ChemicalBook > CAS DataBase List > Baicalin-7-diglucoside

Baicalin-7-diglucoside

Product Name
Baicalin-7-diglucoside
CAS No.
114482-86-9
Chemical Name
Baicalin-7-diglucoside
Synonyms
Oroxin B;Oroxin B【SMB00340】;Oroxin B >=98% (HPLC);Baicalin-7-diglucoside;Baicalein 7-diglucoside;Oroxin B, 10 mM in DMSO;Baicalein 7-O-diglucoside;Papilloside B/ xyloside B;Baicalein 7-diglucoside-RM;Baicalein-7-O-gentiobioside
CBNumber
CB12504484
Molecular Formula
C27H30O15
Formula Weight
594.52
MOL File
114482-86-9.mol
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Baicalin-7-diglucoside Property

Boiling point:
957.5±65.0 °C(Predicted)
Density 
1.76
storage temp. 
4°C, protect from light
solubility 
Soluble in methanol and water
form 
powder
pka
5.91±0.40(Predicted)
color 
Yellowish
InChIKey
HAYLVXFWJCKKDW-WEYZNFCFNA-N
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Safety

Safety Statements 
24/25
HS Code 
29389090
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
O691900
Product name
OroxinB
Packaging
5mg
Price
$330
Updated
2021/12/16
Usbiological
Product number
300732
Product name
Oroxin B
Packaging
20mg
Price
$490
Updated
2021/12/16
Biorbyt Ltd
Product number
orb105163
Product name
Oroxin B
Purity
>98%,Standard References Grade
Packaging
20mg
Price
$569.5
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
74095
Product name
OroxinB
Purity
98%
Packaging
20mg
Price
$733
Updated
2021/12/16
Biorbyt Ltd
Product number
orb594164
Product name
Oroxin B
Packaging
100mg
Price
$778.6
Updated
2021/12/16
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Baicalin-7-diglucoside Chemical Properties,Usage,Production

Chemical Properties

Soluble in methanol, ethanol, water, etc., insoluble in petroleum ether and chloroform. Derived from Oroxylum indicum, Bignoniaceae

Uses

Oroxin B is a component of the seed of O. (oroxylum) indicum and is used in traditional Chinese medicine for antiinflammatory, analgesic and other functions. It also has been observed to selectively induce tumor-suppressive ER stress and inhibits tumor-adaptive ER stress in B-lymphoma cells attenuating tumor growth.

in vivo

Oroxin B (30 mg/kg, i.p., 28 days) induces malignant lymphoma cell ER stress, and inhibits tumor growth in human lymphoma cell (Raji cell) xenograft model[2].
Oroxin B (160 μM of 10 μL, injected into the knee joints of mice) protects articular cartilage in destabilized medial meniscus (DMM) induced mice OA[3].
Oroxin B (200 mg/kg/day, oral gavage) relieves hepatic inflammation and inhibits MAFLD progression in HFD-fed rats[4].

Animal Model:Human lymphoma cell (Raji cell) xenograft model[2]
Dosage:30 mg/kg
Administration:i.p., 28 days
Result:Induced malignant lymphoma cell ER stress.
Inhibited tumor growth.
Prolonged overall survival of tumor-bearing mice.
Animal Model:HFD-fed rats[4]
Dosage:200 mg/kg/day
Administration:oral gavage
Result:Reduced the levels of plasma lipids, LPS, IL-6, and TNF-α.
Inhibited liver fibrosis by reducing collagen deposition.

Baicalin-7-diglucoside Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Baicalin-7-diglucoside manufacturers

Shanghai Standard Technology Co., Ltd.
Product
Oroxin B 114482-86-9
Price
US $0.00/mg
Min. Order
5mg
Purity
≥98%(HPLC)
Supply Ability
10 g
Release date
2019-12-26
Career Henan Chemical Co
Product
Baicalin-7-diglucoside 114482-86-9
Price
US $1.00/kg
Min. Order
1g
Purity
99%
Supply Ability
100KG
Release date
2018-12-24

114482-86-9, Baicalin-7-diglucosideRelated Search:


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