG
Min. Order
1KG
Purity
99% hplc
Supply Ability
500TONS
Release date
2025-05-08
Hebei Chuanghai Biotechnology Co., Ltd
Product
2,6-Dichloropyrazine 4774-14-5
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100 mt
Release date
2024-11-07

4774-14-5, 2,6-DichloropyrazineRelated Search:

Glipizide Pyrazinamide Sulfachoropyrazine sodium 2,3-Dichloropyrazine,98%,2,3-DICHLOROPYRAZINE 2,5-DICHLOROPYRAZINE METHYL 3-AMINO-5,6-DICHLOROPYRAZINE-2-CARBOXYLATE,3-Amino-5,6-Dichloropyrazine-2-Carboxylic Acid Methyl Ester 2-AMINO-3,5-DICHLOROPYRAZINE 2-Dichloropyrazin 3,5-Dichloropyrazine-2-carboxylic acid Pyrazine 3,5-DICHLORO-2-ETHYLPYRAZINE METHYL 3,5-DICHLOROPYRAZINE-2-CARBOXYLATE 3,5-DICHLOROPYRAZINE-2-CARBOXAMIDE 2,6-DICHLORO-3-(TRIBUTYLSTANNYL)PYRAZINE 3,5,6-TRICHLORO-N-METHYLPYRAZIN-2-AMINE 3,5-Dichloropyrazine-2-carboxyamide 2,6-Dichloropyrazine 3,5-dichloropyrazine-2-carbaldehyde

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