1,2,3,4-TETRAHYDRO-ISOQUINOLIN-8-OL
- Product Name
- 1,2,3,4-TETRAHYDRO-ISOQUINOLIN-8-OL
- CAS No.
- 32999-37-4
- Chemical Name
- 1,2,3,4-TETRAHYDRO-ISOQUINOLIN-8-OL
- Synonyms
- H90102;1,2,3,4-Tetrahydro-8-isoquinolinol;1,2,3,4-TETRAHYDRO-ISOQUINOLIN-8-OL;8-Isoquinolinol, 1,2,3,4-tetrahydro-;8-Hydroxy-1,2,3,4-tetrahydroisoquinoline;1,2,3,4-Tetrahydroisoquinolin-8-ol - [T72322]
- CBNumber
- CB12459980
- Molecular Formula
- C9H11NO
- Formula Weight
- 149.19
- MOL File
- 32999-37-4.mol
1,2,3,4-TETRAHYDRO-ISOQUINOLIN-8-OL Property
- Boiling point:
- 294.3±40.0 °C(Predicted)
- Density
- 1.141±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- pka
- 9.21±0.20(Predicted)
- form
- solid
- color
- Off-white
Safety
- HS Code
- 2933499090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- P000216415
- Product name
- 1,2,3,4-Tetrahydroisoquinolin-8-ol
- Purity
- 95+%
- Packaging
- 250mg
- Price
- $185
- Updated
- 2021/12/16
- Product number
- OR938375
- Product name
- 1,2,3,4-Tetrahydroisoquinolin-8-ol
- Purity
- 95%
- Packaging
- 250mg
- Price
- $225
- Updated
- 2021/12/16
- Product number
- P000216415
- Product name
- 1,2,3,4-Tetrahydroisoquinolin-8-ol
- Purity
- 95+%
- Packaging
- 100mg
- Price
- $116
- Updated
- 2021/12/16
- Product number
- P000216415
- Product name
- 1,2,3,4-Tetrahydroisoquinolin-8-ol
- Purity
- 95+%
- Packaging
- 1g
- Price
- $463
- Updated
- 2021/12/16
- Product number
- CHM0379657
- Product name
- 1,2,3,4-TETRAHYDRO-ISOQUINOLIN-8-OL
- Purity
- 96.00%
- Packaging
- 5MG
- Price
- $499.25
- Updated
- 2021/12/16
1,2,3,4-TETRAHYDRO-ISOQUINOLIN-8-OL Chemical Properties,Usage,Production
Synthesis
3482-14-2
32999-37-4
Under the condition of ice-water bath, isoquinolin-8-ol (2.9 g, 20 mmol) was dissolved in acetic acid (15 mL) and sodium borohydride (3.78 g, 100 mmol) was added slowly. After the addition was completed, the reaction mixture was gradually warmed up to room temperature and the reaction was continued with stirring for 1 hour. Upon completion of the reaction, the reaction solution was slowly poured into ice (50 g) to quench the reaction, followed by extraction with ethyl acetate (100 mL × 2). The organic phases were combined, dried with anhydrous sodium sulfate, and concentrated under reduced pressure to remove the solvent. Finally, the target product 8-hydroxy-1,2,3,4-tetrahydroisoquinoline (2.12 g, 71% yield) was purified by silica gel column chromatography (eluent ratio of petroleum ether: ethyl acetate = 5:1).
References
[1] Patent: US2017/112833, 2017, A1. Location in patent: Paragraph 0455-0456
1,2,3,4-TETRAHYDRO-ISOQUINOLIN-8-OL Preparation Products And Raw materials
Raw materials
Preparation Products
1,2,3,4-TETRAHYDRO-ISOQUINOLIN-8-OL Suppliers
- Tel
- --
- Fax
- --
- contact@achemica.com
- Country
- Switzerland
- ProdList
- 6155
- Advantage
- 50
View Lastest Price from 1,2,3,4-TETRAHYDRO-ISOQUINOLIN-8-OL manufacturers
- Product
- 1,2,3,4-TETRAHYDRO-ISOQUINOLIN-8-OL 32999-37-4
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20T
- Release date
- 2024-08-14