3-[[[2-Methoxy-4-(phenylamino)phenyl]amino]sulfonyl]-2-thiophenecarboxylicacidmethylester

ChemicalBook > CAS DataBase List > 3-[[[2-Methoxy-4-(phenylamino)phenyl]amino]sulfonyl]-2-thiophenecarboxylicacidmethylester

3-[[[2-Methoxy-4-(phenylamino)phenyl]amino]sulfonyl]-2-thiophenecarboxylicacidmethylester

Product Name: 3-[[[2-Methoxy-4-(phenylamino)phenyl]amino]sulfonyl]-2-thiophenecarboxylicacidmethylester
CAS No.: 1014691-61-2
Chemical Name: 3-[[[2-Methoxy-4-(phenylamino)phenyl]amino]sulfonyl]-2-thiophenecarboxylicacidmethylester
Synonyms: CS-738;GSK 0660;GSK-0660, >=98%;GSK-0660 (GSK0660);GSK0660 >=98% (HPLC);GSK-0660;GSK 0660;GSK0660;4-Chloro-3-iodo-2,3-dihydro-1H-pyrrolo[2,3-b]pyridine;METHYL 3-[(4-ANILINO-2-METHOXYPHENYL)SULFAMOYL]THIOPHENE-2-CARBOXYLATE;methyl 3-{[2-methoxy-4-(phenylamino)phenyl]sulfamoyl}thiophene-2-carboxylate;Methyl 3-(N-(2-Methoxy-4-(phenylaMino)phenyl)sulfaMoyl)thiophene-2-carboxylate
CBNumber: CB12518768
Molecular Formula: C19H18N2O5S2
Formula Weight: 418.49
MOL File: 1014691-61-2.mol

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3-[[[2-Methoxy-4-(phenylamino)phenyl]amino]sulfonyl]-2-thiophenecarboxylicacidmethylester Property

Boiling point:: 608.1±65.0 °C(Predicted)
Density: 1.413±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: DMSO: soluble10mg/mL, clear
form: powder
pka: 8.51±0.50(Predicted)
color: white to beige
InChIKey: NDFKBGWLUHKMFY-UHFFFAOYSA-N

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Safety

WGK Germany: 2

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: G5797
Product name: GSK0660
Purity: ≥98% (HPLC)
Packaging: 5mg
Price: $153
Updated: 2022/05/15

Cayman Chemical

Product number: 15272
Product name: GSK0660
Purity: ≥95%
Packaging: 5mg
Price: $97
Updated: 2024/03/01

Cayman Chemical

Product number: 15272
Product name: GSK0660
Purity: ≥95%
Packaging: 10mg
Price: $182
Updated: 2024/03/01

Cayman Chemical

Product number: 15272
Product name: GSK0660
Purity: ≥95%
Packaging: 25mg
Price: $427
Updated: 2024/03/01

Cayman Chemical

Product number: 15272
Product name: GSK0660
Purity: ≥95%
Packaging: 50mg
Price: $711
Updated: 2024/03/01

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3-[[[2-Methoxy-4-(phenylamino)phenyl]amino]sulfonyl]-2-thiophenecarboxylicacidmethylester Chemical Properties,Usage,Production

Uses

GSK0660 has been used to study the effects of bezafibrate (BZA) on hypertrophy.

Definition

ChEBI: 3-[(4-anilino-2-methoxyphenyl)sulfamoyl]-2-thiophenecarboxylic acid methyl ester is a sulfonamide.

General Description

GSK0660 has antiangiogenic property in oxygen-induced retinopathy. It also regulates tumor necrosis factor-α (TNFα)-induced inflammation in human retinal microvascular endothelial cells (HRMECs).

Biochem/physiol Actions

GSK0660 is a potent PPARβ/δ antagonist with a pIC50 of 6.8 (160 nM). GSK0660 is nearly inactive on PPARα and PPARγ with IC50s greater than 10 μM.

storage

Store at +4°C

3-[[[2-Methoxy-4-(phenylamino)phenyl]amino]sulfonyl]-2-thiophenecarboxylicacidmethylester Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 3-[[[2-Methoxy-4-(phenylamino)phenyl]amino]sulfonyl]-2-thiophenecarboxylicacidmethylester manufacturers

Career Henan Chemical Co

Product: methyl 3-[(4-anilino-2-methoxyphenyl)sulfamoyl]thiophene-2-carboxylate 1014691-61-2
Price: US $1.00/KG
Min. Order: 1KG
Purity: Min98% HPLC
Supply Ability: g/kg/ton
Release date: 2019-12-23

1014691-61-2, 3-[[[2-Methoxy-4-(phenylamino)phenyl]amino]sulfonyl]-2-thiophenecarboxylicacidmethylesterRelated Search:

Entospletinib (GS-9973) GS9620 GSK2643943A GS967 GSK J1 GSK-114 GSK-626616 Selonsertib Presatovir 4-HYDROXY-2-[(1E)-[4-(1-METHYLETHYL)PHENYL]METHYLENE]HYDRAZIDE

GSK-0660, >=98%

3-[[[2-Methoxy-4-(phenylamino)phenyl]amino]sulfonyl]-2-thiophenecarboxylicacidmethylester

GSK 0660

Methyl 3-(N-(2-Methoxy-4-(phenylaMino)phenyl)sulfaMoyl)thiophene-2-carboxylate

2-Thiophenecarboxylic acid, 3-[[[2-methoxy-4-(phenylamino)phenyl]amino]sulfonyl]-, methyl ester

4-Chloro-3-iodo-2,3-dihydro-1H-pyrrolo[2,3-b]pyridine

METHYL 3-[(4-ANILINO-2-METHOXYPHENYL)SULFAMOYL]THIOPHENE-2-CARBOXYLATE

3-(2-Methoxy-4-phenylamino-phenylsulfamoyl)-thiophene-2-carboxylic acid methyl ester

CS-738

GSK-0660 (GSK0660)

GSK-0660;GSK 0660;GSK0660

GSK0660 >=98% (HPLC)

methyl 3-{[2-methoxy-4-(phenylamino)phenyl]sulfamoyl}thiophene-2-carboxylate

1014691-61-2

Inhibitors