ChemicalBook > CAS DataBase List > 6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)chroman, 97%

6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)chroman, 97%

Product Name
6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)chroman, 97%
CAS No.
1002727-88-9
Chemical Name
6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)chroman, 97%
Synonyms
Chroman-6-boronic acid, pinacol ester;Chromane-6-boronic Acid Pinacol Ester;CHROMAN-6-YLBORONIC ACID PINACOL ESTER;Chroman-6-boronic acid, pinacol ester 99%;2-(ChroMan-6-yl)-4,4,5,5-tetraMethyl-1,3,2-dioxaborolane;6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)chroman, 97%;6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)chroman, 97%;2-(3,4-dihydro-2h-chromen-6-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane;2H-1-Benzopyran, 3,4-dihydro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-;3,4-Dihydro-2H-chromene-6-boronic acid, pinacol ester, 3,4-Dihydro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2H-chromene
CBNumber
CB12527946
Molecular Formula
C15H21BO3
Formula Weight
260.14
MOL File
1002727-88-9.mol
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6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)chroman, 97% Property

Boiling point:
373.5±31.0 °C(Predicted)
Density 
1.08±0.1 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
form 
powder
color 
Off-white
InChI
InChI=1S/C15H21BO3/c1-14(2)15(3,4)19-16(18-14)12-7-8-13-11(10-12)6-5-9-17-13/h7-8,10H,5-6,9H2,1-4H3
InChIKey
NDSHAELUPJMEBM-UHFFFAOYSA-N
SMILES
C1OC2=CC=C(B3OC(C)(C)C(C)(C)O3)C=C2CC1
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Safety

HS Code 
28402000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
C428890
Product name
2-(Chroman-6-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
Packaging
50mg
Price
$45
Updated
2021/12/16
Apolloscientific
Product number
OR16520
Product name
Chroman-6-boronic acid, pinacol ester
Purity
99%
Packaging
1g
Price
$82
Updated
2021/12/16
SynQuest Laboratories
Product number
6H60-1-17
Product name
Chroman-6-boronic acid, pinacol ester
Purity
99%
Packaging
1g
Price
$96
Updated
2021/12/16
Apolloscientific
Product number
OR16520
Product name
Chroman-6-boronic acid, pinacol ester
Purity
99%
Packaging
250mg
Price
$33
Updated
2021/12/16
SynQuest Laboratories
Product number
6H60-1-17
Product name
Chroman-6-boronic acid, pinacol ester
Purity
99%
Packaging
250mg
Price
$39
Updated
2021/12/16
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6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)chroman, 97% Chemical Properties,Usage,Production

Synthesis

67856-45-5

73183-34-3

1002727-88-9

Step 3: 6-Iodobenzodihydropyran (1.0 g, 3.85 mmol), pinacol ester of bisboronic acid (1.22 g, 4.81 mmol) and potassium acetate (1.10 g, 11.5 mmol) were dissolved in DMF (36 mL), and the solution was degassed by argon for 5 min. Subsequently, PdCl2(dppf)-DCM complex (314 mg, 0.38 mmol) was added and the reaction mixture was again degassed for 5 min. The reaction system was heated to 95 °C with continuous stirring for 5 hours. After completion of the reaction, it was cooled to room temperature. The crude reaction mixture was diluted with water and extracted three times with ethyl acetate (3 x 100 mL). The organic phases were combined and washed sequentially with water (100 mL) and brine (100 mL). The organic layer was dried over anhydrous magnesium sulfate, filtered and concentrated. The crude product was further purified by the CombiFlash system using gradient elution with ethyl acetate/hexane to afford the target product 3,4-dihydrochromene-6-boronic acid ester (840 mg, 84% yield).

References

[1] Patent: WO2009/62285, 2009, A1. Location in patent: Page/Page column 66-67
[2] Patent: WO2009/62308, 2009, A1. Location in patent: Page/Page column 76
[3] Patent: WO2009/62288, 2009, A1. Location in patent: Page/Page column 72-73

6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)chroman, 97% Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)chroman, 97% manufacturers

Zhuozhou Wenxi import and Export Co., Ltd
Product
6-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)chroMan 1002727-88-9
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-06-27
Career Henan Chemical Co
Product
6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)chroman, 97% 1002727-88-9
Price
US $1.00/kg
Min. Order
1kg
Purity
95%-99%
Supply Ability
100kg
Release date
2018-12-22

1002727-88-9, 6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)chroman, 97%Related Search:

Dibenzofuran 1-METHYL-4-[5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABORALAN-2-YL)PYRIDINE-2-YL]PIPERAZINE N-(4-(4,4,5,5-TetraMethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)acetaMide 2-CYANOPYRIDINE-4-BORONIC ACID PINACOL ESTER 6-FLUOROPYRIDINE-2-BORONIC ACID PINACOL ESTER 1-(5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PYRIDIN-2-YL)PIPERAZINE

  • 6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)chroman, 97%
  • 3,4-Dihydro-2H-chromene-6-boronic acid, pinacol ester, 3,4-Dihydro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2H-chromene
  • Chroman-6-boronic acid, pinacol ester
  • 2-(ChroMan-6-yl)-4,4,5,5-tetraMethyl-1,3,2-dioxaborolane
  • Chroman-6-boronic acid, pinacol ester 99%
  • 2-(3,4-dihydro-2h-chromen-6-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
  • CHROMAN-6-YLBORONIC ACID PINACOL ESTER
  • 2H-1-Benzopyran, 3,4-dihydro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-
  • Chromane-6-boronic Acid Pinacol Ester
  • 6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)chroman, 97%
  • 1002727-88-9
  • Organic boronic acid