Cyclohexanecarbonitrile, 4-hydroxy-
- Product Name
- Cyclohexanecarbonitrile, 4-hydroxy-
- CAS No.
- 24056-34-6
- Chemical Name
- Cyclohexanecarbonitrile, 4-hydroxy-
- Synonyms
- 4-hydroxycyclohexanecarbonitrile;4-hydroxycyclohexane-1-carbonitrile;Cyclohexanecarbonitrile, 4-hydroxy-
- CBNumber
- CB12473676
- Molecular Formula
- C7H11NO
- Formula Weight
- 125.17
- MOL File
- 24056-34-6.mol
Cyclohexanecarbonitrile, 4-hydroxy- Property
- Boiling point:
- 153-154 °C(Press: 12 Torr)
- Density
- 1.05±0.1 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 14.69±0.40(Predicted)
- Appearance
- Colorless to light yellow Oil
Safety
- HS Code
- 2926907090
N-Bromosuccinimide Price
- Product number
- H954983
- Product name
- 4-Hydroxycyclohexanecarbonitrile
- Packaging
- 100mg
- Price
- $110
- Updated
- 2021/12/16
- Product number
- CS-D1577
- Product name
- 4-Hydroxycyclohexanecarbonitrile
- Purity
- >97.0%
- Packaging
- 250mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- W4762
- Product name
- 4-Hydroxycyclohexanecarbonitrile
- Packaging
- 100mg
- Price
- $133
- Updated
- 2021/12/16
- Product number
- CS-D1577
- Product name
- 4-Hydroxycyclohexanecarbonitrile
- Purity
- >97.0%
- Packaging
- 1g
- Price
- $185
- Updated
- 2021/12/16
- Product number
- 074528
- Product name
- 4-Hydroxycyclohexanecarbonitrile
- Purity
- 95+%
- Packaging
- 500mg
- Price
- $255
- Updated
- 2021/12/16
Cyclohexanecarbonitrile, 4-hydroxy- Chemical Properties,Usage,Production
Synthesis
34916-10-4
24056-34-6
The general procedure for the synthesis of 4-hydroxycyclohexanecarbonitrile from 4-oxocyclohexanecarbonitrile was as follows: 4-oxocyclohexanecarbonitrile (10 g, 81.20 mmol, 1.00 eq.) and methanol (100 mL) were added to a 250 mL four-necked round-bottomed flask under inert nitrogen protection. Subsequently, sodium borohydride (1.52 g, 40.18 mmol, 0.50 eq.) was slowly added in an ice-water bath at 0 °C. The reaction mixture was stirred at room temperature for 1 hour. Upon completion of the reaction, the reaction was quenched by the addition of 20 mL of aqueous ammonium chloride. The reaction mixture was extracted with ethyl acetate (2 x 100 mL), the organic layers were combined and dried with anhydrous sodium sulfate. Finally, the organic layer was concentrated under reduced pressure to afford 4-hydroxycyclohexanecarbonitrile (10.02 g, 99% yield) as a colorless oil.
References
[1] Patent: US2017/166584, 2017, A1. Location in patent: Paragraph 0887-0889
[2] Annales de Chimie (Cachan, France), 1955, vol. <12> 10, p. 497,531
[3] Bulletin de la Societe Chimique de France, 1954, p. 610,612
[4] Patent: WO2009/156100, 2009, A1. Location in patent: Page/Page column 156
Cyclohexanecarbonitrile, 4-hydroxy- Preparation Products And Raw materials
Raw materials
Preparation Products
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